RESUMO
The effect of ethanol extract of whole plant of Cynoglossum zeylanicum on Oral Glucose Tolerance was determined. Ethanol extract of Cynoglossum zeylanicum were evaluated for Oral Glucose Tolerance Test (OGTT) in normal and alloxan induced diabetic rats. Oral administration of ethanol extract at doses of 100 &150mg/kg body weight shows that the extract promote glucose uptake. These results suggest that the ethanol extract of Cynoglossum zeylanicum whole plant will be useful in the treatment of impaired oral glucose tolerance.
RESUMO
The present study aims to evaluate the antitumor activity of ethanol extract of whole plant of Cynoglossum zeylanicum on DAL model in Swiss Albino mice. Evaluation of the antitumor effect of ethanol extract of whole plant of Cynoglossum zeylanicum on tumor growth and host survival time was made by the study of the following parameters: tumor volume, viable and non viable cell count and life span of host. The results showed decrease in tumor volume and cell viability. Hematological studies revealed that, the Hb count decreased in DAL treated mice, whereas, it was induced by the drug treated animals and showed an increase in Hb near to normal levels. The results suggested that, the extracts of whole plant of Cynoglossum zeylanicum exhibited significant antitumor activity on DAL bearing mice.