Research progress on pharmacological activities of triterpenes from Ganoderma lucidum / 中国药理学通报

Ganoderma lucidum is a valuable traditional Chinese medicine with dual use of medicine and food in China. Its chemical components mainly include triterpenoids, polysaccharides, organic acids, alkaloids, amino acids and so forth. The triterpenoids mainly include ganoderma acid and ganoderma alcohol. This paper has summarized the pharmacological activities of Ganoderma lucidum triterpenes in anti-tumor, anti-inflammatory, liver and kidney protection, immune regulation, blood lipid and blood glucose lowering, and antimicrobial activities in recent years, in order to provide reference basis for the core efficacy e-valuation of high-quality Ganoderma lucidum. It also provides scientific evidence for the application of Ganoderma lucidum in health food and clinical medicine.

Study progress on triterpenoids in Ganoderma lucidum / 中草药

The paper introduced the progress in study on triterpenoids in Ganoderma lucidum in recent years. The kinds of ganoderma triterpene, the pharmacological action, the biosynthesis pathway of ganoderma triterpene, and the influence factors of ganoderma triterpene accumulation were reviewed to provide the reference for the future development and utilization of ganoderma triterpene.

Effect of Ganoderma Triterpene on the Activation of Human T Lymphocyte / 中药新药与临床药理

Objective To investigate the effect of Ganoderma Triterpene(GT)on the expression of CD69 and HLA-DR on human T lymphocyte.Methods The activation of human T lymphocytes was detected and analyzed by flow cytometry after co-culturing with different concentrations of GT for 6 hours or for 72 hours.Results GT stimulated the expression of CD69 on T lymphocytes,the effect being significant at GT concentration of 10 ? g/mL(P