Reliability of measurements taken from panoramic radiographs for automated sex determination / Confiabilidade das medições obtidas em radiografias panorâmicas para determinação automatizada do sexo

Introduction: forensic anthropology currently serves as a potent tool in primary and secondary identification, especially in mass disasters, increasingly common in our society. Objective: Verify the reproducibility of measured measurements. Proposes methods of personal identification. Method: to verify the reliability of the method, 25 radiographs were selected, the intra-class coefficient (ICC) and the Bland-Altiman statistical technique were calculated. accuracy of the method, was used. R studio and Medcalc were used. Results: The ICC was above 0.90 for all measurements. According to the Bland-Altman analysis, the average differences observed between examiners ranged from 0.017 (m5) to 0.020 (m7). These results highlight the reliability of measurements made by two different examiners performing the same tasks. Conclusion: The variables used in this study have shown satisfactory reproducibility. Thus, the selected and evaluated data can be used as metadata in automating the sex determination process from panoramic radiographs.

Introdução: A antropologia forense atualmente serve como uma ferramenta potente na identificação primária e secundária, especialmente em desastres em massa, cada vez mais comuns em nossa sociedade. Objetivo: Verificar a reprodutibilidade das medidas mensuradas. Propõe métodos de identificação pessoal. Método: para verificar a confiabilidade do método, foram selecionadas 25 radiografias, calculando-se o coeficiente intraclasse (ICC) e a técnica estatística de Bland-Altiman. Para avaliar a precisão do método, foram utilizados o R studio e o Medcalc. Resultados: O ICC foi superior a 0.90 para todas as medições. De acordo com a análise de Bland-Altman, as diferenças médias observadas entre os examinadores variaram de 0.017 (m5) a 0.020 (m7). Esses resultados destacam a confiabilidade das medições feitas por dois examinadores diferentes realizando as mesmas tarefas. Conclusão: As variáveis utilizadas neste estudo mostraram reprodutibilidade satisfatória. Assim, os dados selecionados e avaliados podem ser usados como metadados na automação do processo de determinação do sexo a partir de radiografias panorâmicas

Evaluation of the mandibular notch angle in three-dimensional virtual models as a parameter for determining age and sexual dimorphism / Avaliação do ângulo da incisura mandibular em modelos virtuais tridimensionais como parâmetro para estimativa de idade e dimorfismo sexual

Objective: The objective of this study was to analyze the opening of the mandibular notch angle (MNA) as a possible tool for predicting sex and estimating age so as to contribute to forensic anthropological studies. Material and Methods: For this, 60 cone beam computed tomographs (CBCT) belonging to the UNESP ICT Radiology archive, were selected: 5 female and 5 male for each decade of life, beginning on twenties until there seventies, totalizing 30 female and 30 male. Three-dimensional models were generated for each exam and measurements were performed with three-dimensional angular measuring tools using OnDemand 3D software (Cybermed Inc., Tustin, CA, USA) on the MNA. The MNA was measured considering the posteriormost portion of the coronoid process, the lowest point of the mandibular notch, and the anteriormost point of the condylar process of the mandible. The MannWhitney test was performed with the intention of establishing the possible comparative relationships between the values of angular measurements and sex. Results: No statistically significant differences were found between mandibular incision measurements in both sexes, as well as when comparing the angular measurements of the mandibular incisions and the different age groups studied, when a Kruskall-Wallis test was performed. Conclusion: It was concluded that the structure being evaluated did not appear to be an instrument capable of contributing to forensic anthropology evaluations. (Au)

