A cross-sectional study to determine the cognitive impairment and depression among elderly in a rural area of West Bengal

Background: The increase in worldwide life expectancy among the elderly is contributing to an increase in cognitive impairment (CI). A more complicated etiology makes CI an essential clinical concern for elderly patients with depression. Ageing populations as a result of demographic change have accelerated the development of certain geriatric conditions, including CI and depression. Aims and Objectives: The objective was to identify the prevalence and contributing factors of CI and depression in the elderly rural community. Materials and Methods: A descriptive, cross-sectional, and community-based study was conducted in rural field practice area of Medical College, Kolkata, among 133 geriatric people during time period of March–June, 2022. The prevalence of CI was measured using the Mini-Mental State Examination (MMSE) scale and depression was assessed using the geriatric depression scale. Data were analyzed in SPSS software version 16. Results: Mean age of the participants was 65.68 (±6.03) years. The prevalence of CI was 86.5%, with a mean MMSE score of 19.27 ± 4.34, and the depression was 77.5% and 7.07 ± 3.39. Conclusion: Almost two-third of the geriatric population is suffering from depression and CI. To handle the issue of CI, depression, and its resulting effects, new and modified geriatric health policies are very much needed.

Governor vessel moxibustion combined with western medication for mild to moderate depression with kidney-yang deficiency: a randomized controlled trial / 中国针灸

OBJECTIVE@#To compare the therapeutic efficacy of governor vessel moxibustion combined with fluoxetine hydrochloride capsule, simple fluoxetine hydrochloride capsule and placebo moxibustion combined with fluoxetine hydrochloride capsule for mild to moderate depression with kidney-yang deficiency.@*METHODS@#A total of 126 patients with mild to moderate depression with kidney-yang deficiency were randomized into a governor vessel moxibustion group (42 cases, 2 cases dropped off), a western medication group (42 cases, 1 case dropped off) and a placebo moxibustion group (42 cases, 1 case dropped off). The western medication group was given fluoxetine hydrochloride capsule orally, 20 mg a time, once a day. On the basis of the treatment in the western medication group, governor vessel moxibustion was applied from Dazhui (GV 14) to Yaoshu (GV 2) in the governor vessel moxibustion group, once a week; placebo moxibustion was applied in the placebo moxibustion group, once a week. Treatment of 8 weeks was required in the 3 groups. Before and after treatment, the scores of Hamilton depression scale-17 (HAMD-17), Asberg's rating scale for side effects (SERS) and TCM clinical symptom were compared, and the clinical efficacy was evaluated.@*RESULTS@#After treatment, the scores of HAMD-17, SERS and TCM clinical symptom were decreased compared before treatment in the 3 groups (P<0.05), the decrease ranges of above scores in the governor vessel moxibustion group were larger than those in the western medication group and the placebo moxibustion group (P<0.05). The total effective rate was 92.5% (37/40) in the governor vessel moxibustion group, which was higher than 75.6% (31/41) in the western medication group and 80.5% (33/41) in the placebo moxibustion group (P<0.05).@*CONCLUSION@#Governor vessel moxibustion combined with fluoxetine hydrochloride capsule can improve the degree of depression and relieve the clinical symptoms in mild to moderate depression patients with kidney-yang deficiency, the efficacy is superior to simple fluoxetine hydrochloride capsule, and can reduce the fluoxetine hydrochloride capsule-induced adverse effect to a certain extent.

Therapeutic effects of Tongdu Qishen acupuncture combined with traditional Chinese medicine decoction on post-stroke depression in 31 patients / 中国基层医药

