Fuzzy Cluster Analysis of Compositae Involved in Effective Patent of TCM Extract Combination on Drug Properties / 中国药房

OBJECTIVE:To classify the drug properties of Compositae involved in effective patent of TCM extract combina-tion. METHODS:Property,flavor and the meridian tropism of TCM were used as the parameters;by computer analysis software, fuzzy cluster analysis was conducted from Compositae mostly involved in effective patent of TCM extract combination which ap-proved before Jan. 1st in 2015 and kept till May 30th in 2015. RESULTS & CONCLUSIONS:27 ingredients of Compositae were involved with the functions as protecting liver almost. They were classified into 5 categories. The first category included 10 ingredi-ents as Dendranthema morifolium which were cold,bitter to taste,and in the liver and lung meridian,and all of them contained flavonoids compounds;the second category included 3 ingredients as Gnaphalium affine of which flavonoids compounds were main medicinal components;the third category included 5 ingredients as Atractylodes lancea which could protect liver and contained vola-tile oil;the forth category included 4 ingredients as Tussilago farfara which showed anti-inflammatory and anti-tumor effect;the fifth category included 5 ingredients as Erigeron breviscapus which contained ingredients for cardiovascular disease. Those catego-ries were similar not only in property,flavor and the meridian tropism,but also in active ingredients and effects. The researchers should further research TCM of which pharmacologic action are not well understood,by means of make reference to known TCM in the same category,and make preparation to save time and enlarge medicinal resource.

Biotipo morfológico facial en tres grupos étnicos colombianos: una nueva clasificación por medio del índice facial / Facial biotype in three Colombian ethnic groups: a new classification by facial index

El objetivo de este estudio es evaluar el índice facial de tres poblaciones colombianas y proponer un nuevo método para identificar los biotipos morfológicos faciales teniendo en cuenta el tipo de ascendencia. Para esto, se tomaron las medidas de Nasion a Gnation y la distancia Bicigomática con un calibrador digital en tres grupos étnicos diferentes: 63 niños de la población Ticuna (Amazonas), 68 niños del municipio de Puerto Tejada (Cauca) y 65 niños del municipio de Santiago de Cali (Valle). Por medio de la prueba post hoc T2 de Tamhane se determinó que las poblaciones son distintas y que el índice morfológico facial tradicional no discriminaba esas diferencias. Por tal razón se utilizó el método estadístico de conglomerados difusos con el fin de determinar el número de grupos o biotipos para cada tipo de ascendencia. Se concluyó, que las poblaciones mestizas y afro-descendientes tienen similitudes por lo cual se agruparon juntas y el algoritmo c-medias generó cuatro biotipos característicos, mientras que para la población indígena Ticuna (Amazonas) solo se generaron tres biotipos.

The aim of this study is evaluate the facial index of three Colombian populations and propose a new method to identifythe facial morphological biotypes taking into account the type of ascendancy. For this, measures were taken of Nasion to Gnation and bizygomatic distance with a digital caliper in three ethnic groups: 63 children from Ticuna population (Amazonas), 68 children from municipality of Puerto Tejada (Cauca) and 65 children from municipality Santiago de Cali (Valle). Through the post hoc Tamhane's T2 was determined that the populations are different and the facial morphological index did not discriminate these differences. We used the statistical method of fuzzy clusters to determine the number of groups or biotypes for each type of ascendancy. We concluded that mixed populations and African descent have similarities, therefore they were grouped together and the c-means algorithm generated four biotypes characteristic, while the indigenous population Ticuna (Amazon) only generated three biotypes.

Fingerprint of Pogostemon cablin by pyrolysis-gas chromatography and its fuzzy cluster analysis / 中草药

Object To study comparatively the fingerprint of Pogostemon cablin (Blanco) Benth. in different producing area and investigate the effect of pyrolysis temperature and pyrolysis time on the fingerprint Methods Pyrolysis gas chromatography (PGC) and fuzzy cluster analysis were used Results Both similarity and charecteristics were found in the fingerprint of P. cablin in different producing area. The methodological evalulation showed that this method had a good reproducibility, RSD≤2.75% Conclusion This method is simple, rapid and accurate. It is suitable for the quality control of the Chinese materia medica with the important role of pyrolysis temperature and pyrolysis time