RESUMO
A doença de Graves neonatal é observada em baixa porcentagem de crianças nascidas de mães portadoras dessa doença. Pode ser grave, com risco de morte e com efeitos deletérios sobre o desenvolvimento neural, embora seja geralmente autolimitada. A maioria dos recém-nascidos com hipertireoidismo pode melhorar rapidamente, desde que a terapia adequada seja logo iniciada, o que evita lesões sobre o sistema nervoso. (AU)
The neonatal Graves 'disease refers to hyperthyroidism, which is observed in a small percentage of children born to mothers with this disease. Although neonatal Graves' disease is usually self-limited, can be severe, life-threatening, and harmful effects on neural development. With appropriate therapy, started immediately, most newborns with hyperthyroidism may have improved rapidly, avoiding the negative consequences of hyperthyroidism in the developing nervous system. (AU)
Assuntos
Humanos , Recém-Nascido , Tireotoxicose , Doença de Graves , HipertireoidismoRESUMO
Follicular adenoma is a benign encapsulated tumor with evidence of follicular cell differentiation. It is the most common thyroid neoplasm, usually solitary and has a well-defined fibrous capsule. We experienced a case of follicular adenoma occurring in congenital goiter and reported with the brief review of related literature
Assuntos
Adenoma , Diferenciação Celular , Bócio , Neoplasias da Glândula TireoideRESUMO
We experienced a case of congenital goiter with congenital hypothyroidism in 45 day-old male, who complained of respiratory difficulty and anterior neck mass. After admission, he was diagnosed congenital hypothyroidism by the clinical manifestations and laboratory tests including biochemistry, radioimmunoassay, radioisotope study, perchlorate discharge test, and bone radiography. We obtained positive finding at the perchlorate discharge test and found that his congenital goiter with congenital hypothyroidism was manifested by organification defect. We started treatment with L-thyroxine orally at 6th hospital day. The case was presented with brief review of literatures.