Validity of the New Caries Activity Test using Real-Time Polymerase Chain Reaction / 대한소아치과학회지

Periogen is a new caries activity test using real-time polymerase chain reaction. The aim of this study was to assess the validity of Periogen by evaluating the correlation with dmft, dmfts indices and comparing with Cariview and caries risk assessment tool (CAT).83 children under 6 participated in this study. Dmft, dmfts indices and CAT were collected through an examination of oral health status. Plaque samples for Periogen and Cariview were collected and manipulated according to the manufactures' instructions.The correlation coefficient of Periogen, Cariview and CAT with the dmfts index were 0.38, 0.56 and 0.66 in each (p < 0.01). The sensitivity of Periogen, Cariview and CAT were 43%, 76% and 95% and specificity were 80%, 72% and 74% respectively. Area under curve under the receiver operating characteristic curves in each method indicated 0.69, 0.81 and 0.85.CAT and Cariview were more effective in evaluation the risk of dental caries than Periogen so far. To be used Periogen clinically, more improvements for higher validity were needed.

Correlation of Caries Experience and Activity between Mothers and Their Children Using a Colorimetric Test / 대한소아치과학회지

The purpose of this study was to compare the validity of Cariview®, a new colorimetric caries activity test, with CRT® bacteria, a conventional bacterial culture method. In addition, this study assesses the correlation between the dental caries experience and activity between mothers and their children.34 pairs of mothers and their children under the age of 6 years participated in this study with informed consent. After filling out a questionnaire and oral examination, the two caries activity tests above were performed on each subject.In the results, Cariview® scores were statistically significant with children's caries experience (r = 0.598, p <0.01) and showed higher correlation than CRT® bacteria scores. Cariview® scores showed statistically significant correlation with the number of decayed teeth in both mothers and children (p <0.05). In both Cariview® and CRT® bacteria tests, there was no statistically significant correlation between caries experience and caries activity (p > 0.05).Cariview® colorimetric test will be clinically useful for predicting future caries risk and establishing a preventative strategy in pediatric dentistry.

Assessing the clinical validity of a new caries activity test using dental plaque acidogenicity / 대한구강보건학회지

OBJECTIVES: This study was aimed at evaluating the clinical usability of a new caries activity test (Cariview(R)), which was based on the acidogenic potential of plaque by evaluating it's correlation with the DMFT index and comparing the results of Cariview(R) with those of previous caries activity tests in an adult group. METHODS: Teeth of 74 subjects were examined, and the DMFT index was calculated according to World Health Organization (WHO) criteria to determine the past caries experience. Caries activity tests were performed according to manufacturer's instructions. For Cariview(R) test, plaque samples were collected from the tooth surface by using a sterile cotton swab and incubated at 37degrees C for 48 h; an indicator was added to observe the color changes according to the plaque acidogenicity. The subjects were classified into three groups (Low, Moderate, High) according to the level of caries risk. The data were assessed using one-way ANOVA to compare the caries experiences of risk groups according to the caries activity test results, and the relationships between the caries activity tests and the DMFT index were evaluated. RESULTS: The overall mean DMFT index was 5.70+/-4.42. There was a significant difference in the DMFT index among the caries risk groups (Low, Moderate, High) according to the Cariview(R) test result (P=0.036). Further, there was a positive correlation between the Cariview(R) score and the DMFT index (r=0.23, P=0.047) and between the Cariview(R) score and the previous caries activity tests score (P<0.01). CONCLUSIONS: The new caries activity test (Cariview(R)) can be easily used at dental clinics and enables precise caries risk assessment.