Management of Cervical IVDP with Ayurvedic Interventions- A Case Report

Bones and joint disorders are common in the working age population and are conditions that affect passive (bones, joints) and/or active structures of the body (muscles, tendons, ligaments, peripheral nerves) . A 35 year old moderately built young gentle man working as an IT professional, complains of pain on nape of neck and back of the chest since one year. But however pain started radiating to left upper arm since past 4 months, night starts which apparently effecting sleep. Pain gets aggravated by physical activities like continuous sitting posture and gets relieved by analgesics and sleep at Chondroitin Sulphate. Cervical IVDP, can be considered as Apabahuka or Asthi majjagata vata . He was managed with external and internal medications like cervical traction, Lepanam, physio, Gandharvahasthadi kashayam, Sneha panam done with Gugguluthikthakam ghee, purgation done with Gandharvahasthadi erandam and Nasya done with Anutailam and Ksheerabala tailam

Reinventing nano drug delivery systems for hydrophilic active ingredients in Ayurvedic lipid based formulations containing poly herbal decoction

Background: Anu Tailam, an Ayurvedic medicated oil where ‘anu’ meant for atom and ‘tailam’ meant foroil and virtually meant for ‘oil of subtle or atomic size particles’. Since the major active ingredients in thisformulation are incorporated from the polyherbal decoction, it is expected to contain predominantlywater soluble ingredients.Objectives: It is hypothesized that these polar active botanical ingredients are present in the formulationshould be either suspended in the form of submicron particles or entrapped in the submicron vesicularstructures since the formulation did not show any precipitation or phase separation instead showed amonophasic oily liquid with very little moisture.Materials and Methods: In the present investigation, the micro architecture of the anu tailam is studiedvia column chromatography and high performance thin layer chromatography to prove the contents arepolar hydrophilic compounds followed by optical microscopy, photon correlation Spectroscopy (PCS) andenvironmental scanning electron microscope (ESEM) to study the particle/vesicle size of the formulation.Results: In this study, it was proved that the formulation contained only polar ingredients and can beextracted in polar solvents like methanol and ethanol. It was also found that the formulation taken forstudy contained nano particles of the active botanical ingredients embedded in a network of vesicularstructures of the lipid base.Conclusion: The selected Ayurvedic formulation ‘anutailam’ found to contain novel nano drug deliverysystem to deliver water soluble ingredients across barriers.