RESUMO
Objective: To study the chemical constituents of Periploca Radix. Methods: The chemical constituents of Periploca forrestii were separated using various chromatographic techniques. Their structures were elucidated by spectral analysis. Results: Nineteen compounds were isolated from the 70% ethanol extract of P. forrestii, and identified as 3-O-caffeoylquinic acid methyl ester (1), 4-O-caffeoylquinic acid methyl ester (2), 5-O-caffeoylquinic acid methyl ester (3), 3-O-caffeoylquinic acid (4), 4-O-caffeoylquinic acid (5), 5-O-caffeoylquinic acid (6), 1, 3-di-O-caffeoylquinic acid (7), 3, 4-di-O-caffeoylquinic acid (8), 3, 5-di-O- caffeoylquinic acid (9), 4, 5-di-O-caffeoylquinic acid (10), protocatechuic aldehyde (11), p-hydroxybenzoic acid (12), o-hydroxybenzoic acid (13), syringic acid (14), vanillic acid (15), periforgenin A (16), Δ5-pregnene-3β, 17α, 20α-triol (17), periforgenin C (18), and periplogenin (19). Conclusion: Compounds 1-12 are isolated from the plants of genus Periploca Linn. for the first time, and compound 13 is isolated from P. forrestii for the first time.
RESUMO
Objective: To study the chemical constituents from the aerial part of Picris davurica and their anti-oxidative activity. Methods: Compounds were isolated by column chromatography of MCI, Sephadex LH-20, and ODS; Their structures and anti-oxidative activity were elucidated by NMR, MS, and DPPH methods. Results: On the basis of 1D-NMR, 2D-NMR, and ESI-MS data, eleven compounds were identified as caffeic acid (1), caftaric acid (2), chlorogenic acid (3), chicoric acid (4), 5-O-caffeoylshikimic acid (5), 3,4-di-O-caffeoylquinic acid (6), 3,5-di-O-caffeoylquinic acid (7), 4,5-di-O-caffeoylquinic acid (8) 4-O-caffeoylquinic acid (9), 5-O-caffeoylquinic acid (10), and 3,4-dihydroxy-6-(3,4-dihydroxy-E-styryl)-2-pyron-3-O-β-D-glucopyranoside (11). Conclusion: All the compounds reported in this study are isolated from the aerial part of P. hieracioides for the first time and show certain anti-oxidative activity.