Effects of Sagacious Confucius' Pillow Elixir on cognitive function in type 2 diabetic rats / 中国中药杂志

Type 2 diabetes mellitus (T2DM) is the leading threat to human health in China, and severe cognitive impairment often occurs in most T2DM patients. Although Sagacious Confucius' Pillow Elixir is a type of classical traditional Chinese medicine for cognitive impairment in clinic, the mechanism has not yet been completely defined. In this study, an experimental model of type 2 diabetes mellitus (T2DM) was established by injecting Sprague Dawley (SD) rats with streptozocin (STZ), so as to compare the learning and memory ability, hippocampal neurons pathological changes, beta amyloid protein (A beta) content, degree of Tau protein phosphorylation, blood glucose and insulin level. The results showed that the Sagacious Confucius' Pillow Elixir could improve the learning and memory ability of STZ injected rats, reduce the level of A beta content both in hippocampus and serum, effectively reduce Tau protein phosphorylation degree, and also significantly alleviate hippocampal pathological injury, blood glucose, insulin and other basic indicators. The results showed that Sagacious Confucius' Pillow Elixir can alleviate the hippocampal pathological damage caused by STZ, and is expected to provide a theoretical basis for human T2DM patients in clinical adjuvant therapy.

Y también la vejez tiene su historia / The old age has its history too

Desde el principio de los tiempos, la humanidad ha crecido, en términos generales, en distintas etapas: Infancia, Niñez, Adolescencia, Juventud, Edad adulta y Senectud.Lo interesante es que la longevidad, se ha convertido en nuestro siglo, en el destino de la mayoría, al menos en los países desarrollados. Vivir viejo está bien, pero lo importante es vivir plenamente disfrutando de esa etapa.El trabajo es una mirada histórica desde la lejana antigüedad hasta el presente, analizando los criterios en diferentes culturas, referidos a la magnífica legión de los viejos en aumento progresivo

Since time began mankind has grown, in general terms, in different stages: Infancy; Childhood, Adolescence, Youth, Adulthood and Old Age.The interesting point is that, in our century, longevity has become most people’s fate, at least in developed countries. Living old is good, but the important issue is living wholly, enjoying this stage. This work is a historical outlook from the ancient times up to the present, analyzing criteria in different cultures which refer to the marvelous and continuously increasing legion of the old

Bioavailability of elixir theophylline (siriraj formula) in Thai asthmatic children.

The bioavailability of Elixir Theophylline (Siriraj Hospital Formula) and Table Aminophylline (The Government Pharmaceutical Association) was compared with Elixir Quibron in Thai asthmatic children. The mean rate of absorption and the extent of drug absorption were not significantly different for local made drugs, compared with that of an imported one. With regards to the mean maximum serum levels (Cmax) and time to maximum serum level (Tmax) values, there were also no significant differences between two local preparations and an innovative one. Thus, the results suggest that the local made theophylline drugs possess the same efficacy as the imported drug.