Diagnóstico terapéutico para la atención de pacientes con caries dental / Therapeutic diagnosis for the care of patients with dental caries

La caries dental es tan antigua como la humanidad misma, es considerada por la Organización Mundial de la Salud como el primer problema de salud bucal, su incremento se ha asociado al desarrollo social y a las variaciones en los hábitos dietéticos de las poblaciones. En estudios realizados en los últimos años, se ha determinado una tendencia a la disminución de esta enfermedad. El problema fundamental en el diagnóstico y tratamiento de la caries dental es la decisión de cuándo y cómo obturar un diente afectado por caries. El objetivo primario es ampliar la visión sobre las posibilidades terapéuticas y profundizar en los conocimientos teóricos y prácticos sobre los tratamientos preventivos, curativos no invasivos e invasivos utilizados contra la caries dental. Se realizó una revisión bibliográfica de textos impresos y búsqueda en internet sobre caries dental, frecuencia y conducta adecuada por parte los estomatólogos generales. Se concluye que todo estomatólogo general, debe conocer la importancia de la promoción y la prevención permanente en los pacientes para evitar las caries dentales, así como las indicaciones, técnica de empleo y los requisitos para aplicar en la práctica diaria, los materiales restaurativos(AU)

Dental caries is as old as human race, it is considered by the World Health Organization as the first oral health problem, its increase has been associated with social development and variations in dietary habits of populations. In studies carried out in recent years, a tendency to decrease this disease has been determined. The fundamental problem in the diagnosis and treatment of dental caries is the decision of when and how to seal a tooth affected by caries. The primary objective is to broaden the vision of the therapeutic possibilities and to deepen the theoretical and practical knowledge about preventive, non-invasive and invasive curative treatments used against dental caries. A literature review of printed texts and internet search on dental caries, frequency and appropriate behavior of general stomatologists was carried out. It is concluded that every general stomatologist should know the importance of the promotion and permanent prevention in patients to avoid tooth decay, as well as the indications, technique of use and requirements to apply restorative materials in daily practice.

Production of vegetable oil blends and structured lipids and their effect on wound healing / Produção de misturas de óleos vegetais e lípidos estruturados e o seu efeito na cicatrização de feridas

Two oil blends (sunflower/canola oils 85/15 (BL1) and canola/linseed oils 70/30 (BL2)), were prepared and enzymatically interesterified to be applied to surgically-induced wounds in rats. Following surgery, the animals were submitted to the Treatment with Physiological Saline (TPS) (control group), Blends (TBL), and Structured Lipids (TSL). The control group (TPS) received physiological saline solution for 15 days. In TBL, BL1 was administered during the inflammation phase (days 0-3) and BL2 in the tissue formation and remodeling phase (days 4-15). In TSL, Structured Lipid 1 (SL1) and Structured Lipid 2 (SL2) were used instead of BL1 and BL2, respectively. The aim of this study was to compare wound closure evolution among rats treated with the blends or structured lipids versus control rats treated with physiological saline. The wound healing process was evaluated by measuring the wound areas along the treatments and the concentrations of cytokines. An increase in the areas of wounds treated with the blends and structured lipids in the inflammatory phase was observed, followed by a steeper closure curve compared to wounds treated with physiological saline. The changes observed during the inflammatory phase suggest a potential therapeutic application in cutaneous wound healing which should be further investigated...

Duas misturas de óleos vegetais (girassol/canola 85/15 (BL1) e canola/linhaça, 70/30 (BL2) foram preparadas e interesterificadas por via enzimática para serem aplicadas em feridas induzidas cirurgicamente em ratos. Após a cirurgia, os animais foram submetidos ao tratamento com soro fisiológico (TPS) (grupo controle), tratamento com as misturas (TBL) e tratamento com os lipídios estruturados (TSL). O grupo controle (TPS) recebeu soro fisiológico por 15 dias. Em TBL, BL1 foi administrada durante a fase de inflamação (dias 0-3) e BL2 na fase de formação de tecido e remodelação (dias 4-15). Em TSL, os lipídios estruturados SL1 e SL2 foram usados em vez de BL1 e BL2, respectivamente. O objetivo deste estudo foi avaliar a evolução do fechamento das feridas dos grupos de ratos tratados com as misturas ou lipídios estruturados em comparação com os ratos do grupo controle, tratados com soro fisiológico. O processo de cicatrização das feridas foi avaliado através da medição das áreas das feridas ao longo dos tratamentos e pela determinação das concentrações de citocinas. Observou-se aumento das áreas das feridas tratadas com as misturas e os lipídios estruturados na fase inflamatória, seguida por um fechamento acentuado de feridas comparado com o tratamento com solução salina. As mudanças observadas durante a fase inflamatória sugerem uma potencial aplicação terapêutica na cicatrização de feridas cutâneas, fazendo-se necessárias investigações posteriores...