Objective:To investigate the clinical effects of Tongdu Qishen acupuncture combined with traditional Chinese medicine decoction on post-stroke depression in patients. Methods:Sixty-two patients with post-stroke depression who received treatment in Zhongda Hospital of Southeast University from October 2020 to April 2022 were included in this study. They were randomly treated either with traditional Chinese medicine decoction (control group, n = 31) or Tongdu Qishen acupuncture combined with traditional Chinese medicine decoction (combined group, n = 31) based on routine medication. All patients were treated for 4 weeks. Depressive state, neurological function, and activities of daily living were compared between the two groups. Results:Before treatment, there were no significant differences in the Hamilton Depression Scale (HAMD) score, National Institutes of Health Stroke Scale (NIHSS) score, and Barthel index between the two groups (all P > 0.05). After 4 weeks of treatment, the HAMD and NIHSS scores in the control group were (13.88 ± 3.92) points and (8.56 ± 1.82) points, respectively, and they were (8.72 ± 2.48) points and (6.67 ± 1.14) points in the combined group. There were significant differences in HAMD and NIHSS scores between the two groups ( t = 2.14, 2.43, both P < 0.05). The Barthel index in the combined group was (69.53 ± 13.29) points, which was significantly higher than (62.34 ± 15.67) points in the control group ( t = 2.23, P < 0.05). Conclusion:Tongdu Qishen acupuncture combined with traditional Chinese medicine decoction can reduce depressive symptoms and improve neurological function and activities of daily living in patients with post-stroke depression. The combined therapy has obvious efficacy in the treatment of post-stroke depression.

An analytical cross-sectional study on the association between animal companionship and anxiety among students of a private medical school in Quezon City / The Health Sciences Journal

Introduction@#Constant stress predisposes medical students to anxiety. The study aimed to determine the association between animal companionship and anxiety among medical students at UERMMMCI.@*Methods@#The study utilized an analytical cross-sectional design via an online form with the anxiety portion of the HADS questionnaire. Participants included first to third year medical students of a private medical school.@*Results@#A total of 161 responses were recorded. Sex and year-level exhibited significant association with anxiety. Those with anxiety were 2.71 times more likely to be females (p = 0.007). Stratification showed that those with anxiety were 1.72 times less likely to be females with pets (p = 0.37) while, in contrast, those with anxiety were 3.64 times more likely (p = 0.02) to be males with pets. Those with anxiety were likely to belong to first and second-years (p = 0.01 and p = 0.06), respectively and pet owners, though, not statistically significant (p = 0.357).@*Conclusion@#An association between sex and year-level with anxiety was noted. Those with anxiety were likely to be females, first-years, and males with animal companionship. Although they did not reach statistical significance.

Postpartum Depression and its Clinico-Social Correlates – A Community-Based Study in Aligarh

Context: Postpartum depression (PPD) is onset of depressive symptoms in postpartum period from 2 weeks to 1 year. It causes maternal morbidity and long?term negative effects on growth and development of infant and child. It is often unreported and underdiagnosed. Aims: (1) To estimate the prevalence of PPD,(2) To determine socio?demographic, clinical, and obstetric correlates of the same. Settings and Design: A cross-sectional study was done in urban and rural areas of District Aligarh. Methods: A total of 304 females between 6 weeks and 6 months’ postpartum period giving consent were included in this study. Sociodemographic, obstetric, and clinico-social factors were recorded using predesigned, pretested questionnaire. Edinburgh Postnatal Depression Scale (EPDS) score ?10 was used to screen for PPD and International Classification of Disease (ICD?10) criteria for confirmation. Statistical Analysis Used: Correlates of PPD were determined using logistic regression analysis. Results: The prevalence of PPD was 9.5% using EPDS and was confirmed by ICD?10 criteria. History of abortion (adjusted odds ratio [AOR]: 6.0, 95% Confidence Interval [CI] 2.2–16.5), poor relationship with in?laws(AOR: 5.1; 95% CI 1.3–20.5), marital conflict (AOR: 13.3; 95% CI 2.2–77.6), and substance abuse in husband (AOR: 3.1; 95% CI 1.1–9.0) were found to be significant correlates for PPD. Conclusions: About one in every 10 postpartum females suffered from depression but did not seek health care for the same. Women facing social pathologies such as substance abuse in husband, marital conflict, and poor relationship with in?laws are more at risk of PPD. Screening for PPD should be included in the maternal and child health care programs to ensure early diagnosis and treatment.

