RESUMO
Background: Artificial inseminations of donor semen (AID) involve use of heterologous donated semen for conception in infertile couple when indicated or in a single woman desirous of pregnancy. Its practice often requires regulation to address possible ethical and legal issues which may arise. In formulating acceptable guidelines/policies, the perspectives of health professionals and the participants should be considered. Therefore, we sought to explore the knowledge and perception of semen donation for artificial insemination among health professionals.Methods: A cross sectional study conducted on consenting health workers in a single health institution using a structured questionnaire to assess their knowledge and perception on artificial insemination of donor semen (AID). Descriptive and analytical statistics were applied to the data collected with a statistically significant value of <0.05.Results: One hundred and twenty-one health professionals completed the questionnaires. The mean age of the respondents was 27.58±5.5years. Sixty of the respondents were males while 61 were females. Eighty-four of the respondents (69.4%) demonstrated good knowledge of AID while 37 (30.6%) had poor knowledge. Cadre of health professionals and marital status influenced the knowledge of respondents. Perceptions on AID varied among the respondents mostly influenced by psycho-social factors and possible legal disputes on third party reproductive process. None of the male respondents has ever donated semen and willingness to donate semen was low; with anonymity preferred by the willing donors.Conclusions: Substantial knowledge gap of AIDS existed among health professionals which were influenced by cadre and marital status. Psycho-social factors and possible legal disputes influenced their perceptions of AID.
RESUMO
Through the analysis of the selected case discussion, put forward the current often encountered in clinical practice for pure artificial insemination about some ethical problems in the implementation process of tech-nology, current situation and aims at the discussion the reproductive committee is carried out in the guidelines for the essence of artificial insemination technology functions:to provide correlation ethics consultation to demanders, 2 it is to assisted reproductive technology, and the correlation research to carry out the supervision and guidance.
RESUMO
Objetivo: determinar la incidencia y el riesgo de preeclampsia en pacientes infértiles a las que se les realizó inseminación con semen de donante o de su pareja. Materiales y métodos: cohortes históricas de pacientes a las cuales se les realizó inseminación intrauterina (IIU) homóloga o heteróloga y que lograron embarazo mayor de 20 semanas de gestación, entre enero del 2000 al 31 de diciembre del 2009 en el Centro de Biomedicina Reproductiva del Valle - Fecundar. Se excluyeron pacientes con trastornos endocrinos y metabólicos (Diabetes Mellitus, enfermedades del colágeno) o enfermedades crónicas (hipertensión arterial, trombofilias). El tamaño de la muestra fue de 155 pacientes expuestas a inseminación heteróloga y 310 a inseminación homóloga. Se evaluó la presencia preeclampsia y el resultado perinatal, así como el tipo de inseminación, edad, raza, nivel educativo, índice de masa corporal (IMC en kg/m²), indicación de la inseminación, número de ciclos previos y estrato socioeconómico. Se estimó la incidencia acumulada y se compararon las dos cohortes por medio del RR con su respectivo intervalo de confianza. Se estratificó por edad. Resultados: 428 mujeres cumplieron los criterios de selección. La incidencia de preeclampsia se presentó en un 6% (24/428), un 4% (11/264) en las IIU homólogas y 7,93% (13/164) de las IIU heterólogas. Se encontró que no hay diferencias en el riesgo de preeclampsia de acuerdo con el tipo de inseminación y al ajustar por edad RR: 1.18 (IC 95%: 0,54-2,58). Conclusiones: en la IIU heteróloga se encontró una incidencia mayor de preeclampsia. Sin embargo, no hay asociación con el desarrollo de preeclampsia.
Objective: Determining preeclampsia incidence and risk in infertile patients who have been inseminated with semen from a donor or from their partner. Materials and methods: This study dealt with historical cohorts of patients who had been subjected to homologous or heterologous intrauterine insemination in the Fecundar infertility centre and who had managed to become pregnant for more than 20 weeks gestation between January 2000 and 31st December 2009. Patients suffering endocrine and metabolic disorders (diabetes mellitus, collagen diseases) or chronic diseases (arterial hypertension, thrombophilia) were excluded. Sample size was 155 patients regarding heterologous insemination and 310 for homologous insemination.The presence of preeclampsia and perinatal result were evaluated and type of insemination, age, ethnicity, educational level, body mass index (BMI in Kg/m²), indication of insemination, number of prior cycles and socioeconomic strata were also measured. Accumulated incidence was estimated and two cohorts were compared by RR with respective confidence intervals. Females were stratified by age. Results: 428 females fulfilled the selection criteria. There was 6% (24/428) preeclampsia incidence, 4% (11/264) homologous IUI and 7.93% (13/164) heterologous IUI. No differences were found regarding the risk of preeclampsia according to the type of insemination and after being adjusted for age (1.18 RR; 0.54-2.58 95%CI). Conclusions: Greater preeclampsia incidence was found in heterologous IUI; however, there was no association with the development of preeclampsia.