Halo Congenital Nevus Developed after a Laser Treatment / 대한피부과학회지

No abstract available.

Halo Congenital Nevus Followed by Periocular Vitiligo / 대한피부과학회지

Halo nevus is a pigmented nevus surrounded by acquired round depigmentation. Depigmentation appears mostly around several types of pigmented lesions, such as acquired nevus, congenital nevus, blue nevus and Spitz nevus. In contrast, it is rare that depigmentation develops around a congenital nevus. While the precise etiology of halo nevus and vitiligo remains uncertain, several theories suggest that both phenomena result from an immunologic reaction to melanocytes by CD8 + T cell. We report a case of halo congenital nevus in the arm, which is followed by periocular vitiligo. This is the third case in Korean dermatological literature.

Halo Congenital Nevus Associated with Extralesional Vitiligo / 대한피부과학회지

Halo nevus is a pigmented nevus surrounded by a round or oval depigmentation. Of patients with halo nevus, 18 to 26% patients have vitiligo, either involving the nevus or at a distant site. While the exact etiology of halo formation and vitiligo is unknown, several theories suggest that common immunologic mechanisms are involved in the destruction of melanocytes of both phenomena. Unlike common melanocytic nevus, congenital nevus associated with both halo formation and concurrent extralesional vitiligo is very uncommon and only one case has been reported in the Korean dermatological literature. A 19-year-old female presented with surrounding depigmentation around a congenital hairy nevus on the left forearm. Simultaneously, vitiligo appeared on the lowerabdomen and surrounding regions of both areola. The halo depigmented lesion around congenital nevus and the periareolar vitiliginous lesion shared some histological and immunohistochemical features. These findings further support common immunological mechanisms of pigment destruction in both phenomena.

A Case of Halo Congenital Nevus / 대한피부과학회지

The term halo congenital nevus is a condition in which halo formation is associated with congenital melanocytic nevus. The regression of congenital melanocytic nevi is usually accompanied by the halo phenomenon and this is considered to be a rare event, although this may be underestimated. We describe here a 9-year-old boy with verrucous congenital nevus surrounded by a depigmented halo on the right upper arm. Histologically, the nevus lesion revealed a dense lymphocytic infiltration in the upper dermis intermingled with some remnants of nevus cell nests. Most of the infiltrating cells were CD8+ T lymphocytes. At the edge of the lesion, corresponding to the area of the halo, neither melanocytes nor melanin were found in any significant amounts.

A Case of Halo Congenital Nevus / 대한피부과학회지

A halo nevus is a pigmented nevus surrounded by a depigmented zone. It usually occurs in childhood or adolescence. Depigmented zone may form around a variety of acquired melanocytic lesions of neuroectodermal origin, including nevocellular nevi, blue nevi, spindle and epithelioid nevi, primary and metastatic melanomas, and neurofibromas. The occurrence of a halo around congenital melanocytic nevi has rarely been reported. We report a case of halo congenital nevus in a 11-year-old girl.

A Case of Halo Congenital Nevus Undergoing Spontaneous Regression / 대한피부과학회지

Halo congenital nevus is a condition in which halo formation is associated with congenital nevocellular nevus. Both humoral and cell-mediated immunity have been implicated to be involved in halo formation. We described a 8-year-old boy with halo congenital nevus characterized by the unique histologic location of inflammatory cells. He has no personal and familial history of vitiligo, dysplastic nevus, melanoma or autoimmune disease. Histologically, the present case of halo congenital nevus undergoing spontaneous regression showed a marked inflammatory infiltrate with remnants of original nevus cell nests in the upper dermis, whereas no inflammatory infiltrate was present in the deep dermis. Most of inflammatory cells were T-cells.