RESUMO
Objective: To study the hypoglycemic effects of chromium-enriched compound acidophilous milk in rats with hyperglycemia. Methods: 120 adult Wister rats were randomly divided into Control group, DM group, therapy group and protective therapy group. Each group were fed a basic diet and Control group were intragastric administration with sodium chloride,DM group and therapy group were intragastric administration with ordinary acidophilous milk and protective therapy group were intragastric administration with chromium-enriched compound acidophilous milk. After 15 days, the rats of DM group, therapy group and protective therapy group were given a single shot of alloxan (50 mg per 1 kg), while Control group was given a single shot of sodium chloride (50 mg per 1 kg). After the diabetic model had been induced by alloxan,the rats of therapy group were intragastric administration with chromium-enriched compound acidophilous milk, and other groups had no change. The blood-fasting sugar, sugar tolerance, and glycosylated hemoglobin were examined. Results: When compared with protective therapy group, the differences of blood-fasting sugar of DM group and therapy group were significant (P