Studies on chemical constituents in Guizhi Fuling Capsule (VI) / 中草药

Objective: To study the chemical constituents from the ethyl acetate and n-butanol extract of Guizhi Fuling Capsule. Methods: The chemical constituents were isolated and purified by multiple chromatographic methods. Their structures were identified on the basis of the spectral data and physicochemical properties. Results: Ten compounds were identified as 4-hydroxybenzoic acid (1), trans-O-methoxy cinnamic acid (2), trans-cinnamic acid (3), 4-hydroxycinnamic acid (4), 2,5-dihydroxy-4-methylacetophenone (5), ethyl gallate (6), vanillic acid (7), protocatechuic acid (8), affinoside (9), and benzyl-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (10). Conclusion: Compounds 1-10 are isolated from this plant for the first time.