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Resumo O objetivo do estudo foi analisar a produção de livros e capítulos de livro dos bolsistas de produtividade do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) da área da Educação Física (PQ-EF), procurando entender a sua trajetória e verificar tendências das publicações e eventuais alterações nas suas características no período de 1991 a 2016. Foram analisados os currículos dos 91 bolsistas PQ-EF em curso no ano de 2017, no que diz respeito aos livros e capítulos de livro publicados, número de coautores e posição autoral dos bolsistas, por períodos definidos e por categoria de bolsistas. Os resultados mostraram um crescente aumento da produção de livros e capítulos de livro per capita e também um aumento na quantidade de autores por livro e capítulo de livro, sugerindo estratégias de publicação visando ao aumento de produtividade visualizadas na produção de artigos.
Abstract The study analyzes production of books and book chapters by Physical Education (PQ-EF) researchers who held productivity grants from Brazil's National Council for Scientific and Technological Development (CNPq), seeking to understand their trajectory and check trends regarding publications and possible changes in their characteristics in 1991-2016. The curricula of the 91 PQ-EF researchers holding productivity grants in 2017 were analyzed, with regard to books and book chapters, number of co-authors, and position among authors, for defined periods and by grant holder category. The results showed increase in the production of books and book chapters per capita and also in the number of authors per book and book chapter, suggesting publication strategies aimed at increasing productivity seen in production of articles.
Resumen El objetivo del estudio fue analizar la producción de libros y capítulos de libro de los becarios de productividad del Consejo Nacional de Desarrollo Científico y Tecnológico (CNPq) del área de Educación Física (PQ-EF), buscando comprender su trayectoria y verificar las tendencias de las publicaciones y posibles cambios en sus características en el período de 1991 a 2016. Se analizaron los currículos de los 91 becarios PQ-EF en curso en 2017, en lo que se refiere a los libros y capítulos de libro publicados, número de coautores y posición autoral de los becarios, por periodos definidos y por categoría de becarios. Los resultados mostraron un incremento creciente en la producción de libros y capítulos de libro per cápita y también un incremento en la cantidad de autores por libro y capítulo de libro, sugiriendo estrategias de publicación orientadas al aumento de productividad observada en la producción de artículos.
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Educação Física e Treinamento , Publicações , Livros , Educação de Pós-Graduação , Indicadores de Produção Científica , Bolsas de EstudoRESUMO
Este estudo buscou analisar a produção científica dos bolsistas de produtividade do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) da área da Educação Física (PQ-EF), procurando entender a sua trajetória e verificar tendências quanto a publicações de artigos e às eventuais alterações nas suas características no período de 1991 a 2016. Foram analisados os currículos dos 91 bolsistas PQ-EF em curso no ano de 2017, no que diz respeito aos artigos publicados em periódicos, número de coautores e posição na autoria dos artigos, como também a relação entre esses fatores por níveis de bolsa e tempo de término do doutorado. Os resultados revelaram um aumento expressivo da produção científica per capita e também um aumento de publicações multiautorais com número cada vez maior de coautores, sugerindo estratégias de publicação visando ao aumento de produtividade.
This study analyzes the scientific production by Physical Education (PQ-EF) PhD student researchers holding productivity grants from Brazil's National Council of Technological and Scientific Development (CNPq), in order to understand their trajectory and look into publication trends and possible changes in their characteristics in 1991-2016. The curricula of the 91 PQ-EF researchers holding grants in 2017 were analyzed in terms of articles published in journals, number of co-authors, and authors' positions in the articles, as well as how these factors relate according to productivity grant levels and time taken for completing their PhD studies. The results revealed a significant increase in per capita scientific production and also an increase in multi-author publications as well as the number of co-authors, suggesting publication strategies aimed at higher productivity.
