Riesgo de desarrollar diabetes tipo 2 según LA FINDRISC y enfermedad arterial periférica / Risk of developing type 2 diabetes according to LA FINDRISC and peripheral arterial disease

La diabetes mellitus tipo 2 (DM2) representa un problema de salud pública, debido a su alta incidencia y prevalencia en el mundo. Un método para evaluar el riesgo de desarrollar DM2 es la escala Latin American Finnish Diabetes Risk Score (LA FINDRISC). La DM2 es un factor de riesgo de enfermedad arterial periférica (EAP) la cual puede ser diagnosticada mediante el índice tobillo-brazo (ITB). Objetivo: evaluar la presencia y severidad de enfermedad arterial periférica mediante ITB y relacionarlo con el riesgo de desarrollar DM2 según LA FINDRISC. Métodos: estudio descriptivo, correlacional, de corte transversal. Se evaluaron 134 personas y se les midió glicemia capilar para descartar diabetes. Posteriormente, se realizó el LA FINDRISC y el ITB. Resultados: El puntaje LA FINDRISC y la glicemia alteradas en ayunas aumentaron proporcionalmente (R2=0,5). Esta relación no se observó entre LA FINDRISC y el ITB arrojado por la población general. Sin embargo, al seleccionar los pacientes con vasos no comprimibles aparece una correlación positiva (R2=0,36) entre los dos instrumentos diagnósticos. Conclusión: LA FINDRISC y el ITB son instrumentos de diagnósticos no invasivo, sencillos y válidos para detectar riesgo de desarrollar DM2, y detectar presencia y severidad de enfermedad arterial periférica, respectivamente(AU)

Type 2 diabetes mellitus (DM2) represents a public health problem, due to its high incidence and prevalence in the world. One method to assess the risk of developing DM2 is the Latin American Finnish Diabetes Risk Score (LA FINDRISC) scale. DM2 is a risk factor for peripheral arterial disease (PAD) which can be diagnosed using the ankle-brachial index (ABI). Objective: to evaluate the presence and severity of peripheral arterial disease using ABI and to relate it to the risk of developing DM2 according to LA FINDRISC. Methods: descriptive, correlational, cross-sectional study. 134 people were evaluated, and capillary glycemia was measured to rule out diabetes. Subsequently, the LA FINDRISC and the ITB were held. Results: The LA FINDRISC score and impaired fasting blood glucose increased proportionally (R2 = 0.5). This relationship was not observed between LA FINDRISC and the ITB showed by the general population. However, when selecting patients with non-compressible vessels, a positive correlation (R2 = 0.36) appears between the two diagnostic instruments. Conclusion: FINDRISC and ITB are simple and valid non-invasive diagnostic instruments to detect the risk of developing DM2, and detect the presence and severity of peripheral arterial disease, respectively(AU)

The ankle-brachial index of type 2 diabetes / 国际中医中药杂志

Objective To study the ankle-brachial index of the diabetic gangrene. Methods ABI of the sixty cases with type 2 diabetes were measured. The results were divided into four groups: normal, gently abnormal moderate abnormal severely abnormal group. Results 30 cases were normal, occupying 50% (P＞0.05), gently and moderate abnormal attained 5 cases (8.33%) and 4 cases (6.67%) respectively, and the rests 21cases were severely abnormal, occupying 35% (P＞0.05).Conclusion The normal ABI was not always indicating type 2 diabetes without the gangrene or tendency.

Usefulness of Ankle Brachial Index to Predict the Extent of Coronary Stenosis / 中国康复理论与实践

@#ObjectiveTo examine the relationship between ankle brachial index (ABI) and the extent of coronary stenosis and evaluate the usefulness of ABI to predict the extent of coronary stenosis in old patients.Methods118 patients with coronary angiography were examined by ABI and hemostatic factors evaluation in addition to history collection.ResultsABI was inversely and significantly associated with Gensini score. ABI reduced significantly (P<0.001) in the patients with 3-vessel or left main coronary artery disease (CAD). But there were no significant differences in ABI among the patients with no CAD, 1-vessel or 2-vessel CAD. The corresponding area under the ROC curve was 0.75±0.045, with 95% CI=0.67～0.84 (P<0.001) in ABI in 3-vessel or left main CAD. When ABI≤0.9, it had a relatively high specificity (89.1%) and sensitivity (55.6%) for predicting the presence of 3-vessel disease or left main CAD.ConclusionIn the old patients, ABI is inversely and significantly associated with the extent of coronary stenosis, and ABI≤0.9 has a relatively high specificity and sensitivity for predicting the presence of 3-vessel or left main CAD.

