Study on phenylpropanoids and lignans from Selaginella involven / 中草药

Objective: To study the chemical constituents of phenylpropanoids and lignans in Selaginella involven and to explore their roles in the plants evolution of Selaginella P. Beauv. Methods: The chemical constituents were isolated and purified by polyamide, macroporous resin, and Sephadex LH-20 column chromatography, and their structures were elucidated by chemical and spectroscopic methods. Results: Fifteen compounds were identified as 3-(3-hydroxyphenyl)-propionic acid (1), 3-(3-hydroxyphenyl)-methyl propionate (2), cinnamic acid (3), 3-hydroxy-1-(3-methoxy-4-hydroxyphenyl) propan-1-one (4), 3-hydroxy-1-(3,5-dimethoxy-4-hydroxyphenyl) propan-1-one (5), (+)-wikstromol (6), (-)-nortrachelogenin (7), (+)-matrairesinol (8), (5H)-2-furanone-3,4-bis[(4-hydroxy-3-methoxyphenyl) methyl] (9), acutissimalignan B (10), detetrahydroconidendrin (11), syringaresinol (12), 3,3',5-trimethoxy-4',7-epoxy-8,5'-neolignan-7-ene-4,9,9'-triol-9-aldehyde (13), ciwujiatone (14), and tarennone (15), respectively. Conclusion: Compounds 1-15 are isolated from this plant for the first time. Among them 1-3, 9-11, and 13-15 are isolated from the plants of Selaginella P. Beauv. for the first time. The discovery of a series of mustards, coniferyl alcohols, and their derivatives, which is the representative of phenypropanoids and lignans from S. involven, plays an important role in the development of plants in Selaginella P. Beauv..

Chemical constituents from Acanthopanax senticosus / 中草药

Objective: To study the chemical constituents of Acanthopanax senticosus. Methods: The compounds were separated and purified by column chromatography and their structures were identified by spectroscopic methods. Results: Twelve compounds were isolated from the chloroform and n-butanol extract of A. senticosus, and their structures were determined as ciwujiatone (1), eleutheroside B1 (2), tachioside (3), alimoxide (4), erythro-1-(4-hydroxy-3-methoxy-phenyl)-2-{4-[(E)-3-hydroxy-1-propenyl] -2-methoxy-phenoxy}-1,3-propanediol (5), erythro-1,2-bis(4-hydroxy-3- methoxyphenyl)-1,3-propanediol (6), tortoside A (7), episyringaresinol 4′-O-β-D-glucopyranoside (8), (+)-lyoniresinol (9), benzyl-O-α-L-rhamno-pyranosyl (1→6)-β-D-glucopyranoside (10), 2,6-dimethoxy-4-(3-hydroxy-propen-1-yl) phenyl-4-O-α-L-rhamno-pyranosyl- (1→6)-β-D-glucopyranoside (11), and nicotinamide (12). Conclusion: Compounds 3-5 and 10-12 are isolated from A. senticosus for the first time.