RESUMO
OBJECTIVE:To discuss the characteristics and regularity of drug-induced deaths so as to promote the ra?tional use of drugs in the clinic.METHODS:The case reports on drug-induced deaths retrieved from Chinese medical science periodicals from1998to2004collected in CHKD periodicals knowledge base in China hospital digital library were analyzed statistically.RESULTS:Of the total drug-induced deaths,43.85%were by iv,which dominate the first place in terms of fatality rates;antimicrobials,Chinese herbal medicine,antineoplastic agent and drugs that affect blood system and hematopoietic system dominated the first5places in terms of the fatality rates;the mortality of allergic shock was higher,which made up about31.81%.CONCLUSION:An indispensable measure to reduce drug-induced disease and its fatality rate is to strictly control the indications of medication and enhance the cultivation of professional staffs'professional activities and service quali?ty.
RESUMO
OBJECTIVE:To investigate the characteristics and the prevention of traditional Chinese medicine-induced death. METHODS: The traditional Chinese medicine-induced death cases from 1994 to 2006 collected by retrieving full-text data base of CHKD were analyzed statistically. RESULTS: Of the total traditional Chinese medicine-induced death cases, drugs were chiefly administered by intravenous drip and oral administration, and allergic shock was the chief death causes. CONCLUSION: Clinicians and pharmacists should attach great importance on the ADRs induced by traditional Chinese medicines to ensure safe and effective drug use.