Caracterización del asma grave no controlada en adultos mayores de 60 años / Characterization of Severe Uncontrolled Asthma in Adults Older Than 60 Years

Introducción: Los pacientes mayores de 60 años suelen tener un asma más grave, menos controlada y peor función pulmonar que los jóvenes. Objetivo: Caracterizar a los pacientes mayores de 60 años con asma grave no controlada. Métodos: Se realizó un estudio observacional descriptivo, prospectivo y transversal en el Hospital Neumológico Benéfico Jurídico en el período comprendido entre enero del 2020 y enero del 2021. Resultados: Edad predominante 60-69 años (76,5 por ciento). Mujeres (61,8 por ciento). Antecedentes familiares de asma o alergia (64,7 por ciento). Asma de larga evolución (85,3 por ciento). Asma asociada a obesidad y mal control (55,9 por ciento). Reversibilidad del VEF1 (volumen espiratorio forzado en el primer segundo) después de la aplicación del broncodilatador (26,5 por ciento). Adherencia al tratamiento (61,8 por ciento). El riesgo futuro de resultados adversos fue bajo en el 58,8 por ciento, es el principal factor, el mal control actual en el 100 por ciento. Conclusiones: El asma grave no controlada en mayores de 60 años es más frecuente en el sexo femenino, los pacientes suelen tener antecedentes familiares de asma o alergia, presentar asma de larga evolución, obesidad asociada al mal control, disminución de la reversibilidad del VEF1 con la aplicación del broncodilatador, mala adherencia al tratamiento y el mal control actual como riesgo futuro de la enfermedad(AU)

Introduction: Patients older than 60 years tend to have more severe, less controlled asthma and worse lung function than younger people. Objective: To characterize patients older than 60 years with severe uncontrolled asthma. Methods: A descriptive, prospective and cross-sectional observational study was carried out at Benéfico Jurídico Pneumological Hospital from January 2020 to January 2021. Results: The age group 60-69 years (76.5percent) predominated. Women also predominated (61.8percent), as well as family history of asthma or allergy (64.7percent), and long-standing asthma (85.3percent). Asthma associated with obesity and poor control was 55.9percent. The reversibility of the forced expiratory volume in the first second (FEV1) after the application of the bronchodilator was 26.5percent. The adherence to treatment was 61.8percent. The future risk of adverse results was low (58.8percent), which is the main factor, the current poor control in 100percent. Conclusions: Severe uncontrolled asthma in people over 60 years of age is more frequent in women, patients usually have family history of asthma or allergy, there is long-term asthma. It was observed that obesity is associated with poor control, the decreased FEV1 reversibility with the application of the bronchodilator, poor adherence to treatment and poor current control as a future risk of the disease(AU)

A Prospective Study on Predictive Value of Absolute Eosinophil Count for Bronchodilator Reversibility in COPD Patients

INTRODUCTION: Chronic obstructive pulmonary disease (COPD) patients are prone to exacerbation that account for significant morbidity and mortality. According to physio-pathologic and clinical-functional viewpoints, bronchiectasis and COPD have some common characteristics, it has been observed that bronchiectasis was present in up to 50% of patients with moderate to severe COPD . This observation suggests that COPD is a risk factor for bronchiectasis. METHODOLOGY: This study was included 120 totals who were attending the OPD in the department of TB Chest. This study was conducted in the Department of TB & Respiratory Diseases, Shri Dev Suman Subharti Medical College, Dehradun. RESULT: In our study we were included 120 total number of cases, out of all cases 35.5% cases were found from eosinophilic COPD group & 62.5% were found non-eosinophilic COPD group. In eosinophilic COPD group,42 male and 3 females were found. While in non-eosinophilic COPD group ,60 male and 15 females were found. CONCLUSION: This study suggested that flow reversibility associated with this volume reversibility was more in eosinophilic COPD.

The Complementary Role of FEV6 in Bronchodilator Reversibility Test for the Old Age / 결핵및호흡기질환

BACKGROUND: In the measurement of bronchodilator reversibility, the forced expiratory volume in one second(FEV(1)) and the forced vital capacity(FVC) are commonly used parameters and recommended criteria for the reversibility requiring an increase of more than 200ml and 12% above the baseline, respectively. However, aged patients do not often meet the criteria of an increase in volume(>200ml) even though the medical history of that patient is adequate for asthma. This study investigated the role of the forced expiratory volume in six seconds(FEV(6)) in the bronchodilator reversibility test in elderly patients. METHODS: A total of 236 patients more than 65 years of age with a FEV(1)/FVC ratio or = 80% of the predicted value, Group II: 60%

Clinical analysis of COPD with bronchodilator reversibility in 47 patients / 中国实用内科杂志

Objective To analyze the clinical features of chronic obstructive pulmanory disease(COPD)with different results of bronchodilator reversibility test.Methods A total of 47 cases of COPD were selected and given bronchodilator reversibility test and lung fuction who were divided into two groups according to the bronchodilator reversibility test.We compared these two groups with sex,age,smoke history,body mass index,levels of IgE,eosinophil and lung function.Results The positive group had a shorter history of smoking and a higher level of IgE.The amelioration of FVC,FEV1,FRC,MEF 75% and MEF 50% was higher in the positive group than the negative(P