Relation of Ankle Brachial Index (ABI) with the Other Traditional Risk Factors for Cardiovascular Disease / 中国慢性病预防与控制

Objective To assess the relationship of ankle brachial index (ABI) with the other traditional risk factors for cardiovascular disease (CVD). Methods A total of 2005 participants with a full data were selected from the survey of risk factors for CVD, carried out in Wuming, Guangxi province, 2004. The relationship of ABI with the other risk factors of CVD was analyzed by multivariate Logistic regression (backward stepwise; probability for stepwise, entry:0.05, removal:0.10). T test used in participants having risk factors vs the normal participants. The risk factors of CVD include age, sex, hypertension, high total cholesterol (HTC), high fasting plasma glucose (high FPG), low high-density lipoprotein cholesterol (low HDL-C), overweight or obesity, cigarette smoking, etc. Results The mean ABI values were significant in the groups having risk factors of overweight or obesity (P=0.02), low HDL-C (P= 0.04) and cigarette smoking (P

Relationship between High-Sensitivity C-Reactive Protein and Peripheral Vascular Disease in Maintenance Dialysis Patients / 대한신장학회잡지

BACKGROUND: Pheripheral vascular disease (PVD) is a risk marker for coronary artery disease, cerebrovascular disease, diabetes mellitus, hypertension and many other diseases. The cardiovascular mortality rate in dialysis patients is greater than that in general population. The aim of our study was to explore the distribution, risk factors of PVD by ankle- brachial index (ABI) and the relationship with inflammation by measurement of hsCRP in maintenance dialysis patients. METHODS: We measured ABI by doppler ultrasono in 130 maintenance dialysis patients (HD 86 patients, PD 44 patients) who undergoing dialysis for at least three months. Also, we classified the severity of PVD based upon ABI levels and compared the relation with systemic inflammation marker - hsCRP and many other clinical parameters. RESULTS: PD patients had significantly higher BMI with lower mean serum albumin for 6 months and serum BUN compared with HD patients. The frequency of PVD (ABI<0.9) was not different between the groups but ABI was significantly lower in HD patients than PD patients (0.95+/-0.21 vs 0.85+/-0.30, p<0.05). The mean of hsCRP tended to be lower in PD patients than in HD patients but did not reach stastical significance (0.31+/-0.35 vs 0.47+/-0.85, p=0.147). More severe PVD had higher mean hsCRP in whole dialysis patients and HD patients but PD patients didn't. The higher quartiles had older age, increased frequency and severity of PVD and significantly decreased ABI. The group with PVD(ABI<0.9) had a higher mean of hsCRP, older age, longer dialysis duration and diabetes. Multiple regression analysis demonstrated that hsCRP, diabetes, age, dialysis duration predicted ABI with R2=0.488 and p=0.000 in whole dialysis patients. hsCRP, age, dialyis duration, the presence of diabetes and coronary artery disease predicted ABI in HD patients. But only age predicted ABI in PD patients. CONCIUSION: We conclude that the risk factors of PVD may be different between the PD patients and HD patients. And the pathophysiologic implication on cardiovascular morbidity and mortality of same risk factors may be different between the groups.

Relationship between High-Sensitivity C-Reactive Protein and Peripheral Vascular Disease in Maintenance Dialysis Patients / 대한신장학회잡지

BACKGROUND: Pheripheral vascular disease (PVD) is a risk marker for coronary artery disease, cerebrovascular disease, diabetes mellitus, hypertension and many other diseases. The cardiovascular mortality rate in dialysis patients is greater than that in general population. The aim of our study was to explore the distribution, risk factors of PVD by ankle- brachial index (ABI) and the relationship with inflammation by measurement of hsCRP in maintenance dialysis patients. METHODS: We measured ABI by doppler ultrasono in 130 maintenance dialysis patients (HD 86 patients, PD 44 patients) who undergoing dialysis for at least three months. Also, we classified the severity of PVD based upon ABI levels and compared the relation with systemic inflammation marker - hsCRP and many other clinical parameters. RESULTS: PD patients had significantly higher BMI with lower mean serum albumin for 6 months and serum BUN compared with HD patients. The frequency of PVD (ABI<0.9) was not different between the groups but ABI was significantly lower in HD patients than PD patients (0.95+/-0.21 vs 0.85+/-0.30, p<0.05). The mean of hsCRP tended to be lower in PD patients than in HD patients but did not reach stastical significance (0.31+/-0.35 vs 0.47+/-0.85, p=0.147). More severe PVD had higher mean hsCRP in whole dialysis patients and HD patients but PD patients didn't. The higher quartiles had older age, increased frequency and severity of PVD and significantly decreased ABI. The group with PVD(ABI<0.9) had a higher mean of hsCRP, older age, longer dialysis duration and diabetes. Multiple regression analysis demonstrated that hsCRP, diabetes, age, dialysis duration predicted ABI with R2=0.488 and p=0.000 in whole dialysis patients. hsCRP, age, dialyis duration, the presence of diabetes and coronary artery disease predicted ABI in HD patients. But only age predicted ABI in PD patients. CONCIUSION: We conclude that the risk factors of PVD may be different between the PD patients and HD patients. And the pathophysiologic implication on cardiovascular morbidity and mortality of same risk factors may be different between the groups.

Relationship between ankle-brachial index and all cause mortality and cardiovascular disease mortality in female patients with atherosclerotic risk factors / 中国实用内科杂志

Objective To study the relationship between ankle-brachial index and all cause mortality and cardiovascular disease mortality in female Chinese patients with atherosclerotic risk factors.Methods A total of 1744 female patients with no less than two atherosclerotic risk factors were enrolled from several hospitals in Shanghai and Beijing.Baseline exams were measured.All the participants were followed up 13 months.Results The patients with PAD were significantly older than those without PAD[(72.42?9.158)years vs(65.89?10.366)years,P