Calcinosis escrotal idiopática: Reporte de un caso / Idiopathic scrotal calcinosis. A case report

Resumen El calcio participa en muchos procesos fisiológicos. La calcinosis cutis es una enfermedad de depósito de calcio en la dermis. La calcicosis escrotal idiopática (CEI) es una forma común de calcinosis cutis idiopática. Se presenta el caso de un paciente masculino de 28 años de edad, con clínica de masas múltiples en escroto, de color blanco, tamaños variados, no dolorosas. Los niveles de calcio y fósforo se mostraron dentro de los rangos normales, característico de calcinosis de tipo idiopática, mientras que la vitamina D y la PTH se mostraron fuera de los límites normales. Se realiza una cirugía menor de las lesiones nodulares circunscritas, de diversos tamaños y de bordes regulares. El examen histológico post-biopsia confirmó el diagnóstico de calcinosis cutis. Se prescribió una dieta baja en calcio como método preventivo a largo plazo. A pesar de lo infrecuente de esta condición debe tenerse en cuenta al realizar un diagnóstico diferencial. Su etiología es aún desconocida y puede presentarse de manera asintomática. Lo importante es brindar al paciente una mejor calidad de vida, evitar incomodidades y baja autoestima debido al aspecto estético.

Abstract Calcium participates in many physiological processes. Calcinosis cutis is a disease caused by calcium deposition in the dermis. Idiopathic scrotal calcinosis (ICS) is a common form of idiopathic calcinosis cutis. A 28-year-old male patient was evaluated, with symptoms of multiple white masses in the scrotum, of various sizes, not painful. Calcium and phosphorus levels were within normal ranges, characteristic of idiopathic calcinosis, while vitamin D and PTH were outside the normal limits. Minor surgery was performed on circumscribed nodular lesions of various sizes with regular borders. Post-biopsy histological examination confirmed the diagnosis of calcinosis cutis. A low-calcium diet was prescribed as a long-term preventive method. Despite the infrequency of this condition, it should be taken into account when making a differential diagnosis. Its etiology is still unknown and it can present asymptomatically. The important thing is to provide the patient with a better quality of life, avoid discomfort and low self-esteem due to the aesthetic aspect.

Idiopathic Calcinosis Cutis in Scrotum – A Rare Subtype

Idiopathic calcinosis cutis is a rare disorder and occurs in the absence of known tissue injury or systemic metabolic defect. It is a skin calcification process with abnormal deposits of calcium phosphate in the skin in various parts of the body. It is a rare and benign syndrome which does not cause any late complication and whose prognosis is therefore favourable. Hereby, I am reporting a case of 40 years old male who presented with multiple asymptomatic calcified nodules in the scrotum with normal lab findings. Excision of the nodule on histopathological examination revealed foci of calcification separated by fibrous septa in the dermis.

Two Cases of Milia-like Idiopathic Calcinosis Cutis Occurred in Infants / 대한피부과학회지

No abstract available.

Calcinosis cutis idiopática universal / Calcinosis cutis idiopathic universal

La calcinosis cutis es un trastorno raro causado por el depósito anormal de sales de calcio en la piel y tejido subcutáneo. Clínicamente se caracteriza por pápulas, placas o nódulos calcificados. Según su etiopatogenia se distinguen cinco tipos clínicos: distrófica, metastásica, iatrogénica, idiopática y calcifilaxis.Comunicamos el caso clínico de un paciente en edad pediátrica con una calcinosis cutis idiopática universal, sin afectación extra-cutánea. Esta publicación reviste importancia debido a lo infrecuente de esta enfermedad y a que su diagnóstico nos permite detectar padecimientos asociados, que son determinantes para el pronóstico y tratamiento.

Cutaneous calcinosis is a rare disorder caused by the deposit of abnormal calcium salts in the skin and subcutaneous tissue. Itpresents with calcified papules, plaques or nodules. Five clinical types are distinguished: dystrophic, metastatic, iatrogenic, idiopathic and calcifilaxis. This paper reports a pediatric patient with aidiopathic calcinosis cutisuniversalis, without extracutaneous manifestations. This publication is important because of the rarity of this disease. The diagnosis allows us to investigate the possible associated diseases that determine patient prognosis and treatment.

A Case of Milia-like Idiopathic Calcinosis Cutis in an Elderly Person / 대한피부과학회지

No abstract available.

Extensive idiopathic calcinosis / Journal of the ASEAN Federation of Endocrine Societies

@#A 60-year-old Indian male with a 2 year history of diabetes mellitus on insulin therapy and a past history of right sided hemiparesis due to cerebrovascular accident (CVA) presented with fracture of the neck of the left femur after a fall. X-ray showed extensive vascular calcifications, scrotal calcification and severe osteoporosis.

