RESUMO
Objective: To investigate afferent projections from the abducens nucleus to the contralateral medial rectus subnucleus of the oculomotor nucleus in rats.Methods:The means of retrograde hoseradish peroxidase tracing was used.Results:The internuclear neurons in the abducens nucleus were divided into two subgroups,the ventromedial and the ventrolateral ones. The axons of the internuclear nurons crossed the midline,ascended in the contralateral medial longitudinal fasciculus and intermediated exclusively in the contralateral medial rectus subgroups.Conclusion:The results imply that the internuclear meurons could play a major role in conjugate horizontal eye movement.
RESUMO
A Foville syndrome is rare. A 46-year-old man with a 3-year history of Behcet's disease presented with a right facial palsy and a limitation in the rightward movements of the eyes. On neurologic examination, there was no movement of eyes in the right hemifield during all kinds of eye movements, including saccade, smooth pursuit, vestibulo-ocular reflex, and optokinetic nystagmus. However, all the eye movements were normal in the left hemifiled except for slowed saccades toward the right. Additional features were right infranuclear facial paresis and extensor plantar response on left side. Brain MRI revealed high signal intensity lesions in the right pons both in the dorsal tegmentum and in the basis. Neurological signs resolved gradually with steroid treatment. Different clinical features between abducens nucleus syndrome and paramedian pontine reticular formation syndrome are briefly discussed. To the authors' knowledge, this is the first case report of a Foville syndrome caused by neuro-Behcet's disease.