Hidradenoma Papilliferum of the Anus: A Report of 2 Cases and Review of the Literature

Hidradenoma papilliferum is a rare benign cystic tumor that originates from apocrine glands or anogenital mammary glands. Here, we describe 2 cases of hidradenoma papilliferum of the anus. Two female patients aged 39 and 35 presented with perianal masses with hemorrhoids. The patients underwent hemorrhoidectomy and excision of the lesion. Histopathology confirmed the masses as hidradenoma papilliferum. The postoperative course was uneventful for both patients, and there were no recurrences after 18 and 12 months of follow-up, respectively. Proctologists should consider hidradenoma papilliferum in their differential diagnosis of benign anal tumors. Surgical excision is necessary for diagnosis and treatment of hidradenoma papilliferum.

Ectopic hidradenoma papilliferum of eyelid: A rare entity with diagnostic challenge

Hidradenoma papilliferum is a rare cutaneous adnexal tumour of middle aged females arising mainly in the apocrine sweat glands of perianal and genital region. Ectopic forms of this entity have been described with majority of them occurring on the head and neck region. We report a case of 16 years young male who presented with two small, well circumscribed, greyish-brown, firm, nodules on his left upper and lower eyelid. A clinical impression of basal cell carcinoma was assumed but on histopathological examination it was diagnosed as hidradenoma papilliferum of eyelid. Immunohistochemistry was performed to support the diagnosis due to its unusual clinical presentation. To the best of our knowledge, only six cases in the upper eyelid and one case in the lower eyelid have been reported in the English literature. This is the first case report of hidradenoma papilliferum involving both upper and lower left eyelid in an adolescent boy.

Perianal hidradenoma papilliferum / Hidradenoma papilífero perianal

ABSTRACT Hidradenoma papilliferum is a benign cystic tumor originated in apocrine sweat glands of the anogenital region. It is common in vulvar topography and rare in the perianal region. A well-documented case of a patient with slow-growing perianal nodulation without pain or other symptoms is reported. The histological study shows a hidradenoma papilliferum. The article reviews the topic and discusses the importance of the differential diagnosis of proctological conditions. A biopsy is mandatory in anal lesions of unusual presentation.

RESUMO O hidradenoma papilífero é um tumor cístico benigno originado nas glândulas sudoríparas apócrinas da região anogenital, sendo comum em topografia vulvar e raro na região perianal. Relata-se um caso bem documentado de paciente com nodulação perianal de crescimento lento, sem dor ou outros sintomas, cujo estudo histológico revelou se tratar de hidradenoma papilífero. O artigo revisa o tema e discute a importância do diagnóstico diferencial das afecções proctológicas, sendo a biópsia obrigatória em lesões anais de apresentação não-usual.

Localización inusual del hidradenoma papilífero / Unusual location of the papilliform hydradenoma

El hidradenoma papilífero es una tumoración benigna, rara, generalmente localizada en la región vulvar o perineal siendo la región perianal una localización poco frecuente. Su asociación con enfermedades de transmisión sexual y el carcinoma ductal es controvertida; es importante realizar el estudio histopatológico de cualquier tumoración en esta zona. Se reporta el caso de una paciente de 49 años de edad, con un nódulo en la región perianal de 2 años de evolución; el estudio histopatológico confirmó el diagnóstico de hidradenoma papilífero. (AU)

The papilliferous hidradenoma is a benign, rare tumor, usually located in the vulvar or perineal region and the perianal region is a rare site. Its association with sexually transmitted diseases and ductal carcinoma is controversial. It is important to perform the histopathological study of any tumor in this area. The case of a 49-year-old patient with a nodule in the perianal region of 2 years of evolution is reported. The histopathological study confirmed the diagnosis of papilliferous hidradenoma.

Hidradenoma Papilliferum of the Back / 대한피부과학회지

No abstract available.

A Case of Ectopic Hidradenoma Papilliferum / 대한피부과학회지

No abstract available.