Objetivo: O objetivo deste estudo foi analisar o ângulo de abertura da incisura mandibular (AIM) como uma possível ferramenta para predição sexual e estimativa de idade, de modo a contribuir com estudos antropológicos forenses. Materiais e Métodos: Para tanto, foram selecionadas 60 tomografias computadorizadas de feixe cônico (TCFC) pertencentes ao arquivo de Radiologia das ICT/UNESP: 30 do sexo feminino e 30 do sexo masculino, contendo 5 exames para cada sexo na 2ª, 3ª, 4ª, 5ª, 6ª e 7ª décadas de vida. Foram gerados modelos tridimensionais para cada exame e as medições foram realizadas com ferramentas de medição angular tridimensionais usando o software OnDemand 3D (Cybermed Inc., Tustin, CA, EUA) nos AIMs. O AIM foi medido considerando a porção mais posterior do processo coronoide, o ponto mais baixo da incisura mandibular, e o ponto mais anterior do processo condilar da mandíbula. O teste de Mann-Whitney foi realizado com o intuito de estabelecer as possíveis relações comparativas entre os valores das medidas angulares e sexo, que não foram encontradas diferenças estatisticamente significantes entre as medidas de incisão mandibular em ambos os sexos, assim como quando comparamos as medidas angulares da incisões mandibulares e as diferentes faixas etárias estudadas, foi realizado o teste de Kruskall-Wallis. Resultados: Em relação à reprodutibilidade das medidas, verificou-se que houve reprodutibilidade entre as medidas repetidas. Conclusão: Concluiu-se que a estrutura avaliada não parece ser um instrumento capaz de contribuir para as avaliações antropológicas forenses. (AU)

Observation of sex chromatin in exhumed bones, evaluation of their diagnosis value / Observación de la cromatina sexual en osamentas exhumadas, evaluación de su valor diagnóstico

Observation of sexual chromatin has shown to be very helpful in gender forensic diagnosis. In the present study we analyzed the diagnosis performance of the method in, non-treated or treated with conventional bone techniques, exhumed bone pieces. We used long bones of male and female individuals, the method applied is described in Suazo et al. (2010). In the non-treated exhumed pieces, the general accuracy of the method was 75 percent, while in the treated pieces the method was inapplicable due to the lack of cells in the tissue. Our results suggest that it is possible to determine the sex of aged human bones buried under different conditions through a fast and simple histological method, but the treatment with physical and chemical means eliminates the remaining cells in the bone tissue.

La observación de la cromatina sexual ha demostrado ser útil en el diagnóstico forense del sexo. En este estudio analizamos el rendimiento diagnóstico del método en piezas óseas exhumadas no tratadas y tratadas mediante osteotécnica convencional. Utilizamos muestras de huesos largos de individuos de sexo masculino y femenino, el método se aplicó de acuerdo a lo descrito por Suazo et al., (2010). En las piezas exhumadas no tratadas la exactitud general del método fue del 75 por ciento, mientras que en las piezas tratadas el método resultó inaplicable, debido a la ausencia de células en el tejido. Nuestros resultados sugieren que es posible determinar el sexo en osamentas humanas exhumadas de larga data y en diferentes condiciones de enterramiento, mediante un método histológico rápido y sencillo, pero que el tratamiento por medios físicos y químicos elimina las células remanentes en el tejido óseo.

Sexual dimorphism in the foramen magnum dimensions / Dimorfismo sexual en las dimensiones del foramen magno

The purpose of this study is to assess the presence of sexual dimorphism in the foramen magnum size. We analyzed 211 human skulls from the collection of the Universidade Federal de Sao Paulo, with a record of sex and age determined using anteroposterior and transverse diameters of foramen magnum, and their differences by gender (p<0.05) were ascertained. Fischer linear discriminant function was calculated and the value for the classification of these variables was determined. All the dimensions were found to be higher, and in men's skulls, the foramen magnum size had low discriminating power and were accurately classified only in 66.5 percent skulls. Our results show that this quantitative indicator is of limited practical value and should be supplemented with qualitative indicators of sexual dimorphism in the occipital bone to improve the accuracy in the sex diagnosis.