Este estudio se propuso analizar la producción científica de los becarios de productividad del Consejo Nacional para el Desarrollo Científico y Tecnológico (CNPq) en el área de Educación Física (PQ-EF), tratando de comprender su trayectoria y verificar las tendencias con respecto a la publicación de artículos y los posibles cambios en sus características en el período de 1991 a 2016. Se analizaron los currículos de los 91 becarios PQ-EF en curso en 2017, en lo que se refiere a los artículos publicados en revistas, el número de coautores y la ubicación en la autoría de los artículos, así como la relación entre estos factores según los niveles de beca y el tiempo de finalización del doctorado. Los resultados revelaron un aumento significativo en la producción científica per cápita y también un aumento en las publicaciones de varios autores, con un número creciente de coautores, lo que sugiere estrategias de publicación destinadas a aumentar la productividad.
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Humanos , Educação Física e Treinamento , Educação de Pós-Graduação , Indicadores de Produção Científica , Publicações Periódicas como Assunto , Bolsas de EstudoRESUMO
Resumo O artigo analisa como as santas casas de misericórdia do estado de São Paulo foram subvencionadas pelos governos municipais, provincial e estadual na passagem do século XIX para o XX. Para tanto, são discutidas as dotações orçamentárias realizadas de 1838 a 1915, com o fim de avaliar o repasse e a ampliação de verbas nesse ínterim. É possível notar que foi criada uma rede de assistência fortemente apoiada pelo Estado, mas efetivada pela assistência filantrópica. Essa rede de atendimento hospitalar permanece com o mesmo formato até pelo menos o primeiro terço do século XX, contexto em que se incluíam as misericórdias criadas pelo interior do estado paulista.
Abstract This article investigates how the santas casas de misericórdia charitable associations in the state of São Paulo were subsidized by the municipal, provincial, and state governments at the turn of the twentieth century. Budget appropriations from 1838 to 1915 were examined to evaluate these charitable grants as well as the growth in funding during this period. While a care network created with strong state backing, it was put into action by philanthropic assistance. This network of hospital care retained the same format until at least the first third of the twentieth century, and included misericórdia establishments created within the interior of the state of São Paulo.
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Humanos , História do Século XVIII , História do Século XIX , História do Século XX , Instituições de Caridade/história , Política de Saúde/história , Hospitais/história , Brasil , Orçamentos/história , Instituições de Caridade/economia , Instituições de Caridade/legislação & jurisprudência , Economia Hospitalar/história , Financiamento Governamental/história , Governo/históriaRESUMO
OBJECTIVE: To introduce and compare research support for rare disease and orphan drug innovation in China and United States, and provide reference for relevant policies in China. METHODS: Data of main source of funding for rare disease research in two countries ie. National Institutes of Health, Food and Drug Administration in the United States and National Natural Science Foundation of China were analyzed and compared. RESULTS: US NIH gives substantial support for rare disease research every year with funded capital growing. FDA Orphan Products Grants program provides incentives for sponsors to develop products for rare diseases. In China, however, there is no specific support project for rare disease research, and there is a huge gap in funding efforts for rare disease research between China and the United States. CONCLUSION: China should establish rare disease research center to promote rare disease research and set up specific funding for rare diseases research, increase efforts to support research and innovation for rare diseases and orphan drugs, in order to protect the health interests of patients with rare diseases.
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STUDY DESIGN: Literature review. OBJECTIVES: The aim of this study was to present updated information on the research support programs offered by the National Research Foundation of Korea. SUMMARY OF LITERATURE REVIEW: The research support programs offered by the National Research Foundation of Korea are an important cornerstone for obtaining other grants from the government and commercial companies. However, no information has yet been provided in the literature about these programs. MATERIALS AND METHODS: Review of the relevant literature. RESULTS: The research support programs offered by the National Research Foundation of Korea are complex. However, it is possible to find appropriate grants. It is necessary to focus on the individual basic research program. CONCLUSIONS: Novel proposals have a greater chance of receiving funding, especially if the appropriate background and preliminary data are provided.
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Administração Financeira , Organização do Financiamento , Coreia (Geográfico)RESUMO
O objetivo desta pesquisa foi traçar o perfil dos pesquisadores bolsistas de Produtividade em Psicologia do Conselho Nacional de Desenvolvimento Científico e Tecnológico no triênio 2009-2011. O método utilizado foi de caráter transversal, descritivo, correlacional e de associação. Por meio de um levantamento de dados presentes nos currículos Lattes dos pesquisadores listados no site do Conselho Nacional de Desenvolvimento Científico e Tecnológico, buscou-se identificar relação entre a categoria de bolsa, a quantidade e a qualidade de suas produções. Os achados revelam diversidade, não permitindo traçar um perfil único de bolsistas. Predominam os bolsistas de categoria 2, distribuídos, em sua maioria, nas áreas de interesse da Psicologia do Desenvolvimento e Social. Verificou-se que, apesar de a qualidade das publicações acompanhar a categoria da bolsa, ainda predomina a quantidade em relação à qualidade das publicações, fenômeno conhecido como "produtivismo".
