A new aurone glycoside from Bidens parviflora / 中草药

Objective: To study the chemical constituents of Bidens parviflora. Methods: The ethyl acetate fraction of 80% ethanol extract from B. parviflora was isolated and purified by silica, polyamide, Sephadex LH-20, and HPLC, then the structures of obtained compounds were identified by physicochemical properties and spectral data. Results: Ten compounds were isolated and identified as Z-6-O-(4″-O-acetyl-6″-O-p-coumaroyl-β-D-glucopyranosyl)-6,7,3’,4’-tetrahydroxyaurone (1), okanin-4’-O-β-D-(6″-O- acetyl)-glucoside (2), Z-6-O-(4″,6″-diacetyl-β-D-)-7,3’,4’-tetrahydroxy aurone (3), 6,7,3’,4’-tetrahydroxy aurone (4), isookanin (5), syringic acid-4-O-α-L-rhamnopyranoside (6), okanin-4’-O-β-D-(6″-trans-p-coumaroyl)-glucoside (7), okanin-4’-O-β-D-(4″-acetyl- 6″-trans-p-coumaroyl)-glucoside (8), quercetin-3,4’-dimethyl ether-7-O-rutinoside (9), and cordifolioidyne B (10). Conclusion: Compound 1 is a new compound named as bidenoside I, compounds 6 and 10 are isolated from the genus Bidens for the first time, other compounds are isolated from this plant for the first time.

Caffeoylquinic acid derivatives from Bidens parviflora and their antihistamine release activites / 中草药

Objective Based on the activities of antihistamine release to study the compounds from Bidens parvi-flora and find biological active compounds. Methods The chemical constituents from B.parviflora were isolated by silica gel and Sphadex LH-20 column chromatographies and purified by preparative HPLC. The chemical structures had been identified by physiochemical properties and spectroscopic methods. Results Six caffeoylquinic acid derivatives were identified as 3, 5-di-O-caffeoylquinic acid ( Ⅰ ),3, 4-di-O-caffeoylquinic acid ( Ⅱ ), 4, 5-di-O-caffeoylquinic acid ( Ⅲ ), 4-O-caffeoylquinic acid ( Ⅳ ), 5-O-caffeoylquinic acid ( Ⅴ ), 4-[3-(3, 4-dihydroxy-phenyl)-acryloyloxy]-2, 3-dihydroxy-2-methyl-butyric acid ( Ⅵ ). Conclusion Compounds Ⅰ - Ⅵ are first obtained from B. parviflora and Ⅵ is new one. Some of the compounds exhibit the activities in antiallergic assays. Moreover, the structure-activity relationships of these compounds have been also discussed in this paper.

Phenolic glucosides from Bidens parviflora and their anti-histamine activities / 中草药

100 ?g/mL, respectively. Conclusion Compounds Ⅰ-Ⅴ are isolated from B. parviflora for the first time, Ⅲ is a new phenolic glucoside named as bidenphenol glucoside. Compounds Ⅰ-Ⅴ exhibit the activities of anti-histamine release from rat mast cell stimulated by antigen-antibody reaction.