El propósito de este estudio fue evaluar la presencia de dimorfismo sexual en las dimensiones del foramen magno. Se analizaron 211 cráneos humanos de la colección de la Universidade Federal de Sao Paulo, con registro de sexo y edad, se determinaron los diámetros anteroposterior y transverso máximo del foramen magno y se establecieron las diferencias por sexo (p<0,05), se determinaron las funciones lineales discriminantes de Fischer y se calculó la utilidad para la clasificación de estas variables. Todas las dimensiones resultaron mayores y significativas en cráneos de hombres, las dimensiones del foramen magno presentaron un bajo poder discriminante y clasificaron correctamente el 66,5 por ciento de los cráneos. Nuestros resultados muestran que este indicador cuantitativo es de limitada utilidad práctica y debe ser complementado con los indicadores cualitativos de dimorfismo sexual en el hueso occipital para mejorar la exactitud en el diagnóstico del sexo.

Evaluating accuracy and precisión in morphologic traits for sexual dimorphism in malnutrition human skull: a comparative study

One of the most important purposes of anthropological studies of human skeletons protocol is the determination of sex. Some skulls may be wrongly classified due to systemic conditions presented during the life of individuals who affected the muscle forces that act on bones, as is the case of severe malnutrition. The purpose of this study is to analyze the effect of severe malnutrition on morphological determinants of sexual dimorphism classically studied in the visual analysis of the skull. 163 human skulls were analized with sex, age and cause of death known, belonging to the collection of Universidad Federal de Sao Paulo (UNIFESP). We performed visual inspection of the skull and diagnosis of sex based on size and overall architecture of the skull, an aspect of the zygomatic bone, size and roughness of the mastoid process, ridges of the occipital bone and general appearance of the jaw. The skulls were classified into two groups according to whether severe malnutrition had described in his cause of death (n=60) or had other cause of death (n=103). The results of the inspection were compared with the registry to determine the accuracy in diagnosis and sensitivity of the method for male and female in both groups analyzed. In the group with malnutrition the best indicator was the appearance of the zygomatic bone, with a 86.6 percent accuracy. In another group closely was found in the size of the mastoid (87.3 percent). In both groups the highest values of sensitivity were for male (83.3-95.3 percent). The sensitivity to female showed lower values in the group without malnutrition (69.2-76.9 percent) than in the group with malnutrition (72.4-89.65 percent), these differences were statistically significant (p<0.05 ).

Uno de los propósitos más importantes del protocolo antropológico de estudios de osamentas humanas, es la determinación del sexo. Algunos cráneos pueden ser clasificados erróneamente debido a condiciones sistémicas presentadas durante la vida de individuos que hayan afectado a las fuerzas musculares que actúan sobre el hueso, como es el caso de la desnutrición severa. El propósito de este estudio fue determinar la exactitud y confiabilidad, sobre los parámetros morfológicos determinantes de dimorfismo sexual, clásicamente estudiados en el análisis visual del cráneo, para los dos grupos que componen la muestra, uno con desnutrición acompañando el momento del deceso y otro con causa de muerte sin ese factor acompañante. Se utilizaron 163 cráneos humanos de sexo, edad y causa de muerte conocido, pertenecientes a la colección de la UNIFESP. Se realizaron la inspección visual del cráneo y el diagnóstico de sexo en base a: tamaño y arquitectura general del cráneo, aspecto del hueso cigomático, tamaño y rugosidades del proceso mastoides, rugosidades del hueso occipital y aspecto general de la mandíbula. Los cráneos fueron clasificados en dos grupos, de acuerdo a si presentaron desnutrición severa descrita en su causa de muerte (n=60) o presentaban otra causa de muerte (n=103). Los resultados de la inspección se compararon con la del registro para determinar la exactitud en el diagnóstico y la sensibilidad del método para hombres y mujeres, en los dos grupos analizados. En el grupo con desnutrición, el mejor indicador resultó el aspecto del hueso cigomático, con un 86,6 por ciento de exactitud. En el otro grupo, la mayor exactitud se encontró en el tamaño del proceso mastoides (87,3 por ciento). En ambos grupos, los mayores valores de sensibilidad fueron para hombres (83,3-95,3 por ciento). La sensibilidad para mujeres presentó menores valores en el grupo sin desnutrición (69,2-76,9 por ciento) que en el grupo con desnutrición (72,4-89,65 por...

