1.
Journal of International Oncology
;
(12): 806-809, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-671345
RESUMO
Stem cells are characterized by the ability to renew themselves and differentiate into a di-verse range of specialized cell types.Bmi1 gene has been determined to play critical roles in the self-renewal of stem cells.Many of the tumor originated in stem cells.Enhanced self-renewal capability in stem/progenitor cells changes its biological characteristic and drives tumor initiation