Efficacy of flash heat treatment vs holder pasteurization on antimicrobial activity and immunoglobulin: A preservation in donor breast milk

@#<p style="text-align: justify;"><strong>BACKGROUND:</strong> Human milk is considered the optimal nutritional source for infants. Due to the possibility of microbial contamination during collection and handling, milk is pasteurized to prevent transmission of pathogens. In low-income areas where pasteurization is inaccessible, the pursuit for the best alternative in rendering donor milk safe remains.</p><p style="text-align: justify;"><strong>OBJECTIVE:</strong> We aimed to determine and compare the efficacy of flash heat treatment and holder pasteurization in preserving human milk IgA while reducing bacterial contamination of donor breast milk.</p><p style="text-align: justify;"><strong>METHODOLOGY:</strong> This is an experimental study which utilized pooled donor breastmilk from healthy mothers later subjected to bacterial analysis and immunoglobulin A level determination prior to and post flash heat treatment and pasteurization. Standardized scores were used to normalize population with unknown parameters. T-test comparison of means and Levene's test for equality of variances were used.</p><p style="text-align: justify;"><strong>RESULTS</strong>: Twenty samples of aliquoted breastmilk were subjected to pasteurization and flash heat treatment, both yielding a statistically significant reduction in colony-forming units using Blood agar and MacConkey plates. These sample groups also underwent IgA level determination using Bindarid Kit IgATM and there was no significant decline in IgA levels.</p><p style="text-align: justify;"><strong>CONCLUSIONS:</strong> Flash heat treatment may be an alternative for holder pasteurization in providing safe and effective breastmilk.</p>

The effects of expressed maternal milk and donor breast milk for feeding preterm infants / 国际儿科学杂志

When directly breast feeding for preterm infants is not available,a preferred alternative is expressed maternal milk or donor breast milk.The evidences to date indicated that feeding preterm infants with expressed maternal milk and donor breast milk was associated with a slower growth in the early postnatal period,the effects on long-term growth in preterm infants was still unclear.Feeding with expressed maternal milk and donor breast milk could deliver preterm infants a degree of specific components of human milk.The potential benefits of the specific components for preterm infants were associated with promoting neurodevelopment and decreasing the incidence of feeding complications.Before expressed maternal milk and donor breast milk are widely used in clinical practice,further studies are still needed to explore the long-term effects on growth and development in preterm infants.