RESUMO
Objective To study the real world of bicyclol tablets in the treatment of viral hepatitis and its influence on platelets.Methods The hospital information system (HIS) was selected from 18 Triple-A hospitals in China on patients with bicyclol tablets information as exposed group (2 690 cases),patients with unused bicyclol tablet (2 690 cases) as an exposed group,an exception occurs of platelet as an index of the ending.Results The incidence of abnormal platelet difference in two groups before the treatment were not statistically significant.The incidence of abnormal platelet reduce between two groups have statistical significance,can be thought of exposure of abnormal lower rate (11.75%)lower than that of non exposed group(15.17%) (P<0.01).Conclusion Bicyclol piece have signficantly curative effect on the treatment of viral hepatitis.It shows more safety,and less impact on platelets.It is worth to be used in clinical practice.
RESUMO
Objective To observe the effect of bicyclol tablets in preventing liver damage caused by anti -tu-berculosis drugs .Methods According to the different treatment method ,100 tuberculosis patients were divided into the treatment group and the control group ,each group 50 cases.Both groups were given standardized anti-TB treat-ment,while the treatment group were added to bicyclol tablets throughout the treatment ,and add the control group were added to silibinin capsule throughout the treatment .The liver damage of the two groups were compared .Results There were 6 cases who had liver damage in treatment group (6.0%),and 20 cases who had liver damage in the con-trol group(20.0%),and there was significant difference between the two groups (χ2 =8.66,P<0.01).Conclusion Bicyclol tablets is more effective in preventing liver damage caused by anti-tuberculosis drugs than silibinin cap-sules.