1.
Journal of Jilin University(Medicine Edition)
;
(6): 568-570, 2000.
Artigo
em Chinês
| WPRIM
| ID: wpr-412250
RESUMO
Objective:To investigate the effect of the BmK-9-(2) on the sodium current in guinea-pigventricular myocytes. Methods:The whole cell patch-clamp technique was used. Results:The BmK-9-(2)increased the magnitude of the peak inward sodium current (27 %) ,peak sodium conductace (17 %) and theprolong time course of sodium channel inactivation (8%) and there was no effects on calcium channels.Conclusion:BmK-9-(2) can activate sodium channel and prolong the inactivated course of myocytes.