Differentiation of Desmoplastic Spitz Nevus from Similar Conditions / 대한피부과학회지

No abstract available.

Disappearing Atypical Lentiginous Pigmentation of the Desmoplastic Malignant Melanoma

A 38-year-old man presented with a black pigmented patch overlying his upper lip, a part of the gingiva and the hard palate. An intradermal tumor mass was palpated at the central portion of the pigmented patch of the upper lip. Diphenylcyclopropenone (DPCP) is a potent contact sensitizer that could stimulate non-specific immunity. We report a case of desmoplastic malignant melanoma (DMM) in which an atypical lentiginous pigmentation disappeared with topical DPCP immunotherapy and the dermal tumor mass was removed by a surgical wedge-shaped excision. Though an atypical lentiginous pigmentation of DMM sometimes undergoes extensive spontaneous regression, in our case it could be attributed to the therapeutic effect of topical DPCP immunotherapy rather than a spontaneous regression.

Condyloma Acuminata Treated with Combination Therapy of Electrodessication and Applying Trichloroacetic Acid

There are many methods to treat condyloma acuminata (CA) such as physical destruction or immunotherapy, but they are not always satisfactory, especially when the lesions occur in young children or infants. Two patients, who showed CA on their anal region, were treated by combination therapy of ED and applying TCA, and were evaluated on the efficacy of the therapeutic method. Clinically and pathologically proven CA was treated with a simple combination method. First, the wart lesions were carefully electrodessicated and swept away, After that, 30% trichloroacetic acid was applied to eroded area. Clinical examination was performed periodically after treatment. Elimination of the CA was successful by one procedure. Complication was not found after treatment.There was no recurrence 1 year later at least. The combination therapy of ED and applying TCA seems to be a very simple, convenient and effective method.

A Case of Desmoplastic Malignant Melanoma

Desmoplastic malignant melanoma (DMM) is an uncommon variant of malignant melanoma featuring a proliferation of spindle cells with pronounced desmopaasia. DMM commonly occurs on the sun-damaged skin such as head and neck in older persons, and it can be associated with lentigo maligna. We report an unusual case of desmoplastic malignant melanoma that developed de novo on the trunk in a young patient.