Idiopathic calcinosis of the scrotum and literature review / 中国综合临床

Objective To investigate the clinical features,diagnosis and treatment experience of idiopathic calcinosis of the scrotum(ICS).Methods We report 5 cases with a 4-month to 20-year history of ICS.The related literatures were reviewed.Results The multiple scrotum masses in these patients were increased slowly in size and number.The levels of blood calcium and phosphorus were normal.Histopathologically,nodules were composed of basophilic calcified material and located in the dermis.There was no epithelial lining around the calcified nodules.Conclusion ICS is a rare localized benign disease.The diagnosis of the tumor relies largely on the histopathology.Surgical excision is the best choice for treatment.

Idiopathic Calcinosis Cutis: Clinical and Histopathologic Review in a Series of 30 Patients (2000-2009) / 대한피부과학회지

BACKGROUND: Idiopathic calcinosis cutis (CC) is currently sub-classified as tumoral CC, sub-epidermal calcified nodules, idiopathic CC of the scrotum, and milia-like CC. This sub-classification system is obscure and can be confusing at times. OBJECTIVE: This study was designed to characterize the clinical and histologic features of idiopathic CC, to evaluate the adequacy of the current sub-classification system, and to propose a new sub-classification system. METHODS: Thirty patients with idiopathic CC were sub-classified according to the Lever classification and the Walsh and Fairley classification and were also categorized based on the type of the primary lesion. RESULTS: Idiopathic CC lesions were most common on the buttock (n=7), followed by the scrotum (n=5), arms and legs (n=5), hands and feet (n=4), inguinal area (n=3), ears (n=2), neck (n=2), trunk (n=1), and face (n=1). With the Lever classification, twenty-three of 30 cases were categorized as "unclassified". With the Walsh and Fairley classification, twenty-three cases were categorized as "unclassified", whereas with our new classification system, we managed to classify all cases as either nodular or papular calcification according to the type of the primary lesion. CONCLUSION: In this study, we identified a common location and the primary morphological features of idiopathic CC. Our findings suggest that our new sub-classification system based on the type of the primary lesion would be useful.

Calcinose universal idiopática: apresentação em recém-nascido / Idiopathic calcinosis universalis: infant presentation

A calcinose universal idiopática é uma doença rara, de diagnóstico difícil e que se manifesta em recém-nascidos e crianças. Relatamos o caso de um paciente recém-nascido, do sexo masculino, apresentando calcificação limitada ao tecido subcutâneo do membro superior direito.

The idiopathic calcinosis universalis is a rare disorder of unknown cause which affects infants and children. This article reports on a case of a recent born male patient showing limited calcification inthe subcutaneous tissue of the right upper arm.

A Case of Milia-like Idiopathic Calcinosis Cutis That Improved with Tretinoin Cream / 대한피부과학회지

Milia-like idiopathic calcinosis cutis is a rare entity. It is characterized by micronodular, whitish papules resembling milia. Histopathological examination shows small nodular foci of calcium within the superficial dermis, which are surrounded by thick collagen and inflammatory cells. Although the pathogenesis and treatment remain unclear, spontaneous resolution of the lesions may occur. We report a case of milia-like idiopathic calcinosis cutis in a 7-year-old girl who improved after treatment with tretinoin cream.

A Case of Milia-like Idiopathic Calcinosis Cutis in Healthy Boy / 대한피부과학회지

Milia-like idiopathic calcinosis cutis (MICC) is a peculiar subtype of idiopathic calcinosis cutis, characterized by clinically resembling milia, and the majority of the cases are associated with Down syndrome. We report a rare case of MICC which was not associated with Down syndrome. A healthy 10-year-old boy presented with whitish papules surrounded by erythema on the back. Some of the papules were umbilicated or crusted, therefore, they gave a clinical impression as molluscum contagiosum. Histopathologic findings of the papule showed calcium deposits as amorphous, basophilic mass on the upper dermis and focal transepidermal elimination of calcium, which were compatible with MICC.

A Case of Milia-like Idiopathic Calcinosis Cutis and Periorbital Syringomas in Down Syndrome / 대한피부과학회지

Down syndrome is associated with a large number of abnormal skin features including syringoma. Milia-like idiopathic calcinosis cutis is one of the rare dermatoses associated with Down syndrome. It has been reported in children with Down syndrome and clinically suggested as milia. The histological features show small nodular foci of calcium within the papillary dermis and transepidermal elimination of calcium deposits occasionally. We describe a 14-year-old female affected by Down syndrome, who had whitish papules on both the dorsal hands and feet and periorbital syringomas. Histopathological findings of the papule on the dorsal hand showed calcium deposits as amorphous, basophilic masses in the upper dermis and focal discharge of calcium by means of transepidermal elimination.

A Case of Therapeutic Experience in Idiopathic Calcinosis of the Scrotum / 대한피부과학회지

A 23-year-old male patient had 65 nodules of 0.2~0.7 cm in diameter nn scrotum. Elliptical excision was done to remove the nodules situated on the middle part of the scrotum. For small multiple nodules on the lower part of the scroelectrocogulation and curretage was performed. Excellent results were obtained by two modalities of treatment.