Antenatal depression and its correlates - a cross-sectional study in an urban resettlement colony of Delhi

Background- Antenatal depression is affecting 10% pregnant women worldwide with higher prevalence in developing countries. This causes poor maternal and foetal outcome and also affects cognitive development of the child. Aim and objective: To estimate magnitude of antenatal depression and its risk factors. Methodology- A cross-sectional survey was done at the antenatal clinic of community health department catering to an urban resettlement colony, East Delhi. Estimated sample size was 216 (including 10% non-response rate). Pregnant women attending the ANC clinic from October 2019 to February 2020 were enrolled. EPDS questionnaire was used to assess depression during pregnancy. Results-The antenatal depression was found in 11.8% subjects as per EPDS score. Working female and belonging to Muslim religion, past history of abortion, complications in previous pregnancy, financial debt, physical violence and substance use in family showed significant association with antenatal depression. Conclusion –Depression was prevalent among antenatal women and was found to be associated with various risk factors.

Depression in the elderly: Prevalence and associated factors in urban population

Introduction: Depression in elderly population is a serious public health concern but is often undetected and ignored as a medical problem, leading to poor quality of life. Aim and Objectives: The objectives of this study were to estimate the prevalence and degree of depression among the elderly population using a Geriatric Depression Scale (GDS?15) Short Form and to study some correlates associated with depression in them. Materials and Methods: A community-based cross-sectional study was conducted with a sample size of 100 elderly subjects using systematic random sampling technique. After getting informed consent, information was collected using GDS?15 Marathi version. Results: Of 100 respondents interviewed, 52 were 70 years and above and 54 were male. The prevalence of depression among the elderly was 84.0%. Sixteen (8 males and 8 females) were suffering from severe depression. Age, sex, death of spouse, education, occupation, and morbidity status were found to be significantly associated with depression. Conclusions: The prevalence of depression among the urban elderly was very high. By identifying risk factors for depression among the elderly population and screening them on time, we can go a long way in adding life to their years instead of years to life of the elderly.

Anxiety and depression among medical undergraduate students and their sociodemographic correlates in Sikkim: A cross-sectional study

Background: Psychological morbidity in medical undergraduate students has always been reported from various countries across the globe. Studies which document this burden among medical students in India are very few. Aims and Objectives: The presence of depression and anxiety among medical undergraduate students was assessed using a previously validated and standardized instrument, hospital anxiety and depression scale (HADS) and the associations with their sociodemographic and comorbidities were identified. Materials and Methods: In a cross-sectional survey, a self-administered, pre-designed, pre-tested HADS was used to collect information on basic sociodemographic (age, gender, semester, and socioeconomic status) and comorbidities through a Google Forms. Informed written consent was obtained from all participants. Scores for each of the respondents over each of the subscales (depression and anxiety) were calculated as per the severity rating index. Results: The study showed that majority (77.4%) of the students did not feel that they were depressed which was found to be similar in both male and female students. However, about 50% of both male and female students were found to be suffering from either mild or moderate anxiety. The present study showed that there was no significant association between HADS score and socioeconomic and sociodemographic characteristics among medical undergraduate students. Conclusion: A substantial proportion of medical undergraduate students was found to be anxious and quite a lot of them were found to be suffering from mild to moderate depression, revealing a neglected area of the students’ psychology requiring urgent attention. Student counseling services need to be made available and accessible to curb this morbidity.

Statistical Validation of LENS: A Smartphone-based Empty Nest Syndrome Screening and Monitoring Biomarker Tool

Background: Empty Nest Syndrome (ENS) is a complex grief state, observed in the affected parents when their children leave home. Studies show ENS may progress to clinical-grade depression and anxiety if left uncared for. Methodology: In this double-blind case-control cross-sectional study, 80 subjects are recruited by a panel of psychologists and psychiatrists. Subjects are divided into two equal groups – case (with ENS symptoms) and control (without symptoms). Three instruments are applied – a) ENS interpretation by the psychologists based on the symptoms, b) Lyfas smartphone-based biomedical application to capture the cardiovascular optical biomarkers (COB) from the index finger non-invasively with the help of arterial photoplethysmography technique, and c) Hamilton’s depression scales (HAM-D), which psychiatrists have used to check the mental health of the subjects. The COB (e.g., SD1/SD2, LF/HF, HRVScore, and ENERGY) and a set of physical parameters (e.g., Body mass index or BMI, Heart rate or HR, Systolic blood pressure or SBP, Diastolic blood pressure or DBP, Glycosylated hemoglobin or HbA1c, Cholesterol, Triglyceride, Thyroid-stimulating hormone or TSH, Estradiol or E2, and Testosterone or TST) consist the independent variables, while ENS scores interpreted by the psychologists and HAM-D scores interpreted by the psychiatrists are the dependent variables. Spearman’s rank correlation and Bland Altman’s reliability tests are performed to mine the significant independent variables and reliability of Lyfas ENS (LENS) application. Results: The study observes that SD1/SD2, LF/HF, HRVScore, ENERGY, DBP, BMI, HR, HbA1c, TSH, and Estradiol have significant roles in ENS. Bland Altman's reliability measure shows that LENS (novel instrument under trial) has a high agreement of 92.85% and 93.86%, respectively with ENS scoring done by senior psychologists (champion instrument1) and HAM-D grading performed by psychiatrists (champion instrument2). Conclusions: LENS can be used as a clinical-graded pocket application for screening and monitoring ENS.

