Research and reflection on standard decoction of Chinese materia medica / 中草药

The characteristics of Chinese materia medica (CMM) decoction with its composition, usage, and dosage can be flexibly changed with the actual situation. It has been used for thousands of years and it is still the most commonly used form of Chinese medicine. However, there are few research on the quality of “decoction” of CMM. Some scholars put forward the concept of “standard decoction”. As a standard substance and standard system, the standard decoction of CMM not only ensures the efficacy of clinical medication, but also can be used to standardize other dosage forms of clinical medicine. In this article, the influencing factors of the “standard” decoction were analyzed and discussed to standardize the preparation of decoction process and ensure the accuracy of the clinical medication and the consistency of efficacy, and provide reference for the research of formula granules, classical prescription, and CMM compound.

Research ideas and progress on screening and identification of pharmacodynamic substance of Chinese materia medica / 中草药

Study on the pharmacodynamic material basis of Chinese materia medica (CMM) is the key and difficult points of CMM research due to its complicated components and synergistic effect of multiple pathways and multiple targets in pharmacological action. Currently, research ideas and research methods of the pharmacodynamic material basis of CMM are being constantly innovated. In this review, research ideas and progress on screening and identification of pharmacodynamic substance of CMM were summarized. It suggested that the research model of interdisciplinarity, multi-dimensional screening and evaluation should be established, in order to provide references for further and comprehensively revealing the mechanism of action of CMM and the law of compatibility, and establishing quality evaluation system of CMM.