Normalize the imaging diagnosis of cerebral small vessel disease / 中华神经科杂志

The diagnosis of cerebral small vessel disease (CSVD) is highly dependent on neuroimaging, and its imaging changes include lacune, lacunar infarction, white matter hyperintensity (WMH), perivascular space (PVS), cerebral microbleed, etc. In previous studies, the definitions of these imaging changes were quite different, resulting in misdiagnosis of lacuna, WMH and PVS. This comment will summarize the clinical, imaging, and pathological characteristics of CSVD, sort out the process and effectiveness of the gradually normalized diagnostic standards, and propose errors that should be avoided, aiming to improve the accuracy and consistency of clinical diagnosis and research.

Revolution CT hepatic perfusion imaging assessment of peripheral infiltration zone of hepatic alveolar echinococcosis / 中国血吸虫病防治杂志

Objective To analyze the blood supply and metabolism in the marginal area of foci of hepatic alveolar echinococcosis by quantitative perfusion parameters. Methods Thirty patients with hepatic alveolar echinococcosis were scanned with the Revolution CT and the images were analyzed. The perfusion parameters, such as the bloodflow (BF), time to peak (TTP), blood volume (BV), mean transit time (MTT) and hepatic arterial fraction (HAF) were compared among different groups. Results The BF, TTP, BV and MTT values of the peripheral infiltration zone and the values of the surrounding normal liver tissues were significantly different (F = 24.579, 8.343, 20.535 and 21.843, all P<0.05), but the HAF values of the peripheral infiltration zone and the values of the surrounding normal liver tissues were not significantly different in the hepatic alveolar echinococcosis patients (F = 2.621, P> 0.05) . Conclusion The whole hepatic perfusion Revolution CT can accurately and quantitatively analyze the alveolar echinococcosis foci, especially the peripheral infiltration zone, which has important guiding significance for the formulation of surgical plan.

Revolution CT hepatic perfusion imaging assessment of peripheral infiltration zone of hepatic alveolar echinococcosis / 中国血吸虫病防治杂志

Objective To analyze the blood supply and metabolism in the marginal area of foci of hepatic alveolar echinococcosis by quantitative perfusion parameters. Methods Thirty patients with hepatic alveolar echinococcosis were scanned with the Revolution CT and the images were analyzed. The perfusion parameters, such as the bloodflow (BF), time to peak (TTP), blood volume (BV), mean transit time (MTT) and hepatic arterial fraction (HAF) were compared among different groups. Results The BF, TTP, BV and MTT values of the peripheral infiltration zone and the values of the surrounding normal liver tissues were significantly different (F = 24.579, 8.343, 20.535 and 21.843, all P<0.05), but the HAF values of the peripheral infiltration zone and the values of the surrounding normal liver tissues were not significantly different in the hepatic alveolar echinococcosis patients (F = 2.621, P> 0.05) . Conclusion The whole hepatic perfusion Revolution CT can accurately and quantitatively analyze the alveolar echinococcosis foci, especially the peripheral infiltration zone, which has important guiding significance for the formulation of surgical plan.

Quantitative radiological evaluation of interaction of lumbar vertebral bone marrow fat, bone mineral density and age / 中华放射学杂志

Objective To explore the change patterns in the lumbar vertebral bone marrow fat content with age, analyze the interactions between lumbar vertebral bone marrow fat content, bone mineral density (BMD), and age, and compare the difference of lumbar vertebral bone marrow fat content between males and females in the same age groups. Methods According to the statistical sample size requirements that the minimum sample size of each group was 18, thus, we prospectively recruited healthy volunteers who met the inclusion criteria. Among them, there were 139 males and females, with age range of 21-70 years old. According to age, the patients were divided into group 1 (21-30-yr), group 2 (31-40-yr), group 3 (41-50-yr), group 4 (51-60-yr), and group 5 (61-70-yr). Quantitative computed tomography (QCT) was used to measure the lumbar vertebral BMD, and MR mDIXON-Quant technique was used to measure the marrow fat content of L3 lumbar vertebra. We compared the difference of lumbar vertebral bone marrow fat content and BMD between different age groups in males and females using one-way ANOVA, and compared the difference of lumbar vertebral bone marrow fat content and BMD between males and females in the same age groups using t-test. Correlation analysis was conducted between bone marrow fat content, BMD and age. Results Lumbar vertebral bone marrow fat content was generally increasing with the age. There were significant differences in the fat content of bone marrow at different age groups (male, F=13.598, P=0.000;female, F=73.419, P=0.000). Before the age of 50 years, lumbar vertebral bone marrow fat content in females was lower than one in males, and there was a significant difference between group 2 [females,(29.7± 7.1)%-(36.1 ± 6.6)%, males,(34.1 ± 8.4)%-(39.9 ± 5.9)%;21-30-yr, t=1.984, P=0.053;31-40-yr, t=5.699, P=0.000;41-50-yr, t=2.017, P=0.050]. Females older than 50 years had a higher marrow fat content than males, and there was a significant difference between group 5 [females,(48.3±8.8)%-(52.5±8.2)%, males, (45.5 ± 8.1)%-(46.2 ± 7.4)%;51-60-yr, t=-0.914, P=0.365;61-70-yr, t=-3.400, P=0.001]. For males, bone marrow fat content was positively correlated with age (r=0.527, P<0.05), and negatively correlated with BMD (r=-0.730, adjusted for age r=-0.584, P<0.05). For females, bone marrow fat content was positively correlated with age (r=0.761, P<0.05), and negatively correlated with BMD (r=-0.809, adjusted for age r=-0.473, P<0.05). Conclusions Lumbar vertebral bone marrow fat content was generally increasing with the age. Bone marrow fat content was positively correlated with age and negatively correlated with BMD for males and females.