Hidradenoma papilífero: reporte de tres casos y revisión de la literatura / Hidradenoma papilliferum: report of three cases and review of the literature

El hidradenoma papilífero es un tumor infrecuente que ocurre casi de manera exclusiva en la región anogenital de las mujeres, sin embargo se han descrito casos de hidradenomas papilíferos ectópicos. Las lesiones generalmente son asintomóticas de crecimiento lento, eritematosas, firmes, y se presentan como un nódulo bien delimitado. Reportamos tres casos de hidradedoma papilífero en región vulvar, diagnosticados entre 2009 y 2010 en el Hospital Universitario de Caracas. En los tres casos se presente una lesión única, nodular, en labio mayor, con diámetro < 10 mm, renitente, nacarada, no pruriginosa. Hasta la actualidad se ha reportado solo un caso en laliteratura venezolana

Hidradenoma papilliferum is a rare tumor that occurs almost exclusively in the anogenital region of women, however has been reports ectopic hidradenoma papilliferum. The lesions are usually asymptomatic, slow-growing, erythematous, firm, and are presented as awell-defined nodule. We report three cases of vulvar hidradenoma papillifirum, diagnosed between 2009 and 2010 at the Hospital Universitario de Caracas. In all three cases was presented as a single, nodular lesion in labia major with a diameter < 10mm, firm, pearly, not itchy. Until now it has been reported only one case in Venezuelan literature

Hidradenoma Papilliferum Occurring on the Nasal Skin

Hidradenoma papilliferum is a rare benign neoplasm that usually occurs in the female anogenital area. We present a 43-year-old female with a non-anogenital (ectopic) hidradenoma papilliferum on her nose. The patient had had a skin-colored subcutaneous nodule on her nose for 7 years. The histopathological findings showed variously shaped cystic spaces in the tumor. And the lumina were surrounded by a single or double layer of cell which showed decapitation secretion. In the English dermatological literature, only one case of ectopic hidradenoma papilliferum arising in nasal skin has been reported. Hence we suggest hidradenoma papilliferum occurring on the nasal skin is a peculiar and interesting event.

A Case of Hidradenoma Papilliferum on the Cheek of an Adult Male / 대한피부과학회지

Hidradenoma papilliferum is a benign, cystic, papillary tumor that occurs almost exclusively in women on the skin of the anogenital region and this is usually a slow-growing cystic dermal mass that can be either asymptomatic or it can ulcerate and bleed, and it represents an adenoma with apocrine differentiation. Nonanogenital (ectopic) hidradenoma papilliferum is rare. We present here a case of hidradenoma papilliferum in a 52-year old male with an erythematous to brownish nodule on the left cheek and the lesion had the typical histopathological findings of hidradenoma papilliferum.

A Case of Hidradenoma Papilliferum with Transepidermal Elimination / 대한피부과학회지

Transepidermal elimination is a process by which the skin eradicates undesirable or irritative dermal substances through intact epidermis or follicular epithelium by passive or active means. Although transepidermal elimination is being described in an increasing number and range of pathological processes, transepidermal elimination of hidradenoma papilliferum remains unrecorded to date in the Korean literature. We report a new case of hidradenoma papilliferum with transepidermal elimination. A 32-year-old woman presented with a bean-sized, protruding flesh red-colored nodule on the left labia major. The histologic finding of the lesion indicated a tubular and cystic structure microscopically expelled through the transepidermal canal.

A Case of Hidradenoma Papilliferum / 대한피부과학회지

Hidradenoma papilliferum is a rare benign neoplasm that occurs almost exclusively on the skin of the female anogenital region. It is usually a slow-growing cystic dermal mass that can be either asymptomatic or ulcerate and bleed, and represents an adenoma with apocrine differentiation. We present a case of hidradenoma papilliferum in a 46-year old woman with a erythematous to brownish papule on the left labium majora and the typical histopathologic findings.

A Case of Hidradenoma Papilliferum of the Nipple / 대한피부과학회지

We report a case of hidradenoma papilliferum of the left nipple in a 23-year-old female patient. Hidradenoma papilliferum occurs only in women, usually on the labia majora or in the perineal or perineal region and represents an adenoma with apocrine dif ferentiation. Histologic examination of the lesion revealed findings consistent with hidradenoma papilliferurn. She had been performed surgical excision