Application of fMRI Technology in Exploration of Central Brain Localization among Premenstrual Syndrome Patients with Liver-qi Depression in Resting-state / 世界科学技术-中医药现代化

This study was aimed to explore brain regions which were closely related to the disease onset of premenstrual syndrome (PMS) with liver-qi depression. The BOLD-functional magnetic resonance imaging (fMRI) was used in the study. The processing of imaging data was based on the SPM 8 software and the REST software of the matlab platform. Each cluster was more than 389 continuous voxel. The brain region with single voxel of P < 0.05 (corrected) was defined as region with statistical significance. The 2 Sample T-Test was applied in the case group and the control group. The results showed that compared with the normal control group, the frontal lobe, occipital lobe, insula, limbic lobe, basal nuclei, and cingulate gyrus were activated in the PMS with liver-qi depression cases. It was concluded that the disease onset of PMS with liver-qi depression cases was related to brain regions such as frontal lobe, occipital lobe, insula, limbic lobe, basal nuclei, and cingulate gyrus.

John Hughlings Jackson: um neurologista inglês / John Hughlings Jackson: a British neurologist

John Hughlings Jackson tornou-se médico e neurologista por uma via atípica e sem frequentar qualquer universidade. Entretanto, sua mente brilhante e a admirável capacidade de trabalho levaram-no a produzir conhecimentos que repercutem até os dias de hoje, nas áreas do diagnóstico neurológico, epilepsia, localização cerebral, níveis evolucionários do sistema nervoso e sua hierarquia, entre outros. Diversas das condições que descreveu foram designadas com seu nome. É admirável que essa produção médico-científica tenha sido baseada inteiramente na sua aguçada capacidade de observação clínica. Foi a personalidade que mudou a neurologia inglesa, dando-lhe um status que carecia no meio nacional e internacional. É considerado o "pai" da neurologia inglesa.

John Hughlings Jackson became a physician and neurologist through an atypical way, and without attending any university. However, his brilliant mind and amazing capacity for work led him to produce knowledge that resounds until the present days, in areas of neurological diagnosis, epilepsy, brain localization, evolutionary levels of the nervous system and their hierarchies, among others. Several conditions that he described were named after him. It is admirable that this medical-scientyphic production was founded entirely in his sharp ability of clinical observation. He was the personality that changedthe English neurology providing a status it lacked in the national and international milieu. He is considered the "father" of the English neurology.