DEPRESSION STATUS AMONG THE FEMALES DURING THE FIRST POSTPARTUM PERIOD AT CLINICAL SETTINGS OF PRIMARY HEALTH CARE CENTRES IN ARAR CITY, SAUDI ARABIA.

Background: Postpartum depression is one of the most common, but often unrecognized, complications of childbirth and is considered as a serious psychological disorder that can affect women during or after birth and during pregnancy. Its risk increases during the ?rst 90 days and can last up to nearly two years. Objectives: To determine the prevalence of postpartum depression (PPD) and correlate it with variables of obstetric and demographic predictors among females attending primary health care centres in Arar city. Methodology: This was a cross-sectional study carried out by using Arabic version of questionnaire of Edinburgh Postnatal Depression Scale (EPDS) tool during the study period from August to September 2021. A total of 383 sample was taken by using convenience sampling method. Analysis was done by using Statistical Package for Social Sciences. Results: The prevalence of postpartum depression was 30.5%. Multiple associated factors were found to be signi?cantly increase the risk of PPD such as: females who had caesarean section delivery, unplanned pregnancy, complicated pregnancy, their baby had medical problem and had no or less husband support, had psychiatric disorders, had chronic medical problem, taking chronic medication, had life stressor, low education and low income (P < 0.05). The results of the logistic regression analysis showed that the odds of PPD signi?cantly increase in females had caesarean section delivery compared to vaginal delivery (P = .002), females had rare support from the husband (P = .002), females had psychiatric disorders (P = 0.016) and had life stressor (P = .000). Conclusions: The prevalence of postpartum depression in the city of Alar was clearly high. Our study also showed important predictors that could be used to identify high-risk females. It is advisable to provide social support to females during both prenatal and postnatal periods. Regular screening of women for postpartum depression should be encouraged for early detection and prompt intervention

Efficacy of combined fluoxetine and aniracetam tablets in the treatment of senile depression and its effects on serum total bile acid and norepinephrine levels / 中国基层医药

Objective:To investigate the efficacy of combined fluoxetine and aniracetam tablets in the treatment of senile depression and its effects on serum total bile acid (TBA) and norepinephrine (NE) levels.Methods:A total of 100 older adult patients with depression who received treatment in Heze Medical College from January 2019 to December 2019 were included in this study. They were randomly assigned to receive either fluoxetine tablets alone (control group, n = 50) or fluoxetine and aniracetam tablets (study group, n = 50). All patients received two months of treatment. Clinical efficacy, scores of the Hamilton Rating Scale for Anxiety (HAMA) and the Hamilton Rating Scale for Depression (HAMD), adverse reactions, and serum TBA and NE levels were compared between the two groups. Results:Total response rate was significantly higher in the study group than in the control group [96.0% (48/50) vs. 84.0% (42/50), χ2 = 4.00, P = 0.045]. HAMD and HAMA scores post-treatment in the study group were (5.85 ± 1.81) points and (4.81 ± 1.57) points, respectively, which were significantly lower than those in the control group [(11.65 ± 2.65) points, (10.85 ± 2.84) points, t = 10.84, P < 0.001; t = 11.16, P < 0.001). Serum NE level was significantly higher in the study group than in the control group [(138.68 ± 16.35) ng/L vs. (127.17 ± 14.34) ng/L, t = 3.17, P = 0.002]. There were no significant differences in serum TBA level [(5.85 ± 0.63) μmol/L vs. (5.91 ± 0.65) μmol/L] and the incidence of adverse reactions (8.00% vs. 6.00%) between the study and control groups ( t = 0.39, P = 0.692; χ2 = 0.15, P = 0.695). Conclusion:The combined therapy of fluoxetine and aniracetam tablets for the treatment of senile depression is safe and highly effective, does not affect metabolic function and thereby deserves clinical application.

