Effects of aprotinin versus tranexamic acid on blood coagulation and platelet function in patients undergoing valve replacement / 中华麻醉学杂志

Objective It has been shown that aprotinin and tranexamic acid are equally effective in protecting platelet and reducing postoperative bleeding. The aim of this study was to compare the effects of aprotinin and tranexamic acid on blood coagulation. Methods Thirty patients undergoing elective valve replacement were randomly divided into two groups : (1) aprotinin group (AP, P