A Case of Simultaneously Detecting Anti-D as an Autoimmune Antibody and Anti-E as an Alloimmune Antibody / 대한수혈학회지

We report here on a case of simultaneously detecting anti-D as an autoimmune antibody and anti-E as an alloimmune antibody without any evidence of autoimmune hemolytic anemia. A 66-year-old female with tuberculous spondylitis was admitted for removing a previously-placed surgical screw in her spine. She had received antituberculosis drugs and six units of AB, RhD positive packed red blood cells during the previous 6 months. The laboratory findings were as followings: the direct antiglobulin test was positive for IgG, the Rh phenotype of the erythrocytes was typed as group CcDe and RhD antigen was confirmed by the molecular method and the serological method to rule out partial-D.