Effects of repetitive transcranial magnetic stimulation combined with oral paroxetine on cognitive status and activities of daily living in older adult patients with severe depression / 中国基层医药

Objective:To investigate the efficacy of repetitive transcranial magnetic stimulation (rTMS) combined with oral paroxetine in the treatment of older adult patients with severe depression and its effects on the scores of the Hamilton Rating Scale for Depression (HAMD), the Mini-Mental State Examination (MMSE), and Activities of Daily Living (ADL).Methods:A total of 192 older adult patients with severe depression who received treatment in Shaoxing 7 th People's Hospital from January 2018 to December 2019 were included in this study. They were randomly assigned to receive either oral paroxetine (control group, n = 96) or rTMS + oral paroxetine (observation group, n = 96). All patients received 1 month of treatment. Clinical efficacy was compared between the two groups. HAMD, MMSE, and ADL scores pre- and post-treatment and the incidence of adverse events during the treatment were compared between the two groups. Results:Total response rate was significantly higher in the observation group than in the control group [96.88% (93/96) vs. 89.58% (86/96), χ2 = 4.04, P < 0.05]. HAMD scores post-treatment were significantly lower in the observation group than in the control group [(6.43 ± 2.33) points vs. (11.32 ± 2.02) points, t = 15.53, P < 0.05]. MMSE and ADL scores post-treatment in the observation group were (29.13 ± 3.01) points and (71.52 ± 5.32) points, respectively, which were significantly higher than those in the control group [(24.65 ± 2.79) points, (69.65 ± 5.17) points, t = 10.69, 2.47, P < 0.05]. There was no significant difference in the incidence of adverse events between the two groups ( P > 0.05). Conclusion:The combined therapy of rTMS and oral paroxetine is highly effective on severe depression in older adult patients. It can improve cognitive function and the activities of life living.

The effect of eCASH model on negative emotion and risk of related adverse events in patients with severe continuous renal replacement therapy / 中国实用护理杂志

Objective:To investigate the effects of early Comfort using Analgesics, minimal Sedatives and maximum Humane care (eCASH) patterns on the risk of negative mood and continuous renal replacement therapy (CRRT)-related adverse events in patients with severe CRRT.Methods:A total of 90 patients with severe CRRT in Shenzhen Integrated Traditional Chinese and Western Medicine Hospital from October 2018 to October 2020 were selected as the study subjects, and they were divided into observation group and control group according to random number table method, with 45 patients in each group. The control group was given routine nursing program, and the observation group was given eCASH mode on the basis of the control group.Nursing satisfaction, CRRT-related adverse events and negative mood scores before and after nursing were compared between 2 groups.Results:The nursing satisfaction degree of the observation group was 86.67% (39/45), significantly higher than that of the control group (66.67%, 30/45), and the difference was statistically significant ( χ2=5.03, P<0.05). After nursing, the Hospital Anxiety and Depression Scale-Anxiety(HADS-A) and Hospital Anxiety and Depression Scale-Depression(HADS-D) scores of the observation group were 5.18 ± 0.67 and 5.27 ± 0.61, respectively, lower than 8.14 ± 1.18, 7.94 ± 1.07 before intervention, and 6.33 ± 0.72, 5.94 ± 0.49 of the control group. Barthel Index(BI) (65.17 ± 8.67) was significantly higher than that before nursing 41.56 ± 6.46 and control group 60.48 ± 6.47, the difference was statistically significant ( t values were 5.74-20.76, all P<0.05). The scores of Visual Analogue Scale(VAS), Present Pain Intensity(PPI), sensory total score and emotional total score of observation group after nursing were 3.24 ± 0.56, 1.18 ± 0.25, 6.38 ± 0.89, 2.68 ± 0.59 significantly lower than those before nursing 6.24 ± 0.87, 3.24 ± 0.56, 11.24 ± 1.81, 6.37 ± 1.04 and 4.36 ± 0.67, 1.31 ± 0.31, 7.26 ± 0.96, 2.98 ± 0.62 of the control group. The difference was statistically significant ( t values were 2.19-20.70, P<0.05). Conclusions:eCASH model can significantly improve the negative emotions of patients with severe CRRT, improve their comfort and reduce the risk of related adverse events, which is worthy of clinical promotion.