Blind test of mandibular morphology with sex indicator in subadult mandibles

Loth & Henneberg (2001) indicated that it was possible determine the sex with a high degree of accuracy (81 percent) in mandibles of children by observing the shape of the mandibular body. The purpose of this study was to evaluate in mandibles of Brazilians subadults the proposed method consistency; were used mandibles of 33 Brazilian children between 0 and 1 year of age, known sex, belonging to the collection of skulls of the Federal University Sao Paulo (UNIFESP). We performed a blind test in two sessions by one observer based on the parameters described by Loth & Henneberg. The results show between 57.5 and 60.5 percent of accuracy, being the most sensitive test for determining male (70 percent) than for females (38-46 percent). The results presented are lower than those reported by Loth & Henneberg and justify the need to assess the diagnostic methods of sex in subadults in specific populations.

Loth & Henneberg (2001) indicaron que era posible la determinación del sexo con un alto nivel de exactitud (81 por ciento) en mandíbulas de niños, mediante la observación de la forma del cuerpo mandibular. El propósito de este estudio fue evaluar en mandíbulas de subadultos brasileños, la consistencia del método propuesto. Para ello se utilizaron 33 mandíbulas de niños brasileños de entre 0 y 1 año de edad, de sexo conocido, pertenecientes a la colección de cráneos de la Universidade Federal de Sao Paulo (UNIFESP), Brasil. Se realizó un test ciego en dos sesiones por un sólo observador, en base al parámetro descrito por Loth & Henneberg. Los resultados obtenidos muestran entre un 57,5 y 60,5 por ciento de exactitud, siendo el test más sensible para la determinación del sexo masculino (70 por ciento), que para el sexo femenino (38-46 por ciento). Los resultados expuestos son inferiores a los reportados por Loth & Henneberg y justifican la necesidad de evaluar los métodos de diagnóstico de sexo en subadultos, en poblaciones específicas.

An Autopsy Case of a Transsexual Woman / 대한법의학회지

Transsexualism is a variety and complexity of conditions to the desire for sex change and may require medical treatments over psychological evaluations in some patients. Consequently, there is a potential confusion in the determination of anatomical sex in transsexuals arising from administration of hormone and/or sex reassignment surgery. In this article, we represent a case of a 52-year-old "woman"found dead on the road-side. "She"was naked on the scene and supposed to be murdered by strangulation of he neck. Surprisingly, autopsy findings as well as DNA typing revealed that "she"was transsexual once a man. We discuss medicolegal problems posed by medico-surgical treatment in transsexuals.

A Preliminary Anthropological Analyses of the Casualties from the Korean War during the Year 2000 -2001 Excavation / 체질인류학회지

In commemoration of the 50th anniversary since the Korean War, Korean government has initiated a four -year project beginning from the year 2000 to 2003 to excavate the remains of soldier casualties from the Korean War. During the year 2000 -2001 excavation total 555 casualties (minimum number of individual; MNI) are discovered around the southern parts of Korean peninsula. On the basis of the bone remains anthropological researches including the determination of sex, the estimation of age and stature have been carried out. All casualties are determined as male mainly based on the characteristic features of the innominate bone of the pelvis. Estimation of age is gained from 313 individuals. Over 64% of the casualties were estimated between the age 20 -24 years old and almost 20% were between the age 15 -19 years old. From these data, it has been conformed that the majority of soldiers can be classified as being in a young age category Total 270 individuals are examined for estimation of statures. Approximately 68% of the findings were estimated to have been between the height 160 -170 cm in proportion, and almost 14% of findings were below 160 cm tall. Identifying the remains of casualties are carried out by uncovered belongings, taking note of eyewitness accounts, and applying scientific methods. A total of 34 individual names were identified, and among them only four soldiers have been confirmed. 27 are still in the process of verification, and the rest are nearly impossible to identify.