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1.
Artigo | IMSEAR | ID: sea-184008

RESUMO

Chemical leukoderma is a hypomelanotic disorder due to destruction of melanocytes or inhibition of melanogenesis secondary to application of harmful chemicals household or industrial. It can be easily diagnosed clinically by a positive history of frequent exposure to a depigmenting agent at the site corresponding with the pattern of the object applied. It has a psychosocial significance because of the dyspigmented presentation of the disease which often simulates other conditions associated with social stigma, like leprosy or vitiligo. Here, we report a case of thirty year old female with chemical leukoderma who presented to us with depigmented patches over forehead (bindi leukoderma) and dorsae of feet (footwear dermatitis) caused by application of sticker bindi and wearing of rubber footwear respectively. Complete repigmentation was observed after treatment with topical corticosteroids and melanocyte transfer surgery.

2.
Korean Journal of Dermatology ; : 832-833, 2016.
Artigo em Coreano | WPRIM | ID: wpr-98570

RESUMO

No abstract available.

3.
Annals of Dermatology ; : 241-244, 2010.
Artigo em Inglês | WPRIM | ID: wpr-54687

RESUMO

Chemical leukoderma occurs due to the toxic effect of a specific chemical preceding allergic contact dermatitis. The mechanism is either destruction or inhibition of melanocytes by the offending substance. Clinicohistopathologically, no absolute criteria can differentiate chemical leukoderma from vitiligo. However, chemical leukoderma can be diagnosed clinically by a history of repeated exposure to a known or suspected depigmenting agent at the primary site. There is no agreed treatment guideline for chemical leukoderma. We report a healthy 51-year-old man who had multiple hypopigmented macules and patches on his face, neck, arms and legs after exposure to occupationally related chemicals. The lesions were recalcitrant to topical corticosteroids, but they showed much improvement after 3 cycles of systemic steroid pulse therapy. We suggest this therapy may be a good treatment option for chemical leukoderma.


Assuntos
Humanos , Pessoa de Meia-Idade , Corticosteroides , Braço , Dermatite Alérgica de Contato , Perna (Membro) , Melanócitos , Pescoço , Ocupações , Vitiligo
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