Research on the Ethical Supervision of Human Gene Editing Technology: Based on the Perspective of Game Theory / 中国医学伦理学

In view of the current norms and demands of human gene editing technology at home and abroad, the paper explained that the regulatory difficulties faced by human gene editing technology were due to the conflict between economic interests and moral bottom line by constructing a game model in a hypothetical way. On this basis, the ideas of the supervision mode of human gene editing technology were put forward: establish unified international standards based on the country as the main body, enact more stringent and effective laws, to jointly deal with the behavior of genetic manipulation of human gametes, zygotes and embryos for the purpose of reproductive, and ensure the normalization and legalization of gene editing technology to avoid technology abuse.

Research on Ethical Supervision of Emerging Body Enhancement Technique / 中国医学伦理学

The emerging body enhancement technique repairs the "defective structure" of the body from the inside of the person, so that the body can get the support of technical strength. The emerging body enhancement technique starts the process of gradual disintegration of natural body, and its technical oppression dispels individual freedom, and forms a deep connection between power and capital in emerging body enhancement technique. In order to promote the synthetic development between the technique progress and the order construction, it is significant to rescue the emerging body enhancement technique from the fighting between the biological conservatism and the super humanism, promote the development of the emerging body enhancement technique from the professional education to the popularity education, regulate the development of the emerging body enhancement technique with the theory framework of the body ethics, and promote the development of the supervision of the emerging body enhancement technique to all directions and the whole process.

Ethical Enlightenment of Foreign Rare Disease Treatment Guarantee System to China / 中国医学伦理学

By summarizing the policies and regulations of foreign countries on rare disease research and drug research and development, referring to the relevant policy support of treatment guarantee system in the development of rare diseases abroad, and combining with China’s national conditions, this paper analyzed the feasible points that China can learn from, and then put forward some suggestions on the ethical problems existing in the current rare disease research, so as to provide reference suggestions for the relevant policy formulation of rare disease treatment guarantee in China: adjusting regional differences based on the principle of fairness, and establishing a national rare disease information collection center; improving the ethical quality of scientific research in pharmaceutical companies, and strengthening ethical supervision; and the government and society fulfill their obligations to protect the rights and interests of patients with rare diseases.

Standardization of Ethical Continuing Review for the Improvement of Ethical Supervision of Clinical Researches / 中国医学伦理学

This paper introduced from the aspects of the importance of ethical continuing review, the type and characteristics of the review, the recommendations for strengthening the ethical continuing review, and continuing review as an important means of ethical supervision and so on. It is recommended that it should effectively improve the efficiency of six ethical continuing reviews including the revised plan, annual or regular tracking, serious adverse events, non-compliance/violation program, suspension/early termination and conclusion through the construction of an ethical informationization platform, the reinforcement of researcher training and education,the communication with researchers and their teams, and carry out efficient ethical supervision of various stages of research projects during and after their completion. Only doing continuing review can put the subject protection into practice.

Discussion on Ethical Supervision and Informed Consent of Biobank / 中国医学伦理学

With the constant deepening of medical research and the need of translational medicine,it is neces-sary to normalize the construction of biobank with high - standard. However,there are no issued ethical guideline and standard for biobank in China at present. Based on this,this paper expounded the related ethical guidelines for biological samples and the review and supervision of ethics committee,and deeply expounded the issues of informed consent related to biobank,that is,the informed information of informed consent,the need to get explicit consent from the donor when collect,preserve and use the biological samples and the mode of informed consent,in order to lay the foundation for the future development of standards and norms.