Atypical Cheiro-oral Syndrome Presented With Bilateral Perioral Sensory Symptoms in Unilateral Thalamic Infarction

Cheiro-oral syndrome is a unilateral sensory impairment that is restricted to the homolateral hand and perioral area. An unusual clinical presentation with bilateral perioral involvement has also been described. Most of the responsible lesions involved the paramedian pontine tegmentum; thalamic involvement is extremely rare. We report herein a patient who presented with purely sensory symptoms involving the bilateral perioral regions and the distal thumb and index finger of the left hand following a small infarction in the right lateral thalamus.