RESUMO
The historical circumstances about the application of the Japanese Kampo-medicine on the point of clinical view are the following that the original directions of the Chinese medical classics have been strictly adhered in China while the directions of those have been remarkably developed in Japan after the import. Now the Japanese Kampo-medecine are based upon these recent developments as well as the current pharmacological studies. Several clinical casereports are demonstrated who are treated with Daisaiko-to, Hachimijio-gan, and Hochuekki-to.<br>Finally the noteworthy opinions by Sensai Nagayo who laid the foundation of the medical system in modern Japan are quoted from his autobiography. Namely the really valuable new medicine should be established with the combination of both the western medicine and the Kampo-medicine.
RESUMO
We encountered three patients with schizophrenia diagnosed by DSM-III-R and/or ICD-9, all of whom improved significantly with Daisaiko-to. Psychiatric presentations evident were irritability, face-to-face tension and agitation, and constipation was present a somatic disturbance.<br>The psychiatric symptoms were associated with anger, the specific emotion corresponding to the orbis hepaticus, based on the Five Evolutive Phases (wu-hsing). Therefore, these symptoms were thought to be caused by dysfunction of Liver Ki (Qi) (energetic configuration). Daisaiko-to was prescribed in order to improve the function of Liver Ki based on the concept that the disorder was related to Kankao (a flaming up of Liver Fire). The effectiveness of this formula suggested that both Bupleuri Radix and Raeoniae Radix, which are components of Daisaiko-to, were important herbal drugs to alleviate “flaming up of the Liver Fire, ” in the treatment of schizophrenia.