RESUMO
Thermal conditions are an important environmental factor in maintaining healthy pigs because they affect feed intake, growth efficiency, reproduction and immune responses in pigs. RAVI, a regenerative far-infrared heating system, can effect pig production by emitting an optimal far-infrared wavelength. Far-infrared radiation has been reported to increase microvascular dilation and vascular flow volume. The purpose of this study was to evaluate the immunobiological differences between pigs raised with the RAVI system and the gasoline heater system. Twenty-six-week-old weaned pigs were raised in two rooms that were equipped with a RAVI system or a gasoline heater for 8 weeks. A porcine atrophic rhinitis vaccine was administered after two weeks and transcriptome analysis in whole blood were analyzed at 2-week intervals. Signaling pathway analyses of the RAVI group at 8 weeks showed the activation of pathways related to nitric oxide (NO) production. This suggests that the application of RAVI might induce the production of NO and iNOS, which are important for increasing the immune activity. Similar to the result of microarray, phenotypic changes were also observed at a later period of the experiment. The increase in body weight in the RAVI group was significantly higher than the gasoline heater group at 8 weeks. The antibody titer against the vaccine in the RAVI group was also higher than that the gasoline heater group at 4 weeks and 8 weeks. This evaluation of the use of a far-infrared heating system with pigs will be helpful for applications in the pig farm industry and pig welfare.
Assuntos
Agricultura , Peso Corporal , Gasolina , Perfilação da Expressão Gênica , Calefação , Temperatura Alta , Óxido Nítrico , Reprodução , Rinite Atrófica , SuínosRESUMO
Objective • To explore therapeutic effects of far-infrared radiation (FIR) therapy on chronic lower extremity lymphedema accompanied with dermatolymphangioadenitis (DLA), occurring after gynecological tumor resection. Methods • The enrolled patients received regular sessions using the FIR therapy machine over the 20-day treatment course (five days in each week). Clinical and laboratory outcome measures were carried out before and after treatment. Clinical outcome measures included DLA seizure frequency, patients' subjective feedback, quality of life, and side effects. Laboratory outcome measures included bacterial cultures and concentrations of in.ammatory cytokines, detected in serum and local lymphedema tissue.uid samples. Results • A total of 64 cases completed FIR treatment and clinical curative effect evaluation, including 11 cases at the same time completing the laboratory tests. The frequency of DLA decreased during treatment (P=0.000). The ef.ciency rate was more than 50% for 63 (98%) patients receiving treatment. Even 50 patients (78%) did not experience a single episode of DLA recurrence in the whole year after treatment. Patients reported a subjective decrease in lymphedema-related symptoms (all P<0.05), including tightness, heaviness, pain, hardness, soreness, discomfort, heat, fullness, weakness, and numbness. Patients' quality of life was improved after treatment (P=0.000). Laboratory analysis showed an elevation in serum concentration of IL-1β after FIR therapy (P<0.05) and reduction in local tissue.uid concentrations of IL-2, IL-10 and IL-18 (all P<0.05). Bacterial culture results were both negative before and after treatment. Conclusion • FIR therapy provides an effective treatment modality for patients with chronic lymphedema accompanied with DLA that develops secondarily from the treatment of gynecological malignancies, whose therapeutic effects may be due to reduce immune dysfunction within local lymphedema tissues.
RESUMO
Objective To investigate the effect and psychological intervention of the treatment of hemodialysis internal fistula with Hirudoid combined with far infrared ray. Methods 80 cases of hemodialysis fistula were diagnosed and treated from January 2014 to December 2016 in Lishui Central Hospital,according to different treatment intervention methods, which were divided into two groups, each group with 40 cases. The control group was treated with routine nursing and far infrared therapy, and the observation group was treated withpsychological intervention and Hirudoid+far infrared therapy. The clinical efficacy, the improvement of clinical symptoms and the incidence of complications were compared between the 2 groups. Results The clinical effect of the observation group was better than that of the control group, the improvement of the clinical symptoms was better than that of the control group,the complication rate was lower than the control group,the difference was statistically significant (P<0.05). Conclusion The clinical effect of psychological intervention plus Hirudoid+far infrared ray in the treatment of hemodialysis fistula patients is significant,which can effectively improve the clinical symptoms and complications in patients with less, and is worthy of clinical application.