Gastric metastases of a malignant melanoma

Malignant melanoma accounts for around 5% of all malignant skin tumors. It is considered one of the most aggressive neoplasms due to its high metastasizing capacity. The most common sites of metastasis are peri-tumor lymph nodes, lung, brain and liver. The digestive tract is not a common site of metastasis. When involved, the small intestine is the organ most commonly affected. The stomach is a rare site of metastasis, found in only 7% percent of the cases. We report a case of a 72-year-old patient with a history of malignant melanoma who presented with acute epigastric pain. Enterotomography, upper endoscopy and additional biopsies confirmed the diagnosis of gastric metastases. (AU)

Cáncer renal y metástasis gástrica: reporte de un caso y revisión de la literatura / Renal cell carcinoma and gastric metastases: a case report and review of the literature

Objetivo: La metástasis gástrica del carcinoma de células renales es excepcional. Nosotros realizamos a una revisión de la literatura y presentamos un caso clínico. Métodos/Resultados: Varón de 62 años de edad, que se presenta con un tumor renal y metástasis gástrica detectados en una tomografía computada. Se realiza una nefrectomía radical más gastrectomía parcial. El paciente desarrolla metástasis progresivas y fallece siete meses más tarde. La revisión de la literatura revela que las metástasis gástricas producto de un carcinoma de células renales son excepcionales. Los casos reportados son principalmente detectados durante el seguimiento posterior a una nefrectomía, y generalmente asociados a una diseminación tumoral a otros órganos. El sangrado gastrointestinal como forma de presentación inicial del cáncer es muy infrecuente. El tratamiento consiste usualmente en manejo endoscópico del sangrado dado lo avanzado de la enfermedad. Conclusiones: Las metástasis gástricas en los pacientes con carcinoma de células renales son un evento tardío en el curso de la enfermedad, y el pronóstico es generalmente pobre.

Objective: Gastric metastases from renal cell carcinoma are exceptional. We reviewed the literature on this subject and present a case report. Method and Results: A 62 year old male patient presented with a renal tumor and a gastric metastasis detected on computed tomography. A radical nephrectomy and partial gastrectomy was performed. The patient developed progressive metastatic disease and died seven months later. Review of the literature shows that gastric metastases from renal cell carcinoma are exceptional. Cases reported are mainly detected during follow up after nephrectomy, generally associated with tumor spread to other organs. A gastrointestinal bleeding as a presenting sign of the cancer is very uncommon. Treatment usually consists in local endoscopic therapy to control the bleeding, due to advanced disease. Conclusions: Gastric metastases in patients with renal carcinoma are a late event in the course of the disease, and the outcome is generally poor.

Acute Upper Gastrointestinal Bleeding Due to Metastatic Lung Cancer: An Unusual Case

There have been several published reports on metastatic lesions in the stomach, but the number of cases have been limited due to the low frequency of the condition. Metastatic lesions in the stomach are usually asymptomatic. A 55-year-old man with known metastatic lung adenocancer exhibited epigastric pain, hematemesis, and melena. A bleeding, ulcerated gastric metastasis was found and treated with endoscopic therapy and omeprazole.