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Objective To observe the effect of atorvastatin on mixed dyslipidemia in type 2 diabetic patients. Methods 39 patients of type 2 diabetic with mixed dyslipidemia were taken with atorvastatin for 6 months,and the change of total cholesterel(TC),triglyceride(TG),low-debsity-lipoprotein-cholesteral(LDL-C),high-debsity-lipopro- tein-cholesteral(HDL-C)were observed.The incidence of side-effect was recorded.Results TC,TG,LDL-C were obviously reduced and their extent of reduction were 26.17 %,54.97 %,38.92 %.HDL-C was obviously increased and it's extent of increase was 14.81%(P
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Objective To examine the serum high-sensitivity C-reactive protein(hs-CRP)levels in subjects with type 2 diabetic mellitus(DM)or DM accompanied by cerebral infarction(DM+CI),and the relationship be- tween the serum high-sensitivity C-reactive protein(hs-CRP)levels,and to investigate risk factors of cerebral infarc- tion in patients with type 2 diabetic mellitus.Methods The serum high-sensitivity C-reactive protein(hs-CRP)lev- els were measured in 50 DM patients,50 DM+CI patients and 30 healthy controls by ultra-sensitive immunoassay. hs-CRP values and its relationship with cerebral infarction in patients with type 2 diabetic mellitus and other factors, such as age,BMI,TG,etc,were analyzed.Results Univariate analysis revealed significant differences in hs-CRP concentrations between controls[(0.73?0.46)mg/L]and subjects with DM[(2.26?1.38)mg/L],or subjects with DM+CI[(3.82?2.67)mg/L](P
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0.05) during the experiment. The TC of middle dose GSPE group was marked ly different compared with that of normal group(P