Causes of false-positive anti-HCV in non-syndromic cleft lip and palate with serum chemiluminescence test / 中国免疫学杂志

Objective:To investigate the causes of false-positive anti-HCV in non-syndromic cleft lip and palate with serum chemiluminescence test. Methods:We performed a hospital-based,case-control study of 4 050 patients with non-syndromic cleft lip and palate and 8 547 control patients without cleft lip and palate to evaluate associations between positive anti-HCV and non-syndromic cleft lip and palate. CLIA test were used for detect anti-HCV in control group. RIBA and FQ-PCR were used for confirming the result of the positive samples of CLIA test. CLIA test were used for detect anti-HCV in case group until CLIA test was negative. IgG,RF and ANA were used for case-control comparisons. Results:The detection rate of anti-HCV were higher in the case group than that of control group (P<0. 05). The false-positive rate was 1 percent based on testing of 4 050 patients. These samples were negative after opration 1-19 months. There were no change among IgG, RF and ANA in the false-positivepatients. Conclusion: False-positive anti-HCV in non-syndromic cleft lip was possible associated with abnormal plasma metabolic product. It can be excluded by track monitoring.

Estado nutricional de niños afectados por fisuras labiopalatinas / Nutritional status of children suffering cleft lip and palate

Objetivo: determinar la prevalencia de malnutrición en niños afectados por fisuras del labio asociadas a paladar hendido. Métodos: estudio descriptivo de tipo transversal. La muestra consistió en 86 pacientes de edad comprendida entre 1 y 15 años, que fueron atendidos en el Hospital Pediátrico Hermanos Cordové de Manzanillo, Cuba, entre 1995 y 2010. Resultados: predominó la desnutrición moderada, y los mayores índices se observaron en el grupo de menor edad. Conclusiones: la prevalencia de desnutrición en este grupo resultó menor que la encontrada en otras muestras tomadas de poblaciones normales

Objective: to determine the prevalence of malnutrition in children suffering cleft palate-associated cleft lip. Methods: a cross-sectional descriptive study. The sample was made up of eighty six 1-15 years-old patients who had been seen at Hermanos Cordove pediatric hospital located in Manzanillo, Cuba from 1995 to 2010. Results: moderate malnutrition status prevailed and the highest indexes were observed in the smallest age group. Conclusions: malnutrition prevalence in this group was lower than that found in other samples from normal child populations