Investigation on anxiety, depression and sleep quality in primary glaucoma / 国际眼科杂志(Guoji Yanke Zazhi)

@#AIM: To investigate the anxiety, depression and sleep status of patients with primary angle-closure glaucoma(PACG)and primary open angle glaucoma(POAG).<p>METHODS: Retrospective clinical study. The Anxiety Self-Rating Scale(SAS), Depression Self-Rating Scale(SDS)and Pittsburgh Sleep Quality Index(PSQI)were used to evaluate 60 patients with primary glaucoma(30 PACG, 30 POAG)diagnosed in the department of ophthalmology in our hospital during the period from June 2019 to December 2020 and 30 healthy adults from the physical examination department of our hospital as a control group. The scores of anxiety, depression and sleep quality in the three groups were compared.<p>RESULTS: The scores of SAS, SDS and PSQI in PACG and POAG groups(48.40±9.302, 53.40±8.625, 9.57±2.861; 42.57±9.684, 48.80±10.320, 7.23±2.223)were significantly higher than those in control group(37.03±6.805, 38.63±7.881, 4.87±2.688)(<i>P</i><0.05). The scores of SAS and PSQI in PACG group were higher than those in POAG group(all <i>P</i><0.05). With SAS≥45, SDS≥50 and PSQI>7, the positive rates of anxiety, depression and insomnia in the PACG group(77%, 73%, 70%)were higher than those in the POAG group(43%, 40%, 37%)and the control group(13%, 10%, 20%)(<i>P</i><0.05).<p>CONCLUSION: Patients with PACG has more severe anxiety, depression and insomnia than POAG, so necessary psychological intervention should be given.

Intestinal microbiome changes in patients with postpartum depression / 西安交通大学学报(医学版)

【Objective】 To analyze the changes of gut microbes in patients with postpartum depression so as to explore the relationship between postpartum depression and gut microbes. 【Methods】 A total of 60 postpartum subjects were recruited to participate in this study. The depression status of the participants was scored using the Edinburgh Postpartum Depression Scale (EPDS). Those with a score ≥13 were included in the postpartum depression group (PPD group), while those with a score less than 13 were included in the postpartum healthy control group (PPHC group). The feces of these 60 subjects were collected, and the fecal whole genome DNA was extracted for 16S rDNA sequencing. The data of changes in the bacterial diversity between the groups were obtained, and the possible correlation between the changes of intestinal microbes and postpartum depression was analyzed. 【Results】 The number of microorganisms in PPD patients was significantly reduced (P<0.001); the Chao1 index (P<0.001) and ACE index (P<0.001) of α diversity decreased significantly. There were also significant differences in β diversity between the two groups. Analysis of the bacteria in the groups showed that Acetanaerobacterium, Adlercreutzia, Allobaculum, Alloprevotella, Bifidobacterium, Christensenella, Escherichia, Eubacterium, Faecalicatena, Fusobacterium, Haemophilus, Intestinimonas, Lactobacillus, Megamonas, Monoglobumus, Muribaculum, Oscillospira, Paraprevotella, Streptococcus, Raoultibacter, Ruminococcus and Stomatobaculum were significantly enriched in PPHC group. In contrast, Kineothrix, Lachnoclostridium, Acinetobacter, Aquisphaera, Enterococcus, and Mucispirillum were enriched in PPD group. RDA/CCA analysis showed that EPDS was positively correlated with Prevotella, Kineothrix, and Alistipes, but negatively correlated with Lachnospira. 【Conclusion】 This study found that the intestinal flora of patients with postpartum depression was significantly disrupted, and there was a correlation between the intestinal flora and postpartum depression symptom score. Therefore, intestinal microbial markers may contribute to the diagnosis and treatment of patients with postpartum depression.

