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Background: An evaluation of intrathecal hyperbaric ropivacaine without adjuvant and with adjuvant magnesium for lower abdominal surgeries.Methods: This was a prospective, randomized, double-blind study conducted among the patients aged 18 to 60 years planned for lower abdomen surgeries under spinal anaesthesia and ASA grade I or II. Patients were randomly allocated to two groups (30 in each): ropivacaine Group (R group): spinal anesthesia with 3ml of 0.6% hyperbaric ropivacaine (18mg )+ 0.5ml NS. hyperbaric ropivacaine + Magnesium Group (R+M group ): spinal anesthesia with 3ml of 0.6% hyperbaric ropivacaine (18mg) + 0.5ml magnesium sulphate (50 mg). All the patients scheduled for operation were given oral tablets ranitidine 150 mg and Alprazolam 0.25mg in the night before surgery.Results: There was no significant difference in the basic characteristics between the groups. The mean HR, MAP and SpO2 in both the groups decreased over the periods as compared to baseline. However, the trend of HR over the periods remains similar in both R and R+M groups. The bromage levels were significantly (p=0.0001) higher among the patients of Group R compared with R+M. The 2 segment sensory regression (min), Sensory regression S2 (hr), motor recovery (hrs) and long term mobilization after spinal anesthesia were significantly (p=0.0001) lower among the patients of Group R compared with R+M. The complications were lower in Group R+M than R.Conclusions: Magnesium may be more suitable drug in surgeries in which muscle relaxation has greater value in lower abdominal surgeries.
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Objective To assess the anesthetic effect of different concentrations of hyperbaric ropivacaine used in lumbar anesthesia for elderly transurethral prostatic resection. Methods We randomly divided 58 elderly patients who un-derwent transurethral prostatic resection with ASA (American Surgical Association) physical status level Ⅰ-Ⅱ into 2 groups as group A and B, using numeric random table method. Each group includes 29 cases. After being punctured between L3-L4, patients were injected with 0.5%(group A) and 0.75%(group B) hyperbaric ropivacaine (diluted with 10%glucose) to the subarachnoid space in a speed of 0.1-0.3 mL/s and the overall dose was 12.5 mg in each case. Then the extents of sen-sory and motor block were compared between two groups, and their anesthesia effect and adverse reactions were also record-ed. Results Compared with group A, onset time of sensory block in group B was significantly shorter (P＜0.05), while onset time for motor block was of no significant difference;By contrast to group A, acting time of sensory block in group B pro-longed significantly (P＜0.05) while acting time of motor block was of no statistically significant difference(P>0.05);By con-trast to group A, the anesthesia effect of group B was more effective while the adverse reactions of the two groups was of no significant difference (P>0.05). Conclusion 0.75%hyperbaric ropivacaine in lumbar anesthesia for elderly patients un-dergoing transurethral prostatic resection could provide a better anesthesia and analgesia effect than 0.5%hyperbaric ropiva-caine without more significant adverse reactions.