The aim of this study was to draw the profile of the psychology researchers funded with scientific productivity grants from the Conselho Nacional de Desenvolvimento Científico e Tecnológico from 2009-2011. We used a cross-sectional, descriptive and correlational method. Through a data survey using the Curriculum Lattes platform of all the researchers listed on the website of Conselho Nacional de Desenvolvimento Científico e Tecnológico, the purpose was to identify the relation between type of grant, quantity and quality of their production. The findings reveal diversity, which did not enable us to establish a unique profile of the researchers. Most researchers have a type-2 research grant and their interest is mainly distributed in Developmental and Social Psychology. Although the quality of publications is related to the type of grant, there is still a predominance of quantity over quality of publications, a phenomenon called "productivism".
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Humanos , Masculino , Feminino , Eficiência Organizacional , Psicologia , PesquisadoresRESUMO
Objective: Analysis on the financial influences of for Medicaid expenditure expansion. Methods: Using Economics analysis to study the relation between the method of Federal Medicaid grants and scope of States Medicaid. Results and Conclusion:The design of transfer payment motivated the states government to pursue maximizing Federal grants , which led to the medical expenditure expansion. The Policy aims on establishing unify Medicaid policy in the nation and all grants raised from the Federal government.
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BACKGROUND:The basic idea of artificial disc replacement is the intension to minimize the impact on adjacent segments based on the premise of stabilizing index segment, then prevent and reduce the incidence of adjacent segment degeneration. OBJECTIVE:To explore the indications and contraindications of artificial disc replacement, peri-operative economics considerations, long-term complications, as wel as the effect of artificial lumbar disc replacement combined with fusion surgery. METHODS:The PubMed database, CNKI database and SinoMed database over the past decade were searched for the related articles. The retrospective and prospective clinical trials of artificial lumbar disc replacement were included. Repetitive studies and stale perspectives were excluded. A total of 34 articles were summarized and analyzed in the end. RESULTS AND CONCLUSION:Since the first artificial lumbar disc prosthesis designed to be commercial y distributed in 1982, there have been a plenty of clinical trials on lumbar disc replacement. However, there is no answer to many problems that encountered in clinical trials. The effect of the number of replaced segment on the clinical outcomes, the effect of facet joint degeneration on the clinical outcomes, selection of the patients with the history of lumbar disc surgery, age of the patients and the rest time before disc replacement should be taken into consideration in the researches on indications and contraindications of artificial disc replacement. The intraoperative blood loss, operation time and hospital stay after replacement can be used to evaluate whether lumbar disc replacement is better than the traditional lumbar fusion surgery or not. The complications after lumbar disc replacement include heterotopic ossification, implants mechanical failure, and facet joint and adjacent segment degeneration. The combination of lumbar disc replacement and fusion surgery for the treatment of multi-segmental lumbar disc diseases can achieve complement and thus obtaining the efficacy that better than the application of one surgery alone.
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BACKGROUND:Insulin-like growth factor 1 is the key factor during cartilage development, which is involved in the growth and reconstruction of condylar cartilage. OBJECTIVE:To study the effect of insulin-like growth factor 1 on cel apoptosis and the apopotosis-associated factors of Bcl-2, Bax mRNA and protein expressions of rat condylar chondrocytes. METHODS:The 1-day-old and 28-day-old rat condylar chondrocytes were cultured and identified in vitro. The condylar chondrocytes with different ages were divided into experimental group and control group. After being starved for 24 hours, chondrocytes in the experimental group were incubated with 100μg/L recombined rat insulin-like growth factor 1 for 48 hours, while the chondrocytes in the control group were incubated normal y. RESULTS AND CONCLUSION:Compared with the control group, after being incubated with recombined insulin-like growth factor 1, the number of condylar chondrocytes was increased with high speed proliferation (Pproliferation and reduce cel apoptosis of newborn and adolescent rat condylar chondrocytes, which may be mediated by Bcl-2 and Bax.