Structural Differences of Depression for Patients with Parkinson's Disease Using Hamilton Depression Scale / 中国康复理论与实践

Objective:To explore the structural differences and the trend in series scores of Hamilton Depression Scale (HAMD) in patients with Parkinson's disease (PD). Methods:From June, 2017 to March, 2018, 168 PD patients from Beijing Tiantan Hospital were reviewed. Their genders, ages, courses of disease, Hamilton Depression Scale (HAMD) scores, unified Parkinson's disease rating scale III (UPDRS III) scores，Hoehn-Yahr stage and Mini-Mental State Examination (MMSE) scores, the most improvement ratios by PD drug and other clinical data were collected. The patients were divided into non-depression group (n = 61), mild depression group (n = 68) and moderate depression group (n = 39) according to the HAMD scores. The series scores of HAMD among the groups were compared. Results:The factor scores all increased with depression exacerbating (F > 10.546, P < 0.001), except day and night change in the mild depression group, while the proportion of anxiety/somatization score decreased, and the proportion of cognitive disorder and retardant scores increased. Conclusion:The depression structure changes in PD patients with depression exacerbating, which means decrease of anxiety/somatization and increase of cognitive disorder and retardant.

Effects of structured group psychotherapy on symptoms and social function of patients with mild to moderate depression / 中国基层医药

Objective:To investigate the effects of structured group psychotherapy on symptoms and social function of patients with mild to moderate depression.Methods:Sixty patients with mild to moderate depression who received treatment in Department of Psychiatry of the Third People's Hospital of Yongkang from June 2019 to May 2020 were included in this study. They were randomly assigned to receive either conventional antidepressants ( n = 30, control group) or conventional antidepressants combined with structured group psychotherapy ( n = 30, observation group). The Self-rating Anxiety Scale, Self-rating Depression Scale Hamilton Anxiety Scale, Hamilton Depression Scale and the Simplified Coping Style Questionnaire were used to compare the anxiety state, depression state and coping style between the two groups. Results:Self-rating Anxiety Scale, Self-rating Depression Scale, Hamilton Anxiety Scale, Hamilton Depression Scale and Simplified Coping Style Questionnaire scores in the observation group were (44.21 ± 4.15) points, (45.28 ± 5.16) points, (12.41 ± 2.16) points, (9.75 ± 2.83) points, and (10.35 ± 2.23) points, respectively, which were significantly lower than those in the control group [(51.14 ± 4.39) points, (53.64 ± 5.31) points, (16.73 ± 2.54) points, (14.18 ± 2.72) points, (14.73 ± 2.54) points, t = 6.283, 6.184, 7.097, 6.182, 7.375, all P < 0.001]. Simplified Coping Style Questionnaire score in the observation group was significantly higher than that in the control group [(31.42 ± 4.43) points vs. (24.16 ± 4.27) points, t = 7.432, P < 0.001]. Conclusion:Structured group psychotherapy combined with conventional antidepressant therapy for treatment of mild to moderate depression can greatly reduce the symptoms of anxiety and depression and improve the coping style.

Mild and moderate postpartum depression treated with acupuncture of / 中国针灸

OBJECTIVE@#To observe the clinical therapeutic effect on mild and moderate postpartum depression treated with acupuncture of @*METHODS@#A total of 116 patients with mild and moderate postpartum depression were divided into an acupuncture group (103 cases) and a non-acupuncture group (13 cases) according to treatment regimen provided. In the acupuncture group, acupuncture of @*RESULTS@#The total effective rate of the acupuncture A group was 100.0% (31/31), better than 76.9% (10/13) in the non-acupuncture group and 58.1% in the acupuncture B group (18/31) (@*CONCLUSION@#Acupuncture of

Measurement of anxiety and depression among cancer patients seen in an outpatient clinic of a tertiary hospital using the validated Hospital Anxiety and Depression Scale – Pilipino Version (HADS-P)

