RESUMO
Objective:To explore the e ects of clinical treatment and protection on endothelial function of early essential hypertension patients treated with YiNianJiangYa(YNJY) soup in southern Guangdong area.Methods:79 early essential hypertension cases with traditional Chinese medicine(TCM) syndrome of phlegm stasis blocking collaterals,excess of liver yang were randomly divided into treatment and control groups,treated with YNJY soup and TianMaGouTeng(TMGT) soup respectively for two courses of treatment.Di erences of clinical treatment e ect,blood pressure and pulse pressure after treatment,as well as plasma endothelin-1(ET-1) and von Willebrand factor(vWF) between the two groups were measured.Results:The clinical total e ective rate of treatment group was higher than that of control group(P 0.05).Conclusion:YNJY soup can signi cantly improve clinical treatment e ect of the early essential hypertension patients,has good e ect of decreasing blood pressure and no obvious side e ects.It has many e ects that reduces PP and the levels of plasma ET-1,vWF,may be related to protection of endothelial function,thereby improve the artery exibility.