Técnica híbrida (TH) versus estándar (TS) en la punción con aguja fina guiada por ecoendoscopia para lesiones sólidas del páncreas / Hybrid technique versus standard technique for endoscopic ultrasound guided fine needle aspiration of solid pancreatic lesions

Resumen La ultrasonografía endoscópica (USE) se usa ampliamente para evaluar enfermedades pancreatobiliares, especialmente masas pancreáticas. La USE tiene una buena capacidad para detectar masas pancreáticas, pero no es suficiente para el diagnóstico diferencial de varios tipos de lesiones. La aspiración endoscópica con aguja fina guiada por ultrasonido (USE-PAF) es el método de diagnóstico de elección para masas pancreáticas y su precisión se afecta por diversos métodos de punción. Materiales y métodos: nuestro objetivo fue evaluar el rendimiento diagnóstico de la técnica de succión estándar (TS) versus la técnica húmeda híbrida (TH) en el estudio de lesiones sólidas en páncreas, utilizando un diseño prospectivo, con ocultación única, aleatorizado y controlado, que incluye a pacientes con diagnóstico de lesión sólida en páncreas a los que se realizó USE-PAF desde mayo de 2014 a junio de 2016. Resultados: en total incluimos 65 pacientes, 34 (52,3%) se asignaron a USE-PAF con TH y 31 (47,7%) pacientes a USE-PAF con TS. Se encontró que la frecuencia relativa porcentual respecto a la técnica de punción en la USE-PAF en lesiones sólidas de páncreas, que permite obtener la cantidad de tejido adecuado para el diagnóstico citológico, fue de 85,2% para la TH y 71% para la TS, con un OR de 2,35 (IC 95%; 1,2-4,7) a favor de la TH. Conclusión: este estudio sugiere que la TH es superior a la TS en el diagnóstico de las lesiones sólidas del páncreas, por lo cual, dado que la implementación de esta técnica no aumenta costos y es muy sencilla, sugerimos que sea la técnica de elección cuando se necesita puncionar una lesión sólida.

Abstract Endoscopic ultrasound (EUS) is widely used to evaluate pancreatobiliary diseases, especially pancreatic masses. EUS has a good ability to detect pancreatic masses, but it is not sufficient for differential diagnoses of various types of lesions. Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) is the diagnostic method of choice for pancreatic masses, but its accuracy is affected by various puncture methods. Materials and methods: Our objective was to compare the diagnostic yield of examinations of solid lesions in the pancreas by the standard suction technique (ST) with the yield of the hybrid technique (HT) using a prospective, single blind, randomized, controlled design. Patients diagnosed with solid pancreatic lesions who underwent EUS-FNA from May 2014 to June 2016 were included. Results: We included 65 patients, 34 of whom (52.3%) were assigned to EUS-FNA with HT, and 31 of whom (47.7%) were assigned to EUS-FNA with TS. We found that the relative frequency that HT successfully obtained an adequate amount of tissue for the cytological diagnosis was 85.2% while ST's relative frequency of success was 71%. The odds ratio was 2.35 (95% CI; 1.2-4.7) in favor of HT. Conclusion: This study suggests that the TH is superior to ST for diagnosis of solid pancreatic lesions. Since implementation of this technique does not increase costs and is very simple, we suggest that it become the technique of choice for EUS-FNA.

UNTRASONOGRAPHICALLY GUIDED FINE NEEDLE PUNCTURE ABSORBING CYTOLOGY EXAMINATION IN THE DIAGNOSIS OF CERVICAL LYMPH NODE TUBERCULOSIS / 现代医院

Objective To explore the clinical value of untrasonographically guided fine needle puncture ab -sorbing cytology examination in the diagnosis of cervical lymph node tuberculosis .Methods In March 2013 to June 2015 454 cases of suspected cervical lymph node tuberculosis cases were selected , and 454 suspected cases according to the voluntary principle were divided into two groups : US -FNAC groups: 326 cases with US -FNAC detection;FNAC groups: 128 cases, using FNAC.Statistical degree of two groups of detection sensitivity , specific, positive predictive value, negative predictive value and accuracy , and follow -up of two groups of complications .Results In US -FNAC group 326 cases, after the US -FNAC tested positie 308 cases, 304 cases confirmed by pathology after true positive and false positive 4 cases, through US -FNAC tested negatie 18 cases, were confirmed by pathology af -ter true negative, 15 cases of false negative in 3 cases; FNAC in the group of 128 cases of FNAC tested positie 107 cases, 102 cases confirmed by pathology after true positive and false positive in 5 cases, by FNAC tested negatie 21 cases, 12 cases confirmed by pathology after really negative , 9 cases of false negative.US -FNAC, the sensitivity of the detection of cervical lymph node tuberculosis (99.02%) than FNAC (91.89%), the difference was statisti-cally significant (p 0.05); US -FNAC, the accuracy of the detection of cervical lymph node tuberculosis (95.30%) than FNAC (89.47%), the difference was statistically significant (p <0.05); US - FNAC, incidence of complications (1.23%) is lower than the FNAC group (4.69%), and the difference was statistically significant (chi -square =5.1095, p =5.1095,p <0.05). Conclusion US -FNAC is used for the diagnosis of cervical lymph node tuberculosis , and has the advantages of high sensitivity, high accuracy.So US -FNAC diagnosis in cervical lymph node tuberculosis suspected cases has the important clinical value.

