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Objective To explore developmental states on the preterm and term neonatal brain white matter based on the co-variation of metrics derived from diffusion tensor imaging(DTI).Methods This work enrolled 66 neonates,consisting of 33 preterm(21 males and 12 females;gestational age:30.143-36.286 weeks)and 33 full-term neonates(22 males and 11 females;gestational age:37.000 -41.429 weeks).DTI derived metrics included axial diffusivity(AD),radial diffusivity(RD),and fractional anisotropy(FA).Spearman's rank correlation between metrics and postmenstrual age was analyzed in the preterm and term neonates.Developmental states were evaluated according to the method proposed by Dubois:fiber organization was associated with increased AD, decreased RD and increased FA;pre-myelination was related to decreased AD,decreased RD and unchanged/increased FA;myelination was revealed by unchanged AD,decreased RD and increased FA.Mann-Whitney U test was used to compare DTI metrics between the preterm and term neonates.Results According to the method proposed by Dubois,posterior limb of internal capsule and corpus callosum underwent myelination in the preterm-neonate period.Cerebral peduncle started myelination in the term-neonate period.Superior corona radiate,inferior fronto-occipital fasciculus and external capsule underwent pre-myelination on preterm and term neonates.FA values were higher in term neonates than those in preterm neonates in all the selected regions(P＜0.05).AD and RD values were lower in term neonates than those in preterm neonates in the selected regions except for cerebral peduncle(P＜0.05).Conclusion Changes in DTI metrics and the method of Dubois can be used to quantitatively evaluate developmental states of the neonatal brain white matter.The changes coincided with DTI variations associated with pre-myelination and myelination.White matter development is delayed in preterm neonates compared with term neonates.
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Introdução: Por causa do envelhecimento, o ser humano compromete algumas estruturas fisiológicas importantes para o desempenho da marcha Vale salientar que as modificações da marcha no idoso se processam em relação a fatores tanto fisiológicos como emocionais, interferindo no estilo de vida que o idoso apresenta. Objetivos: Investigar o efeito de um programa de atividades psicomotoras na marcha e no bem estar físico, mental e social dos idosos. Metodologia: Trata-se de um estudo de intervenção sem grupo controle, descritiva, com abordagem quanti-qualitativa realizada na Clínica-Escola da Universidade Federal da Paraíba, João Pessoa-PB. A população do estudo foi constituída por 15 idosos. Para a coleta de dados, utilizou-se um instrumento com dados sociodemográficos, dados clínicos, exame físico, Mini Exame de Estado Mental, e avaliação de desempenho funcional da marcha (POMA-BRASIL). Estas avaliações faziam parte da triagem dos participantes, sendo o MEEM e o POMA realizados em três momentos da pesquisa, a cada dois meses. O estudo foi realizado no período de agosto a dezembro de 2011. No que se refere às considerações éticas, o estudo esteve de acordo com as normas da resolução 196/96. Quanto ao procedimento de intervenção, foram realizadas atividades psicomotoras cuja finalidade foi promover um fortalecimento muscular a partir dos elementos psicomotores, favorecendo um melhor desempenho da marcha, sendo desenvolvidas na água e no solo. Após o término do programa psicomotor, foram identificadas as percepções dos idosos através da técnica de entrevista individual, cuja pergunta norteadora foi: Qual a percepção acerca dos efeitos do programa psicomotor na sua vida? . Os depoimentos foram gravados, o que contribuiu para que as falas fossem transcritas com maior exatidão e fidedignidade. Para a análise dos dados quantitativos, utilizou-se a estatística descritiva e o teste de Friedman; sob o ponto de vista qualitativo, a análise de conteúdo de Bardin.
Introduction: Because of aging, the human undertakes some physiological structures important for gait performance is noteworthy that the changes of gait in the elderly are processed in relation to factors both physiological and emotional, interfering with the lifestyle that the elderly presents. Objective: to investigate the effect of a program of psychomotor activities in gait and physical well-being, mental and social of elderly,. Methodology: It is an intervention study, without group control, descriptive, with quantitative-qualitative approach, conducted in a Clinical School of the Federal University of Paraíba, João performance of gait (POMA-BRAZIL). These evaluations were part of the triage of participants, being PEEM and POMA, Pessoa-PB. The population of the study was composed by 15 elderly. For data collection was utilized an instrument with socio demographic data, clinical data and physical examination, the mini mental state examination and the evaluation of functional performed in three moments of the research, every two months. The study was conducted in the period from August to December 2011. Referring to ethical considerations, the study was in accordance to the rules of Resolution1196/96. Regarding the intervention procedure were carried out psychomotor activities whose purpose a muscle strengthening from the psychomotor elements, favoring a better gait performance, being developed in the water and soil. After finishing the psychomotor program were identified perceptions of elderly through the individual interview technique of which guiding question was: What is the perception about the effects of the psychomotor program in your life? Their statements were recorded, which contributed so that the speeches could be transcribed with higher accuracy and reliability. For quantitative data analysis was utilized descriptive statistics and Friedman s test, from the qualitative point of view, the content analysis of Bardin.