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BACKGROUND:As a bone scaffold material,β-tricalcium phosphate has good biocompatibility, osteoinductive, and biomechanical properties. OBJECTIVE:To study the effect of al ogeneic osteoblasts compounded withβ-tricalcium phosphate in repairing rabbit radial defects. METHODS:A total of 45 rabbit radial defect models were made and divided into three groups in random. Experimental group was repaired with the compound of al ogeneic osteoblasts andβ-tricalcium phosphate; control group withβ-tricalcium phosphate;and blank control group with nothing. The new bone formation of each group was observed and assessed by X-ray and histopathological analysis at weeks 4, 8, 16 after implantation for evaluation of the bone repairing effect. RESULTS AND CONCLUSION:With the repair time, the experimental group appeared to complete bone defect repair gradual y. By the end of 16 weeks, the X-ray showed that the bone cal us between the scaffold and the host was completely ossified, and bone defects were completely repaired in the experimental group. Histopathological observation showed continuous cortical bone formed in the defect area, and canal recanalization realized in the experimental group. Additional y, the repair effect in the experimental group was better than that in the control and blank control group at different time points (P<0.01). It is suggested that the al ogenic osteoblasts/β-tricalcium phosphate compound has the better effects on guiding bone regeneration and preventing from nonunion.
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BACKGROUND:Orthotopic lung transplantation model in a rat is the key to investigate the chronic rejection after lung transplantation. However, the precise surgical technique and difficult operation limit the application of the model. OBJECTIVE:To improve the process of anesthesia and lung transplantation, and to establish a rapid, safe and reversible rat lung transplantation model. METHODS:A total of 42 rats were used to establish the model, including 21 donor models and 21 receptor models. The donor lung was excised by median sternotomy with dissection of the left lung and implantation of cuffs (intravenous catheters cut into 1.5 mm sections). The left lung was implanted in the recipient by lateral thoracotomy using the cuffs for anastomoses. The duration of surgery and success rate of transplantation were recorded and calculated. RESULTS AND CONCLUSION:The survival rate of rats after lung transplantation was 100%. The time of left donor lung extraction was (35.3±5.1) minutes in average. The time of placing cuff in donor lung was (12.5±4.6) minutes in average. The surgical procedure time of recipient was (50.2±3.3) minutes. The time of arteriovenous and bronchus casing anastomosis was (27.7±6.2) minutes. After pulmonary artery and vein blood flow was disparked, the whole lung turned red rapidly, blood perfusion was sufficient, venous returned unimpeded;after mechanical ventilation resumed, al graft lungs expanded wel . This improved anesthesia and lung transplantation technique in rats can provide a valid, reliable and reproducible animal model for studying immune responses and rejection in lung transplantation.
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BACKGROUND: During conventional treatment for bone tuberculosis, there is a low effective concentration of anti-tuberculosis drugs, and the therapeutic effect is poor. OBJECTIVE:To develop a new biomaterial as a slow-release artificial carrier that can be directly implanted into the surrounding tissue of bone tuberculosis, maintain a certain anti-tuberculosis drug concentration for a long time, thereby playing an effective therapeutic action. METHODS:Rifampicin/polylactic acid/glycolic acid microspheres and isoniazid/polylactic acid/glycolic acid microspheres were prepared using the emulsion-solvent evaporation method. Usingα-cyanoacrylate, a biological adhesive, two kinds of microspheres were processed into a long-term slow-release bicomponent drug carrier. Then, in vitro release characteristics of the dual-drug sustained-release carrier were observed. After that, the dual-drug sustained-release carrier was implanted into rabbit intertrochanteric femur bone defects for observing drug release concentrations, histocompatibility and bone defect healing at different time points after drug delivery carrier implantation. RESULTS AND CONCLUSION:For rifampicin/polylactic acid/glycolic acid microspheres, the mean particle size was (240±13)μm, and the drug loading load rate was (26±1.5)%. For isoniazid/polylactic acid/glycolic acid microspheres, the mean particle size was (250±10)μm, and drug loading rate was (28±1.8)%. The in vitro cumulative release rate could reach 80%for rifampicin and 90%for isoniazid at day 90. The in vivo released concentration of rifampicin and isoniazid within 90 days was (0.5±0.4) and (0.6±0.3)μg/g, respectively. There were a smal amount of infiltrated neutrophils between the fascia and muscle fibers after the drug delivery carrier was implanted, and the amount of neutrophils in the muscle were reduced significantly at day 59. X-ray plain film showed that bone defects decreased obviously in size. These findings indicate that this dual-drug sustained-release carrier can maintain a certain anti-tuberculosis drug concentration in the surrounding tissues of bone tuberculosis, which is expected to provide a new type of dual-drug delivery carrier in the surgical treatment of bone tuberculosis.
