RESUMO
Objective: To study the chemical constituents of ethyl acetate extract from the whole herb of Pholidota articulata. Methods: Silica gel and Sephadex LH-20 gel column chromatographic techniques were used to separate and purify the chemical constituents. Their structures were elucidated based on NMR spectroscopic and reported data. Results: A total of 17 compounds were isolated from 78% ethyl acetate extracts of P. articulata and identified as flavidin (1), flaccidin (2), imbricatin (3), coelonin (4), lusianthridin (5), hircinol (6), gigantol (7), batatasin III (8), 5,3'-dihydroxy-3-methoxybibenzyl (9), cirrhopetalidin (10), β-sitosterol (11), stigmasterol (12), glut-5-en-3-ol (13), laurostearic acid (14), 4, 4'-dihydroxydiphenylmethane (15), 3-methoxy-benzaldehyde (16), and trans-cinnamic acid (17). Conclusion: Compounds 3-17 are isolated from this plant for the first time. In addition, compounds 9, 10, 13, and 16 are found in the genus Pholidota for the first time.