Background@#Anxiety and depression, two of the most common affective disorders in cancer patients can affect one’s compliance to treatment leading to poorer outcomes. Therefore, means of determining the psychological wellness of cancer patients through screening tools for anxiety and depression are an integral part of their management.@*Objectives@#1) To measure the prevalence of anxiety and depression among cancer patients seen in an outpatient clinic of a tertiary hospital using the HADS-P. 2) To assess the impact of the following variables on symptoms of anxiety and depression: demographic, socio-economic, biological and health/clinical parameters.@*Methodology@#This is a cross-sectional analytic study involving 381 cancer patients seen in the outpatient clinic. Symptoms of anxiety and depression were measured using the HADS-P with an 11+ cut-off to identify possible cases of anxiety and depression. Univariate analysis, using STATA Version 13, was performed to identify correlates of anxiety and depression.@*Results@#The prevalence of anxiety, depression and mixed diagnosis (anxiety and depression) amongst this study population were 9.45%,4.72% & 2.89%, respectively. The multivariate analysis described non-college graduates (OR=1.82, CI 0.80-4.14), poor performance status (ECOG 2-3) (OR=5.34, CI 2.44-11.71) and the newly diagnosed and with ongoing treatment patients (OR= 12.02, CI 2.67-54.04 and OR=4.04, CI 0.88-18.58, respectively) as possible correlates of anxiety. Patients with poor performance status and have moderate-severe pain were likely to experience depression (OR= 6.14, CI 2.14-17.62; OR= 2.78, CI 0.92-8.46, respectively).@*Conclusions@#There are several factors that can affect one’s predisposition to having affective disorders. Clearly, there is a necessity to allocate resources for screening and treating affective disorders among cancer patients to improve their compliance, to achieve a more holistic approach in their management and ultimately, to improve their quality of life.

Prevalencia de depresión posparto y factores asociados en usuarias de un hospital público de Acapulco, Guerrero, México / Prevalence of postpartum depression and its associated factors in users of a public hospital at Acapulco, Guerrero, Mexico

Resumen OBJETIVO: Estimar la prevalencia de depresión posparto y los factores asociados en usuarias del Hospital General Progreso, Acapulco, Guerrero, México. MATERIALES Y MÉTODOS: Estudio prospectivo, observacional y transversal de serie de casos. El instrumento para medir la depresión fue un cuestionario que incluyó la Escala de Depresión Posnatal de Edimburgo (EPDS por sus siglas en inglés). Además, a las pacientes se les preguntaron sus datos sociodemográficos, antecedentes de control prenatal, historial obstétrico, atención del parto y otros datos relacionados con su pareja. Mediante análisis bivariado y multivariado se estimaron los factores asociados con la depresión posparto. RESULTADOS: Se analizaron 485 pacientes con media de edad de 24.6 años y límites de 14 y 43 años. La prevalencia de depresión posparto fue de 16%. En el modelo final del análisis multivariado los factores asociados con la depresión posparto fueron: complicaciones en el parto (IC95%:1.61-6.54), antecedente de alcoholismo antes del embarazo (IC95%:1.17- 3.30) y recibir apoyo emocional del esposo durante el embarazo (IC95%: 0.17-0.68). CONCLUSIONES: El antecedente de consumo de bebidas alcohólicas, previo al embarazo, y tener alguna complicación del parto, fueron indicios de posible aparición de depresión posparto. Quienes la padecieron tuvieron la referencia temprana a los servicios de Psicología. La pareja debe estar informada que su apoyo emocional ayuda a reducir el riesgo de depresión posparto en la paciente.

Abstract OBJECTIVE: To estimate the prevalence of postpartum depression and associated factors in users of the Hospital General Progreso, Acapulco, Guerrero, Mexico. MATERIALS AND METHODS: Prospective, observational, cross-sectional case series study. The instrument to measure depression was a questionnaire that included the Edinburgh Postnatal Depression Scale (EPDS). In addition, patients were asked about their sociodemographic data, prenatal control history, obstetric history, delivery care and other data related to their partner. Factors associated with postpartum depression were estimated by bivariate and multivariate analyses. RESULTS: We analyzed 485 patients with a mean age of 24.6 years and cut-offs of 14 and 43 years. The prevalence of postpartum depression was 16%. In the final multivariate analysis model, the factors associated with postpartum depression were: delivery complications (CI95%:1.61-6.54), history of alcoholism before pregnancy (CI95%:1.17- 3.30) and receiving emotional support from husband during pregnancy (CI95%: 0.17-0.68). CONCLUSIONS: A history of alcoholic beverage consumption prior to pregnancy and having some complication of childbirth were indicative of possible occurrence of postpartum depression. Those who suffered from it had early referral to psychology services. The couple should be informed that their emotional support helps to reduce the risk of postpartum depression in the patient.