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BACKGROUND:Through a ful investigation of biodegradable scaffolds, we propose a new self-expanding degradable poly-L-lactide coated endotracheal stent based on the design, production, experimental and clinical applications of nickel titanium memory alloy stent. OBJECTIVE:To design a kind of biodegradable endotracheal stent with poly-L-lactide and hydroxyapatite, and to test its mechanical properties, biocompatibility and biodegradation capacity. METHODS:With the technology of computer aided design, the stents were prepared with poly-L-lactide (Mr RESULTS AND CONCLUSION:The average radial supporting force of the tracheal stent was 7.8 kPa, the percentage of stent surface coverage was less than 20%, the stent expansion rate was≥4%, and the stent longitudinal shortening rate was≤9%, which reached the mechanical requirements for degradable endotracheal stents. After 4-16 weeks, there was no significant inflammatory response. The decline in molecular weight changes and weight loss ratio was higher for in vivo degradation than in vitro degradation at different time (P<0.05). These findings indicate that poly-L-lactide/hydroxyapatite composite stents have good mechanical properties, biocompatibility and biodegradability. 150 000) and hydroxyapatite materials, 20 mm to 26 mm in diameter. The mechanical properties were tested using a universal testing machine. These poly-L-lactide/hydroxyapatite stents were implanted into dog models of tracheal stenosis at an appropriate size. The histopathological changes of the tracheas were observed, and biodegradation property was studied via molecular weight changes and weight loss ratio after 4, 8, 12, 16 weeks.
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BACKGROUND: Vascular endothelial growth factor play an important role in promoting healing of osteoporotic fractures, but whether it can affect the bone mineral density is not clear. OBJECTIVE: To observe the correlation between serum vascular endothelial growth factor, bone mineral density and the number of osteoblasts in the ovariectomized rats. METHODS: Forty female Sprague-Dawley rats were randomly divided into ovariectomized group and control group. After 3 months, the bone mineral density of the whole body, femur and lumbar spine was measured. Rat enzyme-linked immunosorbent assay kit was used to measure the level of serum vascular endothelial growth factor. Then, the rats in two groups received femoral metaphyseal fixation, decalcified, dehydrated, embeding in paraffin, slicing and hematoxylin-eosin staining. Each slice was free to take five fields of view (10×40) in order to count the osteoblasts of femur distal metaphysis under optical microscope. RESULTS AND CONCLUSION: After ovariectomized for 3 months, the rats body mass was increased significantly (P 0.05), and the difference of the osteoblast number between ovariectomized group and control group was not significant (P > 0.05). This indicated that there was no correlation between bone mineral density and the number of osteoblasts and vascular endothelial growth factor level in the ovariectomized group and the control group. These findings suggest that the bone mineral density is reduced and the body mass is increased in the ovariectomized rats, and the reduced bone mineral density of ovariectomized rats may be irrelevant with the change of serum vascular endothelial growth factor.
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10.3969/j.issn.2095-4344.2013.23.011
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10.3969/j.issn.2095-4344.2013.26.001
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10.3969/j.issn.2095-4344.2013.26.004
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10.3969/j.issn.2095-4344.2013.26.015
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10.3969/j.issn.2095-4344.2013.25.002
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10.3969/j.issn.2095-4344.2013.25.014