Effect of lead acetate on growth of murine mesenchymal stem cells / 吉林大学学报(医学版)

Objective To explore the effect of lead acetate on the growth of murine mesenchymal stem cells in vitro.Methods 40.00,60.00 and 100.00 ?mol?L-1 of lead acetate were used in the culture of colony-forming unit-fibroblast(CFU-F),the effect on the rate of colony-forming and the rule of variation were observed.Results The rates of colony-forming were(3.30?0.20),(2.40?0.10) and(1.57?0.21)/105,when the doses of lead acetate were 40.00,60.00 and 100.00 ?mol?L-1 and there were significant differences compared with control group(4.20?0.20)/105,P