Quantitative radiological evaluation of interaction of lumbar vertebral bone marrow fat, bone mineral density and age / 中华放射学杂志

Objective To explore the change patterns in the lumbar vertebral bone marrow fat content with age, analyze the interactions between lumbar vertebral bone marrow fat content, bone mineral density (BMD), and age, and compare the difference of lumbar vertebral bone marrow fat content between males and females in the same age groups. Methods According to the statistical sample size requirements that the minimum sample size of each group was 18, thus, we prospectively recruited healthy volunteers who met the inclusion criteria. Among them, there were 139 males and females, with age range of 21-70 years old. According to age, the patients were divided into group 1 (21-30-yr), group 2 (31-40-yr), group 3 (41-50-yr), group 4 (51-60-yr), and group 5 (61-70-yr). Quantitative computed tomography (QCT) was used to measure the lumbar vertebral BMD, and MR mDIXON-Quant technique was used to measure the marrow fat content of L3 lumbar vertebra. We compared the difference of lumbar vertebral bone marrow fat content and BMD between different age groups in males and females using one-way ANOVA, and compared the difference of lumbar vertebral bone marrow fat content and BMD between males and females in the same age groups using t-test. Correlation analysis was conducted between bone marrow fat content, BMD and age. Results Lumbar vertebral bone marrow fat content was generally increasing with the age. There were significant differences in the fat content of bone marrow at different age groups (male, F=13.598, P=0.000;female, F=73.419, P=0.000). Before the age of 50 years, lumbar vertebral bone marrow fat content in females was lower than one in males, and there was a significant difference between group 2 [females,(29.7± 7.1)%-(36.1 ± 6.6)%, males,(34.1 ± 8.4)%-(39.9 ± 5.9)%;21-30-yr, t=1.984, P=0.053;31-40-yr, t=5.699, P=0.000;41-50-yr, t=2.017, P=0.050]. Females older than 50 years had a higher marrow fat content than males, and there was a significant difference between group 5 [females,(48.3±8.8)%-(52.5±8.2)%, males, (45.5 ± 8.1)%-(46.2 ± 7.4)%;51-60-yr, t=-0.914, P=0.365;61-70-yr, t=-3.400, P=0.001]. For males, bone marrow fat content was positively correlated with age (r=0.527, P<0.05), and negatively correlated with BMD (r=-0.730, adjusted for age r=-0.584, P<0.05). For females, bone marrow fat content was positively correlated with age (r=0.761, P<0.05), and negatively correlated with BMD (r=-0.809, adjusted for age r=-0.473, P<0.05). Conclusions Lumbar vertebral bone marrow fat content was generally increasing with the age. Bone marrow fat content was positively correlated with age and negatively correlated with BMD for males and females.

Neuroimaging assessment of collateral circulation in acute cerebral infarction / 医学研究生学报

Acute cerebral infarction is a common disease of the central nervous system, the key of the current treatment is to restore blood flow and save ischemic penumbra .The studies have shown that good collateral circulation can reduce the infarction area, improve prognosis.Thus, an accurate and complete evaluation of collateral circulation in the early stage of disease has an important sig -nificance.The development of modern imaging techniques provides important means for the assessment of collateral circulation estab -lishment in acute stroke .In this paper, techniques and methods of the imaging examination of collateral circulation establishment in a -cute cerebral infarction and methods are reviewed, aiming to provide the basis for choosing reasonable imaging modality .