PAIN MANAGEMENT OF COVID–19 INFECTED PATIENTS AFTER THE VACCINATION: A PROSPECTIVE STUDY

Background: COVID-19 is a severe infectious disease (SID) claimed that >180,000 lives are infected millions in the elderly population globally. Emerging evidences we observed that virus to cause hemorrhagic and immunologic responses impact in all the organs, including lungs, kidneys, eye , the brain, and extremities as well as. We had Material and Methods: performed with prospectively of >1,500 articles and included 525 references from our online databases, including with the Scopus, PubMed, Medline, Google Scholar, and the wave of Sciences. COVID-19 patients are also going through the acute respiratory distress syndrome (ARDS), cytokine storm (CS), acute hypercoagulable state (AHCS), and the autonomic dysfunction (ADF) managed by the multidisciplinary team approach. This is including with Physical medicine rehabilitation, medicine, nursing, nutrition, and rehabilitation and the other important radiological ?ndings. A total no of 30 vaccines under the developmental process (DP), Results: and now newly developed with their guidelines for the better treatment strategies and newly developed protocols are being well implemented. The majority of 80-95% of elderly population those are suffering from neurological diseases (ND-90-95%), Alzheimer's disease (AD-85%, Parkinsonism Diseases (PD-95%) and dementia (D-80%) related illnesses noticed that they are at higher risk during COVID-19 pandemic. The future management for COVID-19 should include B-cell and T-cell immunotherapy in combination with all the emerging prophylaxis is also more helpful. The pain CONCLUSION: management in the neurological disorders (ND) including with all the mental health with several illness aspects of the COVID-19 is the most important side effects of during the pandemic. Hence the national level and International level plan for prevention, diagnosis and treatment for SARS-CoV-2 also affects patients', families', society's neurological disorders (ND), Alzheimer's disease (AD), Parkinsonism Diseases (PD), Dementia Diseases (DD), and the other mental health patients at larger in population. Now growing evidence of re-infection in some neurological disorders (ND) patients is to provide a comprehensive knowledge of SARS-CoV-2-induced with neurological diseases (NDs) and their mechanism of infection (MOI), diagnostics, therapeutics, and their new treatment strategies, focusing with less attended aspects including with the nutritional support, psychological, and physical medicine and rehabilitation and its management are essential for elders, youth, and children.

Implementation of Nationwide Evidence- and Consensus-Based Guidelines to Harmonize Neonatal Care in The Netherlands

Background: A Dutch committee for National Guidelines in Neonatology developed nineteen evidence- and consensusbased guidelines to be used in all Dutch neonatal intensive care units (NICUs). The primary goal was to make clinical practices more uniform and consistent. Objective: This study investigated to what extent the guidelines were implemented and which factors played a role in implementation. Study design: A mixed method study design was used to investigate both the level and the process of implementation. A nationwide, multicenter, cross-sectional survey was performed using a validated instrument for measuring the level of implementation (Normalization MeAsure Development questionnaire, NoMAD). The number of implemented guidelines per NICU and the frequency and content of the amendments that NICUs made to the original consensus guidelines were analyzed. Through semistructured interviews, perceived barriers and facilitators for implementation were explored. Participants: Fellows and neonatologists working at all ten Dutch level 3-4 NICUs were eligible. Results: On an average, NICUs implemented 12.6 (of 19) guidelines (range 6-17). The Normalization Process Scale was 54 (of 65). Main influencing factors impeding implementation were guideline-related (e.g., unpractical, lengthy guidelines) and personal (e.g., an active representative responsible for local implementation). Conclusion: The implementation of our guidelines appears to be successful. Ways for improvement can be distinguished in personal, guideline-related and external factors. Empowerment of local representatives was considered most essential.

Developing process of guide on methodological standards in pharmacoepidemiology (T/CPHARMA 002-2019) / 中华流行病学杂志

Pharmacoepidemiology refers to the use of epidemiological research methods in studying the application and use of drugs in large populations to evaluate the safety and efficacy of medical products. Therefore, standardized pharmacoepidemiology research is the basis of the above work. Based on systematic reviews of national and international pharmacoepidemiological methodological standards and guidelines, and in combination with Chinese medical and health practice and experts’ opinions, the Professional Committee of Pharmacoepidemiology of Chinese Pharmaceutical Association developed the group standard, guide on methodological standards in pharmacoepidemiology (T/CPHARMA 002-2019), to better guide the work of pharmacoepidemiology. The guideline was designed to provide advice and reference for pharmacoepidemiology research by government, regulatory agencies, research institutions, and pharmaceutical manufacturers in China.

What It Takes To Set Up Travel Health Services: A Review From Countries With Established Service

@#As air travelling now becomes cheaper and available to almost all people of any walk of life, travelling across international borders is fast becoming a lifestyle of many. Having travel health service as part of health care services is important to address the issues of travel related illnesses among travellers. However, lacks of published guidelines pertaining to travel health service rendering many countries to overlook its importance. The aim of this paper is to review published literatures and authoritative websites on the components needed to develop guideline to establish travel health services. A systematic literature search was done using pre-specified keywords for literatures published between years 2000 – 2016. Literatures written in English and fully accessible were all included. No exclusion criteria was set before the search. Online authoritative websites pertaining to travel health were also referred. A total of six literatures ranging from expert opinion, review paper and original study, together with three authoritative websites related to travel health were reviewed. Among the important components needed to be considered for developing the guideline for establishing travel health services are to prioritise pre-travel health service, to set up specialised travel health clinic, to produce travel health/medicine specialist, to emphasize on continuous education and training of the practitioners and to apply multiagency and multidisciplinary approach with adequate fund for research in travel health. As a conclusion, policy makers should prioritise and select the most important components in developing guideline for travel health service.

Development and Implementation of Clinical Practice Guidelines: Current Status in Korea

Documentation of unexplained geographic variations in medical practices and use of inappropriate interventions has led to the proliferation of clinical practice guidelines. With increased enthusiasm for guidelines, evidence exists that clinical practice guidelines often influence clinical practices or health outcomes. Their successful implementation may improve the quality of care by decreasing in appropriate variation and expediting the application of effective advances to healthcare practices. In Korea, physicians and healthcare professionals have begun to take interests in clinical practice guidelines. Currently, over 50 practice guidelines have been developed through professional academic organizations or via other routes; however, the quality of the guidelines is unsatisfactory, implementation in clinical settings is incomplete, and there is insufficient infrastructure to develop clinical practice guidelines. Korea must develop policies and invest resources to enhance the development and implementation of clinical practice guidelines.