Study on Regularity of Professor Shen Zhongyuan's Treatment of Hepatitis B Liver Cirrhosis Based on Data Mining / 世界科学技术-中医药现代化

Through the clinical research information sharing system,this study was aimed to explore the law of Professor Shen Zhongyuan's treatment of hepatitis B liver cirrhosis,and to inherit academic thoughts of senior famous traditional Chinese medicine (TCM) doctors.The structured electronic medical record system was used.The information of Professor Shen Zhongyuan expert outpatient with hepatitis B cirrhosis was collected from September 2012 to September 2015.And then,the medical data were extracted and analyzed to find out the medication regularity of hepatitis B cirrhosis and the distribution rule of the taste tropism of herbal medicine in the treatment.The results showed that 388 cases of hepatitis B cirrhosis patients with a total of 127 kinds of herbal medicine.The cumulative using frequency of herbal medicine was 5595.The most commonly used 10 types of Chinese medicine were turmeric,citrus aurantium,cuttlefish bone,atractylodes,rhizoma coptidis,salvia miltiorrhiza,lobelia,artemisia capillaris,fructus trichosanthis,and chicken's gizzard-membrane.The taste of mostly used Chinese medicine is bitter and sweet,followed by acrid.The nature of Chinese medicine is cold,slightly cold,warm and even.The meridian tropism of Chinese medicine is mainly to the liver and spleen meridian.It was concluded that Professor Shen in treatment of hepatitis B cirrhosis drug laws was often to use heat-clearing and toxin-relieving,qi-reinforcing and spleen-invigorating medicine,liver-soothing and qi-regulating medicine,blood-activating and stasis-removing medicine.The nature of herbal medicine used is mostly cold,slightly cold,warm and even.It is based on the TCM syndrome differentiation and treatment thought of “regulating yin-yang to maintain the balance.” It showed the important principle of “toxin-removing,stasis-removing,liver-regulating and spleen-strengthening” by professor Shen.

Correlation Analysis of Syndromes and Symptoms of TCM AECOPD Based on Clinical Research Information Sharing System / 世界科学技术-中医药现代化

This study was aimed to analyze correlation between traditional Chinese medicine (TCM) syndromes and symptoms of acute exacerbation chronic obstructive pulmonary disease (AECOPD) based on complex network in order to provide a scientific basis for TCM syndrome amendments of diagnostic criteria, and explore relevant technologies to promote its application. By way of the current Clinical Research Information Sharing System, data and data pro-cessing were carried out (EHR 3000 between August 2011 and January 2013) into the database by ETL software. The MISCR (correlation between common symptoms and common syndromes) from both common symptoms and com-mon syndromes of AECOPD was analyzed with existing diagnosis standards of AECOPD. The comparative analysis on TCM syndromes such as heat phlegm obstructing the lung, lung and kidney qi deficiency, phlegm turbid obstructing the lung and their correspondent existing diagnosis standards of AECOPD showed that the common TCM syndromes in the clinic are the mixture of deficiency and excess syndromes. However, some individual symptom is contradicted to its correspondent syndrome. It was concluded that based on the Clinical Research Information Sharing System, the research on correlation analysis between syndromes and symptoms of AECOPD can provide strong evidence and methodology for the validation and revision of TCM diagnostic criteria.