Diagnóstico citológico de lesiones focales intra-abdominales en pacientes que acuden al Servicio de Gastroenterología del Hospital Central Universitario “Antonio María Pineda”: Barquisimeto-Estado Lara / Cytological diagnosis of intra-abdominal focal lesions in patients attending the Hospital Central Universitario

Las lesiones focales de los órganos intra - abdominales comprenden un amplio espectro, produciendo desde pocas o inaparentes consecuencias, hasta un deterioro significativo de la calidad de vida pudiendo representar una condición severa asociada con mal pronóstico y alta mortalidad. Determinar el diagnóstico citológico de lesiones focales intra-abdominales mediante punción aspiración con aguja fina en pacientes que acuden al Servicio de Gastroenterología del Hospital Central Universitario “Antonio María Pineda”. Barquisimeto. Estado Lara. Se realizó una investigación de tipo descriptiva transversal, practicándose punción aspiración con aguja fina a todos los pacientes con lesiones focales intra-abdominales que acudierón al Servicio de Gastroenterología del HCUAMP durante el periodo Julio 2008 - Diciembre 2008 excluyéndose aquellos con ausencia de un trayecto seguro para la aguja, poca abordabilidad de la lesión, trastornos de coagulación o trombocitopenia severa, infecciones de la piel en el área de la punción, enfermedades neurológicas agudas, estado crítico o terminal y pacientes poco colaboradores. 62% de los pacientes con lesiones focales intra-abdominales pertenecían al sexo femenino y 38% al sexo masculino. 54% de los pacientes tenían entre 40 y 69 años. La localización intra-abdominal más frecuente de las lesiones fue Hígado en 84%, Páncreas en 10% Retroperitoneo en 4% y Bazo en 2%. La categoría citológica fue benigna en 30% seguido de 23% maligna y 7% sospechosa para malignidad mientras que en 37% no se reportaron hallazgos citológicos patológicos. El diagnóstico citológico más frecuente de las lesiones benignas fue Absceso en 65%. De los pacientes con lesiones categorizadas como malignas, 62% presentó diagnóstico citológico de Adenocarcinoma, 15% Carcinoma, 15% neoplasia epitelial neuroendocrina y 8% Linfoma. No se presentaron complicaciones. La principal limitación fue la no disponibilidad de patólogo en el momento de la toma de las muestra...

Focal lesions in intra-abdominal organs comprehend a wide spectrum, resulting into a few or non-apparent consequences up to a significant damage of living standards, which might represent a severe condition associated with a bad patient outlook and high morbidity. Determining the cytological diagnosis of intraabdominal focal lesions by puncture/aspiration with fine needle in patients attending the Hospital Central Universitario Antonio Maria Pineda’s (HCUAMP) Gastroenterology Service, at Barquisimeto, State of Lara. A cross-sectioned descriptive research was developed; fine-needle puncture/aspiration was practiced on all patients with intra-abdominal focal lesions who attended the HCUAMP’s Gastroenterology Service between July-September 2008, excluding those who did not show a safe routing for the needle, scarce approachability to the lesion, coagulation disturbances, severe thrombocytopenia, skin infection on the puncture area, acute neurologic diseases, critical or terminal stage, and uncooperative patients. 62% of patients with intra-abdominal focal lesions were female, and 38% were male. 54% of patients were between 40 and 69 years old. The most frequent intra-abdominal lesions were: Liver, 84%; Pancreas, 10%; retroperitoneum, 4%; and Spleen, 2%. Cytological category was 30% benign, followed by 23% malignant; and 7% probably malignant, while 37% did not report pathologic cytological findings. The most frequent cytological diagnosis in benign lesions was 65% of abscess. From the patients with lesions categorized as malignant, 62% presented a cytological diagnosis of adenocarcinoma; 15%, Carcinoma; 15%, neuroendocrinal epithelial neoplasm; and 8% Lymphoma. No complications were present. The non availability of pathologist at the time of sample collection was the main limitation. The puncture/aspiration by ultrasound-guided fine needle in intraabdominal focal lesions is a rapid and efficient diagnosis alternative, rendering high specificity...